Magnesium in PDB 4itd: Structures of Dna Duplexes Containing O6-Carboxymethylguanine, A Lesion Associated with Gastrointestinal Cancer, Reveal A Mechanism For Inducing Transition Mutation

The structure of Structures of Dna Duplexes Containing O6-Carboxymethylguanine, A Lesion Associated with Gastrointestinal Cancer, Reveal A Mechanism For Inducing Transition Mutation, PDB code: 4itd was solved by F.Zhang, K.Suzuki, M.Tsunoda, O.Wilkinson, C.L.Millington, D.M.Williams, E.C.Morishita, A.Takenaka, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	34.41 / 1.94
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	25.051, 40.404, 65.667, 90.00, 90.00, 90.00
R / Rfree (%)	22.6 / 25.4

The binding sites of Magnesium atom in the Structures of Dna Duplexes Containing O6-Carboxymethylguanine, A Lesion Associated with Gastrointestinal Cancer, Reveal A Mechanism For Inducing Transition Mutation (pdb code 4itd). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Structures of Dna Duplexes Containing O6-Carboxymethylguanine, A Lesion Associated with Gastrointestinal Cancer, Reveal A Mechanism For Inducing Transition Mutation, PDB code: 4itd:

Magnesium binding site 1 out of 1 in the Structures of Dna Duplexes Containing O6-Carboxymethylguanine, A Lesion Associated with Gastrointestinal Cancer, Reveal A Mechanism For Inducing Transition Mutation


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Structures of Dna Duplexes Containing O6-Carboxymethylguanine, A Lesion Associated with Gastrointestinal Cancer, Reveal A Mechanism For Inducing Transition Mutation within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg101 b:31.8 occ:1.00 O A:HOH203 2.0 35.0 1.0 O A:HOH231 2.0 44.4 1.0 O A:HOH234 2.0 39.2 1.0 O A:HOH232 2.1 41.5 1.0 O A:HOH233 2.1 42.5 1.0 O B:HOH238 2.2 45.7 1.0 O A:HOH210 4.1 47.0 1.0 O B:HOH208 4.1 35.1 1.0 O B:HOH224 4.2 61.9 1.0 O6 B:DG22 4.3 33.5 1.0 O6 A:DG2 4.3 31.0 1.0 O B:HOH209 4.5 40.8 1.0 N7 A:DG2 4.5 28.9 1.0 O A:HOH229 4.6 40.0 1.0 O A:HOH222 4.7 37.5 1.0 C5 A:DC1 4.7 32.8 1.0 O B:HOH211 4.9 42.9 1.0 C6 A:DC1 4.9 34.9 1.0

F.Zhang, M.Tsunoda, K.Suzuki, Y.Kikuchi, O.Wilkinson, C.L.Millington, G.P.Margison, D.M.Williams, E.Czarina Morishita, A.Takenaka. Structures of Dna Duplexes Containing O6-Carboxymethylguanine, A Lesion Associated with Gastrointestinal Cancer, Reveal A Mechanism For Inducing Pyrimidine Transition Mutations Nucleic Acids Res. V. 41 5524 2013.
ISSN: ISSN 0305-1048
PubMed: 23580550
DOI: 10.1093/NAR/GKT198