Atomistry » Magnesium » PDB 4j9k-4jj2 » 4ja9
Atomistry »
  Magnesium »
    PDB 4j9k-4jj2 »
      4ja9 »

Magnesium in PDB 4ja9: Rat PP5 Apo

Enzymatic activity of Rat PP5 Apo

All present enzymatic activity of Rat PP5 Apo:
3.1.3.16;

Protein crystallography data

The structure of Rat PP5 Apo, PDB code: 4ja9 was solved by V.Haslbeck, M.Helmuth, F.Alte, G.Popowicz, W.Schmidt, M.Weiwad, G.Fischer, G.Gemmecker, M.Sattler, F.Striggow, M.Groll, K.Richter, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 15.00 / 2.30
Space group P 41 21 2
Cell size a, b, c (Å), α, β, γ (°) 50.090, 50.090, 379.190, 90.00, 90.00, 90.00
R / Rfree (%) 23.8 / 27.2

Magnesium Binding Sites:

The binding sites of Magnesium atom in the Rat PP5 Apo (pdb code 4ja9). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Rat PP5 Apo, PDB code: 4ja9:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in 4ja9

Go back to Magnesium Binding Sites List in 4ja9
Magnesium binding site 1 out of 2 in the Rat PP5 Apo


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Rat PP5 Apo within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mg501

b:55.4
occ:1.00
MG A:MG502 2.1 58.0 1.0
OD2 A:ASP271 2.2 51.3 1.0
OD2 A:ASP242 2.3 53.8 1.0
O A:HOH602 2.5 51.9 1.0
NE2 A:HIS244 3.2 49.3 1.0
O A:HIS427 3.2 57.5 1.0
CG A:ASP271 3.4 53.9 1.0
CG A:ASP242 3.6 59.0 1.0
C A:HIS427 3.9 55.4 1.0
CA A:HIS427 3.9 52.8 1.0
NE2 A:HIS352 4.0 45.2 1.0
CE1 A:HIS244 4.1 50.7 1.0
CD2 A:HIS244 4.2 51.2 1.0
ND1 A:HIS427 4.2 52.5 1.0
CB A:ASP271 4.2 49.9 1.0
O A:HOH624 4.3 71.1 1.0
CE1 A:HIS352 4.3 45.9 1.0
OE1 A:GLU76 4.3 76.4 1.0
OD1 A:ASP271 4.3 53.3 1.0
OD1 A:ASP242 4.3 63.8 1.0
OD1 A:ASN303 4.4 53.7 1.0
CB A:ASP242 4.5 58.8 1.0
CD2 A:HIS304 4.7 48.2 1.0
N A:HIS427 4.7 54.0 1.0
CE1 A:PHE446 4.7 45.0 1.0
OH A:TYR451 4.9 54.4 1.0
CG A:HIS427 5.0 50.6 1.0
CE1 A:HIS427 5.0 54.4 1.0

Magnesium binding site 2 out of 2 in 4ja9

Go back to Magnesium Binding Sites List in 4ja9
Magnesium binding site 2 out of 2 in the Rat PP5 Apo


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Rat PP5 Apo within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mg502

b:58.0
occ:1.00
MG A:MG501 2.1 55.4 1.0
OD2 A:ASP271 2.3 51.3 1.0
OD1 A:ASN303 2.5 53.7 1.0
O A:HOH602 2.5 51.9 1.0
NE2 A:HIS352 2.7 45.2 1.0
ND1 A:HIS427 2.7 52.5 1.0
CG A:ASP271 3.2 53.9 1.0
CG A:ASN303 3.3 53.1 1.0
CE1 A:HIS427 3.4 54.4 1.0
OD1 A:ASP271 3.4 53.3 1.0
ND2 A:ASN303 3.5 56.2 1.0
CE1 A:HIS352 3.5 45.9 1.0
OD2 A:ASP242 3.6 53.8 1.0
CD2 A:HIS352 3.8 47.2 1.0
O A:HIS427 3.8 57.5 1.0
CA A:HIS427 3.8 52.8 1.0
CG A:HIS427 3.9 50.6 1.0
CD2 A:HIS304 4.2 48.2 1.0
C A:HIS427 4.3 55.4 1.0
CB A:HIS427 4.3 49.6 1.0
CB A:ASP271 4.5 49.9 1.0
NE2 A:HIS244 4.6 49.3 1.0
NE2 A:HIS427 4.6 53.7 1.0
CG A:ASP242 4.7 59.0 1.0
ND1 A:HIS352 4.7 45.5 1.0
NH1 A:ARG400 4.7 60.1 1.0
CB A:ASN303 4.8 52.2 1.0
CG A:HIS352 4.9 49.0 1.0
N A:HIS427 4.9 54.0 1.0
CD2 A:HIS427 4.9 49.5 1.0
NE2 A:HIS304 4.9 48.4 1.0

Reference:

V.Haslbeck, M.Helmuth, F.Alte, G.Popowicz, W.Schmidt, M.Weiwad, G.Fischer, G.Gemmecker, M.Sattler, F.Striggow, M.Groll, K.Richter. Selective Targeting of the Autoinhibition of PP5 Reduces Tau Phosphorylation in Mouse. To Be Published.
Page generated: Mon Dec 14 18:56:13 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy