Magnesium in PDB 4ig8: Structural Basis For Cytosolic Double-Stranded Rna Surveillance By Human OAS1

The structure of Structural Basis For Cytosolic Double-Stranded Rna Surveillance By Human OAS1, PDB code: 4ig8 was solved by J.Donovan, A.Korennykh, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	67.70 / 2.70
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	71.200, 93.200, 98.600, 90.00, 90.00, 90.00
R / Rfree (%)	22.9 / 28.3

The binding sites of Magnesium atom in the Structural Basis For Cytosolic Double-Stranded Rna Surveillance By Human OAS1 (pdb code 4ig8). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Structural Basis For Cytosolic Double-Stranded Rna Surveillance By Human OAS1, PDB code: 4ig8:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Structural Basis For Cytosolic Double-Stranded Rna Surveillance By Human OAS1


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Structural Basis For Cytosolic Double-Stranded Rna Surveillance By Human OAS1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg401 b:90.6 occ:1.00 OD2 A:ASP148 2.2 76.3 1.0 O2A A:DTP403 2.6 0.1 1.0 OD2 A:ASP75 2.6 82.9 1.0 C5' A:DTP403 3.0 0.0 1.0 OD2 A:ASP77 3.0 72.3 1.0 PA A:DTP403 3.2 0.2 1.0 O1A A:DTP403 3.2 0.3 1.0 O5' A:DTP403 3.3 0.5 1.0 CG A:ASP148 3.4 76.0 1.0 O A:HOH501 3.5 60.2 1.0 CG A:ASP75 3.7 83.0 1.0 CG A:ASP77 4.0 70.6 1.0 C4' A:DTP403 4.1 0.4 1.0 C3' A:DTP403 4.1 0.8 1.0 CB A:ASP75 4.1 78.9 1.0 OD1 A:ASP77 4.2 71.0 1.0 OD1 A:ASP148 4.3 79.3 1.0 CB A:ASP148 4.3 72.1 1.0 O3' A:DTP403 4.4 0.6 1.0 MG A:MG402 4.4 81.7 1.0 OD1 A:ASP75 4.7 86.3 1.0 O3A A:DTP403 4.8 69.3 1.0

Magnesium binding site 2 out of 2 in the Structural Basis For Cytosolic Double-Stranded Rna Surveillance By Human OAS1


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Structural Basis For Cytosolic Double-Stranded Rna Surveillance By Human OAS1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg402 b:81.7 occ:1.00 OD1 A:ASP77 2.0 71.0 1.0 O1B A:DTP403 2.2 0.4 1.0 O1G A:DTP403 2.4 79.2 1.0 CB A:ASP75 2.7 78.9 1.0 O2A A:DTP403 3.0 0.1 1.0 CG A:ASP77 3.1 70.6 1.0 CA A:ASP75 3.4 77.5 1.0 N A:ASP75 3.4 78.4 1.0 OD2 A:ASP77 3.6 72.3 1.0 C A:ASP75 3.6 74.2 1.0 PB A:DTP403 3.6 69.8 1.0 O A:ASP75 3.7 72.7 1.0 PG A:DTP403 3.7 79.8 1.0 N A:SER63 3.8 63.3 1.0 PA A:DTP403 3.9 0.2 1.0 CG A:ASP75 3.9 83.0 1.0 O1A A:DTP403 4.0 0.3 1.0 CB A:SER63 4.0 67.3 1.0 OD2 A:ASP75 4.1 82.9 1.0 O3B A:DTP403 4.1 80.2 1.0 O3A A:DTP403 4.2 69.3 1.0 OG A:SER63 4.2 69.8 1.0 N A:ALA76 4.3 73.3 1.0 CB A:ASP77 4.3 68.3 1.0 O2G A:DTP403 4.3 81.3 1.0 MG A:MG401 4.4 90.6 1.0 N A:ASP77 4.5 68.4 1.0 CA A:SER63 4.6 64.5 1.0 C A:SER74 4.6 79.2 1.0 CA A:GLY62 4.6 61.1 1.0 O2B A:DTP403 4.7 67.0 1.0 C A:GLY62 4.7 61.3 1.0 CA A:ALA76 4.8 70.4 1.0 O3G A:DTP403 4.9 79.5 1.0 C A:ALA76 4.9 69.3 1.0

J.Donovan, M.Dufner, A.Korennykh. Structural Basis For Cytosolic Double-Stranded Rna Surveillance By Human Oligoadenylate Synthetase 1. Proc.Natl.Acad.Sci.Usa V. 110 1652 2013.
ISSN: ISSN 0027-8424
PubMed: 23319625
DOI: 10.1073/PNAS.1218528110