Magnesium in PDB 4kva: Gtpase Domain of Septin 10 From Schistosoma Mansoni in Complex with Gtp

The structure of Gtpase Domain of Septin 10 From Schistosoma Mansoni in Complex with Gtp, PDB code: 4kva was solved by A.E.Zeraik, H.M.Pereira, Y.V.Santos, J.Brandao-Neto, R.C.Garratt, A.P.U.Araujo, R.Demarco, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	74.22 / 2.14
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	160.800, 47.040, 95.480, 90.00, 112.61, 90.00
R / Rfree (%)	18.7 / 22.1

The binding sites of Magnesium atom in the Gtpase Domain of Septin 10 From Schistosoma Mansoni in Complex with Gtp (pdb code 4kva). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Gtpase Domain of Septin 10 From Schistosoma Mansoni in Complex with Gtp, PDB code: 4kva:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Gtpase Domain of Septin 10 From Schistosoma Mansoni in Complex with Gtp


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Gtpase Domain of Septin 10 From Schistosoma Mansoni in Complex with Gtp within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg501 b:41.6 occ:1.00 O1G A:GTP500 2.1 46.3 1.0 OG A:SER55 2.1 36.6 1.0 OE2 A:GLU100 2.1 53.6 1.0 O1B A:GTP500 2.1 27.4 1.0 O A:HOH690 2.1 37.9 1.0 O A:HOH691 2.2 34.2 1.0 CD A:GLU100 3.1 56.3 1.0 CB A:SER55 3.2 30.5 1.0 PG A:GTP500 3.3 43.2 1.0 PB A:GTP500 3.4 30.5 1.0 OE1 A:GLU100 3.5 60.6 1.0 O3B A:GTP500 3.7 35.9 1.0 O1A A:GTP500 3.8 39.5 1.0 N A:SER55 3.9 22.9 1.0 O3G A:GTP500 3.9 40.9 1.0 O A:HOH664 4.0 48.7 1.0 CA A:SER55 4.1 27.7 1.0 O2B A:GTP500 4.2 26.6 1.0 CG A:GLU100 4.4 51.2 1.0 O3A A:GTP500 4.5 29.8 1.0 O2G A:GTP500 4.5 40.1 1.0 PA A:GTP500 4.6 33.0 1.0 O2A A:GTP500 4.8 35.6 1.0 CB A:LYS54 4.8 27.3 1.0 C A:LYS54 5.0 25.4 1.0 CE A:LYS54 5.0 28.5 1.0

Magnesium binding site 2 out of 2 in the Gtpase Domain of Septin 10 From Schistosoma Mansoni in Complex with Gtp


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Gtpase Domain of Septin 10 From Schistosoma Mansoni in Complex with Gtp within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg501 b:37.1 occ:1.00 O1G B:GTP500 2.1 45.6 1.0 O1B B:GTP500 2.1 27.1 1.0 OG B:SER55 2.1 34.1 1.0 O B:HOH699 2.1 29.7 1.0 O B:HOH610 2.3 33.6 1.0 OE2 B:GLU100 2.4 48.2 1.0 CB B:SER55 3.2 36.7 1.0 PG B:GTP500 3.3 41.1 1.0 CD B:GLU100 3.3 46.7 1.0 PB B:GTP500 3.4 29.9 1.0 OE1 B:GLU100 3.5 46.0 1.0 O3B B:GTP500 3.7 40.7 1.0 N B:SER55 3.8 27.7 1.0 O3G B:GTP500 3.9 44.6 1.0 O1A B:GTP500 3.9 26.6 1.0 O B:HOH637 4.0 46.2 1.0 CA B:SER55 4.0 40.4 1.0 O2B B:GTP500 4.3 23.3 1.0 O3A B:GTP500 4.5 34.0 1.0 O2G B:GTP500 4.5 53.0 1.0 PA B:GTP500 4.6 30.1 1.0 CB B:LYS54 4.7 28.8 1.0 CG B:GLU100 4.7 38.0 1.0 CE B:LYS54 4.8 27.2 1.0 O2A B:GTP500 4.8 33.3 1.0 C B:LYS54 4.9 30.9 1.0

A.E.Zeraik, H.M.Pereira, Y.V.Santos, J.Brandao-Neto, M.Spoerner, M.S.Santos, L.A.Colnago, R.C.Garratt, A.P.Araujo, R.Demarco. Crystal Structure of A Schistosoma Mansoni Septin Reveals the Phenomenon of Strand Slippage in Septins Dependent on the Nature of the Bound Nucleotide. J.Biol.Chem. V. 289 7799 2014.
ISSN: ISSN 0021-9258
PubMed: 24464615
DOI: 10.1074/JBC.M113.525352