Magnesium in PDB 4kb6: Structure of Porcine Cyclic Gmp Amp Synthase (Cgas) in Complex with Dna, Atp and Gtp

The structure of Structure of Porcine Cyclic Gmp Amp Synthase (Cgas) in Complex with Dna, Atp and Gtp, PDB code: 4kb6 was solved by T.Deimling, K.-P.Hopfner, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	68.33 / 3.08
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	86.280, 111.890, 117.780, 90.00, 90.00, 90.00
R / Rfree (%)	25.5 / 25.8

The structure of Structure of Porcine Cyclic Gmp Amp Synthase (Cgas) in Complex with Dna, Atp and Gtp also contains other interesting chemical elements:

Zinc

(Zn)

1 atom

The binding sites of Magnesium atom in the Structure of Porcine Cyclic Gmp Amp Synthase (Cgas) in Complex with Dna, Atp and Gtp (pdb code 4kb6). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Structure of Porcine Cyclic Gmp Amp Synthase (Cgas) in Complex with Dna, Atp and Gtp, PDB code: 4kb6:

Magnesium binding site 1 out of 1 in the Structure of Porcine Cyclic Gmp Amp Synthase (Cgas) in Complex with Dna, Atp and Gtp


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Structure of Porcine Cyclic Gmp Amp Synthase (Cgas) in Complex with Dna, Atp and Gtp within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg504 b:0.5 occ:1.00 OD1 A:ASN202 2.1 1.0 1.0 O3B A:ATP503 2.3 0.4 1.0 OE1 A:GLN200 2.5 0.7 1.0 OG A:SER188 2.8 0.2 1.0 O3A A:ATP503 2.8 0.7 1.0 PB A:ATP503 2.9 0.2 1.0 CG A:ASN202 3.0 0.2 1.0 ND2 A:ASN202 3.3 0.1 1.0 PG A:ATP503 3.4 0.0 1.0 O2B A:ATP503 3.5 0.7 1.0 O3G A:ATP503 3.5 0.9 1.0 N A:SER188 3.7 0.5 1.0 CD A:GLN200 3.7 0.5 1.0 CB A:SER188 3.9 0.0 1.0 O1G A:ATP503 4.1 0.6 1.0 O A:GLN200 4.2 81.9 1.0 PA A:ATP503 4.3 0.7 1.0 CA A:SER188 4.3 94.9 1.0 O1B A:ATP503 4.4 0.4 1.0 C A:GLY187 4.4 0.7 1.0 CB A:ASN202 4.4 0.9 1.0 N A:ASN202 4.4 0.7 1.0 CA A:GLY187 4.5 0.3 1.0 CG A:GLN200 4.5 0.7 1.0 C A:GLN200 4.6 90.7 1.0 N A:TYR189 4.6 81.4 1.0 C A:PHE201 4.7 99.4 1.0 NE2 A:GLN200 4.7 0.2 1.0 O2G A:ATP503 4.7 0.5 1.0 CB A:GLN200 4.7 94.6 1.0 O2A A:ATP503 4.7 0.0 1.0 CA A:PHE201 4.8 89.8 1.0 C5' A:ATP503 4.9 0.6 1.0 N A:PHE201 4.9 95.3 1.0

F.Civril, T.Deimling, C.C.De Oliveira Mann, A.Ablasser, M.Moldt, G.Witte, V.Hornung, K.P.Hopfner. Structural Mechanism of Cytosolic Dna Sensing By Cgas. Nature V. 498 332 2013.
ISSN: ISSN 0028-0836
PubMed: 23722159
DOI: 10.1038/NATURE12305