Magnesium in PDB 4g5g: Ef-Tu (Escherichia Coli) Complexed with Nvp-LDU796

The structure of Ef-Tu (Escherichia Coli) Complexed with Nvp-LDU796, PDB code: 4g5g was solved by D.Palestrant, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 2.30
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	80.305, 123.577, 45.092, 90.00, 90.00, 90.00
R / Rfree (%)	n/a / n/a

The binding sites of Magnesium atom in the Ef-Tu (Escherichia Coli) Complexed with Nvp-LDU796 (pdb code 4g5g). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Ef-Tu (Escherichia Coli) Complexed with Nvp-LDU796, PDB code: 4g5g:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Ef-Tu (Escherichia Coli) Complexed with Nvp-LDU796


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Ef-Tu (Escherichia Coli) Complexed with Nvp-LDU796 within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg501 b:34.9 occ:1.00 O A:HOH615 2.2 22.6 1.0 OG1 A:THR25 2.2 32.8 1.0 O2B A:GDP502 2.3 30.8 1.0 O A:HOH601 2.3 22.0 1.0 O A:HOH602 2.4 25.4 1.0 O A:HOH616 2.4 34.1 1.0 CB A:THR25 3.4 32.3 1.0 PB A:GDP502 3.5 32.7 1.0 O1B A:GDP502 3.5 26.9 1.0 O A:CYS81 3.7 29.9 1.0 OD1 A:ASP50 4.0 42.1 1.0 O A:PRO82 4.1 36.2 1.0 CA A:PRO82 4.1 32.5 1.0 OD2 A:ASP80 4.1 38.5 1.0 N A:THR25 4.1 29.0 1.0 O2A A:GDP502 4.2 32.7 1.0 O A:HOH622 4.3 26.4 1.0 CA A:THR25 4.4 29.5 1.0 C A:CYS81 4.4 30.7 1.0 CG2 A:THR25 4.4 28.4 1.0 O3A A:GDP502 4.4 31.7 1.0 O3B A:GDP502 4.5 32.1 1.0 C A:PRO82 4.5 33.7 1.0 N A:PRO82 4.6 31.0 1.0 OD1 A:ASP80 4.7 37.1 1.0 CG A:ASP80 4.8 34.8 1.0 PA A:GDP502 4.8 34.1 1.0 O A:HOH605 4.8 37.2 1.0 NZ A:LYS24 5.0 29.8 1.0 CE A:LYS24 5.0 35.1 1.0 O A:HOH604 5.0 32.6 1.0

Magnesium binding site 2 out of 2 in the Ef-Tu (Escherichia Coli) Complexed with Nvp-LDU796


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Ef-Tu (Escherichia Coli) Complexed with Nvp-LDU796 within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg503 b:23.4 occ:0.50 O A:HOH654 2.3 38.9 1.0 O A:HOH653 2.4 38.4 1.0 O A:HOH681 2.4 50.8 1.0 OE2 A:GLU152 3.2 55.0 1.0 CD A:GLU152 4.0 53.0 1.0 O A:PRO111 4.1 38.1 1.0 O A:ASP109 4.2 41.7 1.0 OE1 A:GLU152 4.3 54.1 1.0 CD A:PRO111 4.8 37.9 1.0 N A:PRO111 4.9 38.1 1.0 CA A:GLY110 5.0 39.0 1.0 C A:GLY110 5.0 39.9 1.0

M.J.Lamarche, J.A.Leeds, J.Dzink-Fox, E.Gangl, P.Krastel, G.Neckermann, D.Palestrant, M.A.Patane, E.M.Rann, S.Tiamfook, D.Yu. Antibiotic Optimization and Chemical Structure Stabilization of Thiomuracin A. J.Med.Chem. V. 55 6934 2012.
ISSN: ISSN 0022-2623
PubMed: 22812377
DOI: 10.1021/JM300783C