Magnesium in PDB 4l7w: Crystal Structure Mutant H77A of Human Hd Domain-Containing Protein 2, Genomics Consortium (Nesg) Target HR6723

The structure of Crystal Structure Mutant H77A of Human Hd Domain-Containing Protein 2, Genomics Consortium (Nesg) Target HR6723, PDB code: 4l7w was solved by A.Kuzin, M.Su, A.Yakunin, N.Beloglazova, J.Seetharaman, M.Maglaqui, R.Xiao, D.Lee, G.Brown, R.Flick, J.K.Everett, T.B.Acton, G.T.Montelione, J.F.Hunt, L.Tong, Northeast Structural Genomics Consortium (Nesg), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	35.69 / 2.31
Space group	I 41 2 2
Cell size a, b, c (Å), α, β, γ (°)	71.380, 71.380, 199.308, 90.00, 90.00, 90.00
R / Rfree (%)	17.4 / 22.8

The binding sites of Magnesium atom in the Crystal Structure Mutant H77A of Human Hd Domain-Containing Protein 2, Genomics Consortium (Nesg) Target HR6723 (pdb code 4l7w). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 5 binding sites of Magnesium where determined in the Crystal Structure Mutant H77A of Human Hd Domain-Containing Protein 2, Genomics Consortium (Nesg) Target HR6723, PDB code: 4l7w:
Jump to Magnesium binding site number: 1; 2; 3; 4; 5;

Magnesium binding site 1 out of 5 in the Crystal Structure Mutant H77A of Human Hd Domain-Containing Protein 2, Genomics Consortium (Nesg) Target HR6723


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure Mutant H77A of Human Hd Domain-Containing Protein 2, Genomics Consortium (Nesg) Target HR6723 within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg301 b:43.1 occ:1.00 OD1 A:ASP86 2.1 41.4 1.0 MG A:MG304 2.1 53.9 1.0 OE2 A:GLU81 2.2 48.4 1.0 MG A:MG303 2.3 55.1 1.0 MG A:MG305 2.3 57.0 1.0 MG A:MG302 2.3 58.6 1.0 CD A:GLU81 3.1 46.3 1.0 CG A:ASP86 3.1 41.4 1.0 OE1 A:GLU81 3.3 43.4 1.0 OD2 A:ASP86 3.8 44.9 1.0 O A:ILE87 4.1 45.2 1.0 O A:HOH421 4.1 47.0 1.0 CB A:ASP86 4.1 35.1 1.0 O A:HOH414 4.1 41.8 1.0 NH1 A:ARG32 4.1 41.1 1.0 OD2 A:ASP78 4.1 40.1 1.0 CA A:ASP86 4.2 38.1 1.0 O A:HOH433 4.2 58.5 1.0 OD1 A:ASP78 4.3 41.4 1.0 CG A:ASP78 4.3 41.2 1.0 N A:ILE87 4.4 44.5 1.0 CG A:GLU81 4.4 41.3 1.0 C A:ASP86 4.5 40.9 1.0 O A:HOH411 4.8 42.4 1.0 C A:ILE87 5.0 44.6 1.0

Magnesium binding site 2 out of 5 in the Crystal Structure Mutant H77A of Human Hd Domain-Containing Protein 2, Genomics Consortium (Nesg) Target HR6723


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Crystal Structure Mutant H77A of Human Hd Domain-Containing Protein 2, Genomics Consortium (Nesg) Target HR6723 within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg302 b:58.6 occ:1.00 MG A:MG301 2.3 43.1 1.0 O A:HOH433 2.7 58.5 1.0 MG A:MG305 2.8 57.0 1.0 NH1 A:ARG32 3.1 41.1 1.0 OD1 A:ASP86 3.2 41.4 1.0 MG A:MG304 3.3 53.9 1.0 MG A:MG303 3.4 55.1 1.0 O A:HOH411 3.8 42.4 1.0 O A:HOH410 3.9 38.6 1.0 CG A:ASP86 4.1 41.4 1.0 O A:ILE87 4.2 45.2 1.0 OD2 A:ASP86 4.2 44.9 1.0 CZ A:ARG32 4.4 37.8 1.0 OE2 A:GLU81 4.4 48.4 1.0 O A:HOH438 4.5 59.9 1.0 OD2 A:ASP78 4.9 40.1 1.0 NH2 A:ARG32 5.0 35.0 1.0

Magnesium binding site 3 out of 5 in the Crystal Structure Mutant H77A of Human Hd Domain-Containing Protein 2, Genomics Consortium (Nesg) Target HR6723


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of Crystal Structure Mutant H77A of Human Hd Domain-Containing Protein 2, Genomics Consortium (Nesg) Target HR6723 within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg303 b:55.1 occ:1.00 MG A:MG301 2.3 43.1 1.0 OE1 A:GLU81 2.5 43.4 1.0 OD2 A:ASP78 2.7 40.1 1.0 OE2 A:GLU81 2.9 48.4 1.0 MG A:MG305 3.0 57.0 1.0 OD1 A:ASP86 3.0 41.4 1.0 CD A:GLU81 3.0 46.3 1.0 NH1 A:ARG32 3.1 41.1 1.0 CG A:ASP86 3.3 41.4 1.0 CG A:ASP78 3.3 41.2 1.0 MG A:MG302 3.4 58.6 1.0 OD2 A:ASP86 3.5 44.9 1.0 CD A:ARG32 3.7 32.1 1.0 OD1 A:ASP78 3.9 41.4 1.0 CB A:ASP78 4.1 43.8 1.0 CG1 A:VAL46 4.1 35.7 1.0 CZ A:ARG32 4.1 37.8 1.0 CB A:ASP86 4.2 35.1 1.0 CG2 A:VAL46 4.2 35.0 1.0 MG A:MG304 4.3 53.9 1.0 NE A:ARG32 4.4 34.9 1.0 CD2 A:HIS49 4.5 37.3 1.0 CG A:GLU81 4.5 41.3 1.0 CB A:VAL46 4.7 39.9 1.0 O A:HOH433 4.8 58.5 1.0 CA A:ASP86 4.9 38.1 1.0 O A:HOH411 4.9 42.4 1.0

Magnesium binding site 4 out of 5 in the Crystal Structure Mutant H77A of Human Hd Domain-Containing Protein 2, Genomics Consortium (Nesg) Target HR6723


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 4 of Crystal Structure Mutant H77A of Human Hd Domain-Containing Protein 2, Genomics Consortium (Nesg) Target HR6723 within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg304 b:53.9 occ:1.00 MG A:MG301 2.1 43.1 1.0 O A:ILE87 2.7 45.2 1.0 OE2 A:GLU81 3.0 48.4 1.0 OD1 A:ASP86 3.0 41.4 1.0 O A:HOH414 3.1 41.8 1.0 MG A:MG305 3.2 57.0 1.0 MG A:MG302 3.3 58.6 1.0 N A:ILE87 3.4 44.5 1.0 NZ A:LYS98 3.6 56.2 1.0 CE A:LYS98 3.6 60.9 1.0 O A:HOH421 3.7 47.0 1.0 C A:ILE87 3.7 44.6 1.0 CA A:ILE87 4.0 47.3 1.0 CD A:GLU81 4.0 46.3 1.0 C A:ASP86 4.1 40.9 1.0 CG A:ASP86 4.2 41.4 1.0 CB A:ILE87 4.2 51.7 1.0 MG A:MG303 4.3 55.1 1.0 CA A:ASP86 4.4 38.1 1.0 OE1 A:GLU81 4.7 43.4 1.0 CG A:GLU81 4.9 41.3 1.0 N A:ALA88 4.9 42.5 1.0 CB A:ASP86 4.9 35.1 1.0 O A:HOH433 4.9 58.5 1.0

Magnesium binding site 5 out of 5 in the Crystal Structure Mutant H77A of Human Hd Domain-Containing Protein 2, Genomics Consortium (Nesg) Target HR6723


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 5 of Crystal Structure Mutant H77A of Human Hd Domain-Containing Protein 2, Genomics Consortium (Nesg) Target HR6723 within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg305 b:57.0 occ:1.00 MG A:MG301 2.3 43.1 1.0 OD1 A:ASP78 2.7 41.4 1.0 MG A:MG302 2.8 58.6 1.0 OE2 A:GLU81 3.0 48.4 1.0 O A:HOH433 3.0 58.5 1.0 MG A:MG303 3.0 55.1 1.0 OD2 A:ASP78 3.1 40.1 1.0 CG A:ASP78 3.2 41.2 1.0 MG A:MG304 3.2 53.9 1.0 O A:HOH421 3.5 47.0 1.0 O A:HOH425 3.8 49.6 1.0 CD A:GLU81 4.0 46.3 1.0 OD1 A:ASP86 4.3 41.4 1.0 NH1 A:ARG32 4.3 41.1 1.0 OE1 A:GLU81 4.5 43.4 1.0 CB A:ASP78 4.6 43.8 1.0

A.Kuzin, M.Su, A.Yakunin, N.Beloglazova, J.Seetharaman, M.Maglaqui, R.Xiao, D.Lee, G.Brown, R.Flick, J.K.Everett, T.B.Acton, G.T.Montelione, J.F.Hunt, L.Tong, Northeast Structural Genomics Consortium (Nesg). Northeast Structural Genomics Consortium Target HR6723 To Be Published.