Magnesium in PDB 4iwh: Crystal Structure of A 3-Isopropylmalate Dehydrogenase From Burkholderia Pseudomallei

All present enzymatic activity of Crystal Structure of A 3-Isopropylmalate Dehydrogenase From Burkholderia Pseudomallei:
1.1.1.85;

The structure of Crystal Structure of A 3-Isopropylmalate Dehydrogenase From Burkholderia Pseudomallei, PDB code: 4iwh was solved by Seattle Structural Genomics Center For Infectious Disease (Ssgcid), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.63 / 1.75
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	141.600, 60.100, 103.190, 90.00, 112.86, 90.00
R / Rfree (%)	16.8 / 20.1

The binding sites of Magnesium atom in the Crystal Structure of A 3-Isopropylmalate Dehydrogenase From Burkholderia Pseudomallei (pdb code 4iwh). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Crystal Structure of A 3-Isopropylmalate Dehydrogenase From Burkholderia Pseudomallei, PDB code: 4iwh:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Crystal Structure of A 3-Isopropylmalate Dehydrogenase From Burkholderia Pseudomallei


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of A 3-Isopropylmalate Dehydrogenase From Burkholderia Pseudomallei within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg401 b:21.3 occ:1.00 O A:HOH733 1.9 31.8 1.0 OD1 A:ASP246 2.0 18.5 1.0 OD2 B:ASP222 2.1 24.1 1.0 O B:HOH559 2.1 25.4 1.0 O A:HOH660 2.2 28.6 1.0 OD2 A:ASP250 2.2 21.1 1.0 CG A:ASP246 3.1 19.7 1.0 CG B:ASP222 3.1 23.2 1.0 CG A:ASP250 3.2 20.3 1.0 OD2 A:ASP246 3.5 21.2 1.0 CB B:ASP222 3.5 21.2 1.0 OD1 A:ASP250 3.6 22.6 1.0 O B:HOH649 4.1 39.0 1.0 O A:ASP246 4.2 16.5 1.0 OD1 B:ASP222 4.2 24.5 1.0 CB A:ASP246 4.4 18.0 1.0 O A:HOH809 4.5 38.1 1.0 CB A:ASP250 4.5 17.9 1.0 NZ B:LYS190 4.6 29.3 1.0 C A:ASP246 4.6 16.6 1.0 CA A:ASP246 4.7 17.1 1.0 NH1 A:ARG128 5.0 24.3 1.0

Magnesium binding site 2 out of 2 in the Crystal Structure of A 3-Isopropylmalate Dehydrogenase From Burkholderia Pseudomallei


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Crystal Structure of A 3-Isopropylmalate Dehydrogenase From Burkholderia Pseudomallei within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg401 b:27.2 occ:1.00 O A:HOH734 1.9 19.7 1.0 O B:HOH759 1.9 31.3 1.0 O B:HOH672 2.0 32.5 1.0 OD1 B:ASP246 2.2 20.5 1.0 OD2 A:ASP222 2.3 23.0 1.0 OD2 B:ASP250 2.3 19.4 1.0 O B:HOH757 2.7 29.0 1.0 CG A:ASP222 3.2 20.4 1.0 CG B:ASP250 3.3 19.3 1.0 CG B:ASP246 3.3 19.4 1.0 OD1 B:ASP250 3.6 20.9 1.0 CB A:ASP222 3.6 18.1 1.0 O A:HOH735 3.9 28.4 1.0 OD2 B:ASP246 3.9 22.4 1.0 O B:ASP246 4.1 15.3 1.0 NZ A:LYS190 4.3 25.2 1.0 O A:HOH808 4.3 46.0 1.0 OD1 A:ASP222 4.3 21.3 1.0 O B:HOH617 4.4 29.4 1.0 CB B:ASP246 4.5 16.6 1.0 CB B:ASP250 4.5 16.8 1.0 C B:ASP246 4.6 15.6 1.0 CA B:ASP246 4.7 15.6 1.0

T.E.Edwards, J.Abendroth, Seattle Structural Genomics Center For Infectious Disease(Ssgcid). Crystal Structure of A 3-Isopropylmalate Dehydrogenase From Burkholderia Pseudomallei To Be Published.