Atomistry » Magnesium » PDB 4ha3-4hlq » 4he2
Atomistry »
  Magnesium »
    PDB 4ha3-4hlq »
      4he2 »

Magnesium in PDB 4he2: Crystal Structure of Human Muscle Fructose-1,6-Bisphosphatase Q32R Mutant Complex with Amp

Enzymatic activity of Crystal Structure of Human Muscle Fructose-1,6-Bisphosphatase Q32R Mutant Complex with Amp

All present enzymatic activity of Crystal Structure of Human Muscle Fructose-1,6-Bisphosphatase Q32R Mutant Complex with Amp:
3.1.3.11;

Protein crystallography data

The structure of Crystal Structure of Human Muscle Fructose-1,6-Bisphosphatase Q32R Mutant Complex with Amp, PDB code: 4he2 was solved by R.Shi, D.W.Zhu, S.X.Lin, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 50.00 / 1.60
Space group P 42 21 2
Cell size a, b, c (Å), α, β, γ (°) 73.366, 73.366, 146.622, 90.00, 90.00, 90.00
R / Rfree (%) 18.1 / 19.4

Other elements in 4he2:

The structure of Crystal Structure of Human Muscle Fructose-1,6-Bisphosphatase Q32R Mutant Complex with Amp also contains other interesting chemical elements:

Chlorine (Cl) 1 atom
Zinc (Zn) 1 atom

Magnesium Binding Sites:

The binding sites of Magnesium atom in the Crystal Structure of Human Muscle Fructose-1,6-Bisphosphatase Q32R Mutant Complex with Amp (pdb code 4he2). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 3 binding sites of Magnesium where determined in the Crystal Structure of Human Muscle Fructose-1,6-Bisphosphatase Q32R Mutant Complex with Amp, PDB code: 4he2:
Jump to Magnesium binding site number: 1; 2; 3;

Magnesium binding site 1 out of 3 in 4he2

Go back to Magnesium Binding Sites List in 4he2
Magnesium binding site 1 out of 3 in the Crystal Structure of Human Muscle Fructose-1,6-Bisphosphatase Q32R Mutant Complex with Amp


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of Human Muscle Fructose-1,6-Bisphosphatase Q32R Mutant Complex with Amp within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mg403

b:17.8
occ:0.75
 ZN A:ZN404 1.7 17.2 0.2
OD1 A:ASP121 1.9 28.1 1.0
O2 A:PO3402 2.1 19.1 0.8
OE2 A:GLU280 2.2 24.1 1.0
OD2 A:ASP118 2.3 25.5 1.0
O A:HOH740 2.5 32.3 1.0
P A:PO3402 2.8 25.3 0.8
CG A:ASP121 3.0 26.8 1.0
CD A:GLU280 3.3 21.0 1.0
CB A:ASP121 3.4 24.5 1.0
CG A:ASP118 3.4 22.9 1.0
CA A:ASP121 3.5 24.4 1.0
O3 A:PO3402 3.6 24.5 0.8
OE1 A:GLU97 3.7 23.7 0.5
MG A:MG405 3.7 22.0 1.0
O1 A:PO3402 3.8 19.8 0.8
CG A:GLU280 3.8 17.8 1.0
OD1 A:ASP118 3.9 23.1 1.0
OD2 A:ASP121 4.1 28.4 1.0
O A:HOH741 4.1 16.4 1.0
N A:GLY122 4.2 26.0 1.0
OE1 A:GLU280 4.3 21.2 1.0
O A:HOH625 4.3 27.4 1.0
C A:ASP121 4.4 25.3 1.0
OE2 A:GLU97 4.4 23.0 0.5
CE A:MET248 4.4 14.0 0.5
CD A:GLU97 4.6 24.5 0.5
CB A:ASP118 4.6 19.2 1.0
N A:ASP121 4.6 23.3 1.0
OE2 A:GLU97 4.6 24.7 0.5
CD1 A:ILE135 4.7 20.9 1.0
O A:LEU120 4.7 25.6 1.0
O A:HOH561 4.8 24.1 1.0
CD A:GLU97 4.9 24.1 0.5

Magnesium binding site 2 out of 3 in 4he2

Go back to Magnesium Binding Sites List in 4he2
Magnesium binding site 2 out of 3 in the Crystal Structure of Human Muscle Fructose-1,6-Bisphosphatase Q32R Mutant Complex with Amp


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Crystal Structure of Human Muscle Fructose-1,6-Bisphosphatase Q32R Mutant Complex with Amp within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mg405

b:22.0
occ:1.00
 O2 A:PO3402 1.9 19.1 0.8
O A:HOH524 2.0 19.2 1.0
OE2 A:GLU97 2.1 23.0 0.5
O A:HOH561 2.1 24.1 1.0
OE2 A:GLU97 2.1 24.7 0.5
OD1 A:ASP118 2.2 23.1 1.0
O A:LEU120 2.2 25.6 1.0
ZN A:ZN404 2.8 17.2 0.2
CD A:GLU97 3.0 24.5 0.5
P A:PO3402 3.0 25.3 0.8
CG A:ASP118 3.0 22.9 1.0
CD A:GLU97 3.1 24.1 0.5
C A:LEU120 3.2 23.2 1.0
OD2 A:ASP118 3.2 25.5 1.0
OE1 A:GLU97 3.3 23.7 0.5
OE1 A:GLU97 3.6 24.6 0.5
O3 A:PO3402 3.7 24.5 0.8
MG A:MG403 3.7 17.8 0.8
MG A:MG406 3.7 20.9 0.5
CA A:ASP121 3.8 24.4 1.0
N A:ASP121 3.9 23.3 1.0
O1 A:PO3402 3.9 19.8 0.8
OE2 A:GLU98 4.0 33.2 1.0
OD1 A:ASP74 4.0 42.7 1.0
O A:HOH600 4.2 27.7 1.0
N A:LEU120 4.2 21.6 1.0
CA A:LEU120 4.3 22.8 0.5
CA A:LEU120 4.3 23.0 0.5
CG A:GLU97 4.3 23.3 0.5
OG A:SER123 4.3 35.6 1.0
CG A:GLU97 4.4 22.8 0.5
CB A:ASP118 4.4 19.2 1.0
CB A:GLU97 4.6 23.0 0.5
CB A:GLU97 4.6 22.9 0.5
CB A:ASP121 4.8 24.5 1.0
CD A:PRO119 4.8 20.6 1.0
C A:ASP121 4.9 25.3 1.0
CA A:ASP118 4.9 19.3 1.0
OE2 A:GLU280 4.9 24.1 1.0
CB A:LEU120 4.9 23.8 0.5
O A:HOH628 4.9 20.0 1.0
C A:ASP118 4.9 19.5 1.0
N A:PRO119 4.9 19.8 1.0
N A:GLY122 5.0 26.0 1.0
CB A:LEU120 5.0 24.0 0.5
OD1 A:ASP121 5.0 28.1 1.0

Magnesium binding site 3 out of 3 in 4he2

Go back to Magnesium Binding Sites List in 4he2
Magnesium binding site 3 out of 3 in the Crystal Structure of Human Muscle Fructose-1,6-Bisphosphatase Q32R Mutant Complex with Amp


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of Crystal Structure of Human Muscle Fructose-1,6-Bisphosphatase Q32R Mutant Complex with Amp within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mg406

b:20.9
occ:0.50
 O A:HOH628 1.9 20.0 1.0
O3 A:PO3402 2.0 24.5 0.8
O A:HOH600 2.1 27.7 1.0
O A:HOH757 2.2 31.6 1.0
OE1 A:GLU97 2.3 24.6 0.5
O A:HOH561 2.4 24.1 1.0
P A:PO3402 2.9 25.3 0.8
OE2 A:GLU97 3.0 24.7 0.5
CD A:GLU97 3.3 24.1 0.5
O1 A:PO3402 3.6 19.8 0.8
OE2 A:GLU97 3.6 23.0 0.5
CD A:GLU97 3.6 24.5 0.5
O2 A:PO3402 3.6 19.1 0.8
MG A:MG405 3.7 22.0 1.0
O A:HOH649 3.7 36.7 1.0
OE1 A:GLU97 3.9 23.7 0.5
OG A:SER123 4.2 35.6 1.0
ZN A:ZN404 4.2 17.2 0.2
OE2 A:GLU98 4.2 33.2 1.0
O A:HOH576 4.3 25.6 1.0
O A:HOH524 4.5 19.2 1.0
O A:HOH648 4.6 39.4 1.0
CG A:GLU97 4.6 22.8 0.5
CG A:GLU97 4.6 23.3 0.5
CB A:SER123 4.7 34.1 1.0
OD1 A:ASP74 4.8 42.7 1.0

Reference:

R.Shi, Z.Y.Chen, D.W.Zhu, C.Li, Y.Shan, G.Xu, S.X.Lin. Crystal Structures of Human Muscle Fructose-1,6-Bisphosphatase: Novel Quaternary States, Enhanced Amp Affinity, and Allosteric Signal Transmission Pathway. Plos One V. 8 71242 2013.
ISSN: ESSN 1932-6203
PubMed: 24086250
DOI: 10.1371/JOURNAL.PONE.0071242
Page generated: Fri Aug 16 16:16:41 2024

Last articles

Fe in 2YXO
Fe in 2YRS
Fe in 2YXC
Fe in 2YNM
Fe in 2YVJ
Fe in 2YP1
Fe in 2YU2
Fe in 2YU1
Fe in 2YQB
Fe in 2YOO
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy