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Magnesium in PDB 4ia0: Crystal Structure of the PDE5A1 Catalytic Domain in Complex with Novel Inhibitors
Enzymatic activity of Crystal Structure of the PDE5A1 Catalytic Domain in Complex with Novel Inhibitors
All present enzymatic activity of Crystal Structure of the PDE5A1 Catalytic Domain in Complex with Novel Inhibitors:
3.1.4.35;
3.1.4.35;
Protein crystallography data
The structure of Crystal Structure of the PDE5A1 Catalytic Domain in Complex with Novel Inhibitors, PDB code: 4ia0
was solved by
J.Ren,
T.Chen,
Y.Xu,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 36.20 / 2.17 |
| Space group | P 31 2 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 74.430, 74.430, 131.260, 90.00, 90.00, 120.00 |
| R / Rfree (%) | 21.4 / 25.3 |
Other elements in 4ia0:
The structure of Crystal Structure of the PDE5A1 Catalytic Domain in Complex with Novel Inhibitors also contains other interesting chemical elements:
| Bromine | (Br) | 1 atom |
| Zinc | (Zn) | 1 atom |
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Crystal Structure of the PDE5A1 Catalytic Domain in Complex with Novel Inhibitors
(pdb code 4ia0). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Crystal Structure of the PDE5A1 Catalytic Domain in Complex with Novel Inhibitors, PDB code: 4ia0:
In total only one binding site of Magnesium was determined in the Crystal Structure of the PDE5A1 Catalytic Domain in Complex with Novel Inhibitors, PDB code: 4ia0:
Magnesium binding site 1 out of 1 in 4ia0
Go back to
Magnesium Binding Sites List in 4ia0
Magnesium binding site 1 out
of 1 in the Crystal Structure of the PDE5A1 Catalytic Domain in Complex with Novel Inhibitors
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Magnesium with other atoms in the Mg binding
site number 1 of Crystal Structure of the PDE5A1 Catalytic Domain in Complex with Novel Inhibitors within 5.0Å range:
|
Reference:
X.Gong,
G.Wang,
J.Ren,
Z.Liu,
Z.Wang,
T.Chen,
X.Yang,
X.Jiang,
J.Shen,
H.Jiang,
H.A.Aisa,
Y.Xu,
J.Li.
Exploration of the 5-Bromopyrimidin-4(3H)-Ones As Potent Inhibitors of PDE5. Bioorg.Med.Chem.Lett. V. 23 4944 2013.
ISSN: ISSN 0960-894X
PubMed: 23867165
DOI: 10.1016/J.BMCL.2013.06.062
Page generated: Mon Dec 14 18:52:25 2020
ISSN: ISSN 0960-894X
PubMed: 23867165
DOI: 10.1016/J.BMCL.2013.06.062
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