Magnesium in PDB 4jsp: Structure of Mtordeltan-MLST8-Atpgammas-Mg Complex

All present enzymatic activity of Structure of Mtordeltan-MLST8-Atpgammas-Mg Complex:
2.7.11.1;

The structure of Structure of Mtordeltan-MLST8-Atpgammas-Mg Complex, PDB code: 4jsp was solved by N.P.Pavletich, H.Yang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	100.00 / 3.30
Space group	P 2 21 21
Cell size a, b, c (Å), α, β, γ (°)	139.400, 163.200, 207.800, 90.00, 90.00, 90.00
R / Rfree (%)	23.3 / 26.8

The binding sites of Magnesium atom in the Structure of Mtordeltan-MLST8-Atpgammas-Mg Complex (pdb code 4jsp). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 4 binding sites of Magnesium where determined in the Structure of Mtordeltan-MLST8-Atpgammas-Mg Complex, PDB code: 4jsp:
Jump to Magnesium binding site number: 1; 2; 3; 4;

Magnesium binding site 1 out of 4 in the Structure of Mtordeltan-MLST8-Atpgammas-Mg Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Structure of Mtordeltan-MLST8-Atpgammas-Mg Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg3001 b:63.2 occ:1.00 O2G B:AGS3000 2.2 74.9 1.0 O1A B:AGS3000 2.8 68.5 1.0 OD1 B:ASN2343 2.9 50.7 1.0 PG B:AGS3000 3.1 82.1 1.0 O3B B:AGS3000 3.2 76.4 1.0 OD2 B:ASP2357 3.4 50.8 1.0 O3G B:AGS3000 3.5 77.2 1.0 MG B:MG3002 3.6 69.8 1.0 CB B:ASP2357 3.9 41.4 1.0 CG B:ASN2343 4.0 43.8 1.0 CG B:ASP2357 4.1 44.5 1.0 CD1 B:ILE2356 4.1 34.1 1.0 PA B:AGS3000 4.2 71.3 1.0 ND2 B:ASN2343 4.5 43.4 1.0 PB B:AGS3000 4.6 78.8 1.0 O5' B:AGS3000 4.7 67.1 1.0 O B:SER2342 4.7 36.7 1.0 O3A B:AGS3000 4.9 74.7 1.0 O1B B:AGS3000 4.9 79.0 1.0 CE1 B:HIS2340 5.0 38.2 1.0

Magnesium binding site 2 out of 4 in the Structure of Mtordeltan-MLST8-Atpgammas-Mg Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Structure of Mtordeltan-MLST8-Atpgammas-Mg Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg3002 b:69.8 occ:1.00 O3G B:AGS3000 2.2 77.2 1.0 OD2 B:ASP2357 3.2 50.8 1.0 OE1 B:GLU2190 3.2 77.6 1.0 PG B:AGS3000 3.4 82.1 1.0 O1B B:AGS3000 3.4 79.0 1.0 MG B:MG3001 3.6 63.2 1.0 CD B:GLU2190 3.7 77.2 1.0 O3B B:AGS3000 3.9 76.4 1.0 O2G B:AGS3000 3.9 74.9 1.0 CG B:ASP2357 4.1 44.5 1.0 OE2 B:GLU2190 4.1 77.9 1.0 NZ B:LYS2187 4.2 51.7 1.0 OE1 B:GLN2167 4.2 83.1 1.0 NE2 B:GLN2167 4.3 80.6 1.0 O1A B:AGS3000 4.3 68.5 1.0 PB B:AGS3000 4.3 78.8 1.0 CG B:GLU2190 4.6 75.1 1.0 OD1 B:ASP2357 4.7 44.3 1.0 CD B:GLN2167 4.7 81.5 1.0 CB B:ASP2357 4.9 41.4 1.0

Magnesium binding site 3 out of 4 in the Structure of Mtordeltan-MLST8-Atpgammas-Mg Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of Structure of Mtordeltan-MLST8-Atpgammas-Mg Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg3001 b:66.0 occ:1.00 O2G A:AGS3000 1.8 78.3 1.0 O1A A:AGS3000 2.8 71.5 1.0 PG A:AGS3000 3.1 85.9 1.0 OD1 A:ASN2343 3.2 54.0 1.0 O3B A:AGS3000 3.2 79.0 1.0 MG A:MG3002 4.0 72.3 1.0 O3G A:AGS3000 4.0 80.9 1.0 PA A:AGS3000 4.2 72.7 1.0 O A:SER2342 4.2 42.1 1.0 OD2 A:ASP2357 4.3 53.6 1.0 CD1 A:ILE2356 4.3 38.1 1.0 CG A:ASN2343 4.3 47.7 1.0 O5' A:AGS3000 4.5 69.6 1.0 PB A:AGS3000 4.5 80.8 1.0 O1B A:AGS3000 4.5 81.0 1.0 S1G A:AGS3000 4.6 84.6 1.0 CE1 A:HIS2340 4.7 43.2 1.0 CB A:ASP2357 4.8 44.8 1.0 C A:SER2342 4.9 42.3 1.0 ND2 A:ASN2343 4.9 48.0 1.0 O3A A:AGS3000 4.9 75.8 1.0 NE2 A:HIS2340 4.9 43.7 1.0 CB A:SER2342 5.0 41.7 1.0

Magnesium binding site 4 out of 4 in the Structure of Mtordeltan-MLST8-Atpgammas-Mg Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 4 of Structure of Mtordeltan-MLST8-Atpgammas-Mg Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg3002 b:72.3 occ:1.00 O3G A:AGS3000 2.5 80.9 1.0 O1B A:AGS3000 2.9 81.0 1.0 OD2 A:ASP2357 3.3 53.6 1.0 O2G A:AGS3000 3.4 78.3 1.0 PG A:AGS3000 3.4 85.9 1.0 OE1 A:GLU2190 3.6 94.9 1.0 O3B A:AGS3000 3.9 79.0 1.0 MG A:MG3001 4.0 66.0 1.0 PB A:AGS3000 4.0 80.8 1.0 O1A A:AGS3000 4.1 71.5 1.0 CD A:GLU2190 4.1 95.5 1.0 CG A:ASP2357 4.1 47.6 1.0 NE2 A:GLN2167 4.2 89.3 1.0 NZ A:LYS2187 4.3 71.1 1.0 OE2 A:GLU2190 4.4 96.2 1.0 OE1 A:GLN2167 4.4 92.4 1.0 CD A:GLN2167 4.8 91.0 1.0 CB A:ASP2357 4.8 44.8 1.0 OD1 A:ASP2357 4.9 47.2 1.0 O2B A:AGS3000 5.0 81.7 1.0

H.Yang, D.G.Rudge, J.D.Koos, B.Vaidialingam, H.J.Yang, N.P.Pavletich. Mtor Kinase Structure, Mechanism and Regulation. Nature V. 497 217 2013.
ISSN: ISSN 0028-0836
PubMed: 23636326
DOI: 10.1038/NATURE12122