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Atomistry » Magnesium » PDB 4lj9-4lse » 4lmn | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Magnesium » PDB 4lj9-4lse » 4lmn » |
Magnesium in PDB 4lmn: Crystal Structure of MEK1 Kinase Bound to GDC0973Enzymatic activity of Crystal Structure of MEK1 Kinase Bound to GDC0973
All present enzymatic activity of Crystal Structure of MEK1 Kinase Bound to GDC0973:
2.7.12.2; Protein crystallography data
The structure of Crystal Structure of MEK1 Kinase Bound to GDC0973, PDB code: 4lmn
was solved by
M.H.Ultsch,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4lmn:
The structure of Crystal Structure of MEK1 Kinase Bound to GDC0973 also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Crystal Structure of MEK1 Kinase Bound to GDC0973
(pdb code 4lmn). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Crystal Structure of MEK1 Kinase Bound to GDC0973, PDB code: 4lmn: Magnesium binding site 1 out of 1 in 4lmnGo back to Magnesium Binding Sites List in 4lmn
Magnesium binding site 1 out
of 1 in the Crystal Structure of MEK1 Kinase Bound to GDC0973
Mono view Stereo pair view
Reference:
G.Hatzivassiliou,
J.R.Haling,
H.Chen,
K.Song,
S.Price,
R.Heald,
J.F.Hewitt,
M.Zak,
A.Peck,
C.Orr,
M.Merchant,
K.P.Hoeflich,
J.Chan,
S.M.Luoh,
D.J.Anderson,
M.J.Ludlam,
C.Wiesmann,
M.Ultsch,
L.S.Friedman,
S.Malek,
M.Belvin.
Mechanism of Mek Inhibition Determines Efficacy in Mutant Kras- Versus Braf-Driven Cancers. Nature V. 501 232 2013.
Page generated: Mon Dec 14 19:09:45 2020
ISSN: ISSN 0028-0836 PubMed: 23934108 DOI: 10.1038/NATURE12441 |
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