Magnesium »
PDB 4fig-4fs2 »
4fr8 »
Magnesium in PDB 4fr8: Crystal Structure of Human Aldehyde Dehydrogenase-2 in Complex with Nitroglycerin
Enzymatic activity of Crystal Structure of Human Aldehyde Dehydrogenase-2 in Complex with Nitroglycerin
All present enzymatic activity of Crystal Structure of Human Aldehyde Dehydrogenase-2 in Complex with Nitroglycerin:
1.2.1.3;
1.2.1.3;
Protein crystallography data
The structure of Crystal Structure of Human Aldehyde Dehydrogenase-2 in Complex with Nitroglycerin, PDB code: 4fr8
was solved by
B.S.Lang,
K.Gruber,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 37.07 / 2.20 |
| Space group | P 1 21 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 101.663, 175.916, 102.296, 90.00, 95.01, 90.00 |
| R / Rfree (%) | 13.2 / 16.7 |
Other elements in 4fr8:
The structure of Crystal Structure of Human Aldehyde Dehydrogenase-2 in Complex with Nitroglycerin also contains other interesting chemical elements:
| Sodium | (Na) | 8 atoms |
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Crystal Structure of Human Aldehyde Dehydrogenase-2 in Complex with Nitroglycerin
(pdb code 4fr8). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 8 binding sites of Magnesium where determined in the Crystal Structure of Human Aldehyde Dehydrogenase-2 in Complex with Nitroglycerin, PDB code: 4fr8:
Jump to Magnesium binding site number: 1; 2; 3; 4; 5; 6; 7; 8;
In total 8 binding sites of Magnesium where determined in the Crystal Structure of Human Aldehyde Dehydrogenase-2 in Complex with Nitroglycerin, PDB code: 4fr8:
Jump to Magnesium binding site number: 1; 2; 3; 4; 5; 6; 7; 8;
Magnesium binding site 1 out of 8 in 4fr8
Go back to
Magnesium Binding Sites List in 4fr8
Magnesium binding site 1 out
of 8 in the Crystal Structure of Human Aldehyde Dehydrogenase-2 in Complex with Nitroglycerin
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Magnesium with other atoms in the Mg binding
site number 1 of Crystal Structure of Human Aldehyde Dehydrogenase-2 in Complex with Nitroglycerin within 5.0Å range:
|
Magnesium binding site 2 out of 8 in 4fr8
Go back to
Magnesium Binding Sites List in 4fr8
Magnesium binding site 2 out
of 8 in the Crystal Structure of Human Aldehyde Dehydrogenase-2 in Complex with Nitroglycerin
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Magnesium with other atoms in the Mg binding
site number 2 of Crystal Structure of Human Aldehyde Dehydrogenase-2 in Complex with Nitroglycerin within 5.0Å range:
|
Magnesium binding site 3 out of 8 in 4fr8
Go back to
Magnesium Binding Sites List in 4fr8
Magnesium binding site 3 out
of 8 in the Crystal Structure of Human Aldehyde Dehydrogenase-2 in Complex with Nitroglycerin
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Magnesium with other atoms in the Mg binding
site number 3 of Crystal Structure of Human Aldehyde Dehydrogenase-2 in Complex with Nitroglycerin within 5.0Å range:
|
Magnesium binding site 4 out of 8 in 4fr8
Go back to
Magnesium Binding Sites List in 4fr8
Magnesium binding site 4 out
of 8 in the Crystal Structure of Human Aldehyde Dehydrogenase-2 in Complex with Nitroglycerin
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Magnesium with other atoms in the Mg binding
site number 4 of Crystal Structure of Human Aldehyde Dehydrogenase-2 in Complex with Nitroglycerin within 5.0Å range:
|
Magnesium binding site 5 out of 8 in 4fr8
Go back to
Magnesium Binding Sites List in 4fr8
Magnesium binding site 5 out
of 8 in the Crystal Structure of Human Aldehyde Dehydrogenase-2 in Complex with Nitroglycerin
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Magnesium with other atoms in the Mg binding
site number 5 of Crystal Structure of Human Aldehyde Dehydrogenase-2 in Complex with Nitroglycerin within 5.0Å range:
|
Magnesium binding site 6 out of 8 in 4fr8
Go back to
Magnesium Binding Sites List in 4fr8
Magnesium binding site 6 out
of 8 in the Crystal Structure of Human Aldehyde Dehydrogenase-2 in Complex with Nitroglycerin
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Magnesium with other atoms in the Mg binding
site number 6 of Crystal Structure of Human Aldehyde Dehydrogenase-2 in Complex with Nitroglycerin within 5.0Å range:
|
Magnesium binding site 7 out of 8 in 4fr8
Go back to
Magnesium Binding Sites List in 4fr8
Magnesium binding site 7 out
of 8 in the Crystal Structure of Human Aldehyde Dehydrogenase-2 in Complex with Nitroglycerin
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Magnesium with other atoms in the Mg binding
site number 7 of Crystal Structure of Human Aldehyde Dehydrogenase-2 in Complex with Nitroglycerin within 5.0Å range:
|
Magnesium binding site 8 out of 8 in 4fr8
Go back to
Magnesium Binding Sites List in 4fr8
Magnesium binding site 8 out
of 8 in the Crystal Structure of Human Aldehyde Dehydrogenase-2 in Complex with Nitroglycerin
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Magnesium with other atoms in the Mg binding
site number 8 of Crystal Structure of Human Aldehyde Dehydrogenase-2 in Complex with Nitroglycerin within 5.0Å range:
|
Reference:
B.S.Lang,
A.C.Gorren,
G.Oberdorfer,
M.V.Wenzl,
C.M.Furdui,
L.B.Poole,
B.Mayer,
K.Gruber.
Vascular Bioactivation of Nitroglycerin By Aldehyde Dehydrogenase-2: Reaction Intermediates Revealed By Crystallography and Mass Spectrometry. J.Biol.Chem. V. 287 38124 2012.
ISSN: ISSN 0021-9258
PubMed: 22988236
DOI: 10.1074/JBC.M112.371716
Page generated: Fri Aug 16 15:15:10 2024
ISSN: ISSN 0021-9258
PubMed: 22988236
DOI: 10.1074/JBC.M112.371716
Last articles
Zn in 9JYWZn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
