Magnesium in PDB 4klz: Inhibition of Small Gtpases By Stabilization of the Gdp Complex, A Novel Approach Applied to RIT1, A Target For Rheumatoid Arthritis

The structure of Inhibition of Small Gtpases By Stabilization of the Gdp Complex, A Novel Approach Applied to RIT1, A Target For Rheumatoid Arthritis, PDB code: 4klz was solved by D.M.Shah, M.Kobayashi, P.H.Keizers, A.W.Tuin, E.Ab, L.Manning, A.A.Rzepiela, M.Andrews, F.J.Hoedemaeker, G.Siegal, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	40.50 / 2.30
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	40.278, 37.048, 40.736, 90.00, 95.90, 90.00
R / Rfree (%)	18.5 / 31.1

The binding sites of Magnesium atom in the Inhibition of Small Gtpases By Stabilization of the Gdp Complex, A Novel Approach Applied to RIT1, A Target For Rheumatoid Arthritis (pdb code 4klz). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Inhibition of Small Gtpases By Stabilization of the Gdp Complex, A Novel Approach Applied to RIT1, A Target For Rheumatoid Arthritis, PDB code: 4klz:

Magnesium binding site 1 out of 1 in the Inhibition of Small Gtpases By Stabilization of the Gdp Complex, A Novel Approach Applied to RIT1, A Target For Rheumatoid Arthritis


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Inhibition of Small Gtpases By Stabilization of the Gdp Complex, A Novel Approach Applied to RIT1, A Target For Rheumatoid Arthritis within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg502 b:19.4 occ:1.00 O2B A:GDP501 2.0 12.1 1.0 O A:HOH618 2.2 12.0 1.0 OG A:SER35 2.4 7.9 1.0 PB A:GDP501 3.1 11.0 1.0 CB A:SER35 3.2 8.8 1.0 O3B A:GDP501 3.4 8.5 1.0 O1A A:GDP501 3.8 9.2 1.0 CD2 A:HIS50 3.9 34.2 1.0 O3A A:GDP501 4.1 5.9 1.0 O1B A:GDP501 4.1 10.3 1.0 N A:SER35 4.2 11.9 1.0 OD2 A:ASP75 4.2 12.9 1.0 CA A:SER35 4.3 9.9 1.0 PA A:GDP501 4.3 11.9 1.0 NE2 A:HIS50 4.3 34.5 1.0 O A:PRO52 4.4 22.2 1.0 O2A A:GDP501 4.5 8.9 1.0 OD1 A:ASP75 4.5 14.7 1.0 O A:HOH605 4.6 6.0 1.0 O A:THR76 4.7 18.4 1.0 CA A:PRO52 4.8 21.7 1.0 CG A:ASP75 4.8 13.7 1.0 NZ A:LYS34 5.0 7.3 1.0 CE A:LYS34 5.0 6.9 1.0 C A:PRO52 5.0 23.5 1.0

D.M.Shah, M.Kobayashi, P.H.Keizers, A.W.Tuin, E.Ab, L.Manning, A.A.Rzepiela, M.Andrews, F.J.Hoedemaeker, G.Siegal. Inhibition of Small Gtpases By Stabilization of the Gdp Complex, A Novel Approach Applied to RIT1, A Target For Rheumatoid Arthritis To Be Published.