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Atomistry » Magnesium » PDB 4m3n-4mfe » 4m4q | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Magnesium » PDB 4m3n-4mfe » 4m4q » |
Magnesium in PDB 4m4q: 6-(4-Fluorophenyl)-3-Hydroxy-5-[4-(1H-1,2,3,4-Tetrazol-5-Yl)Phenyl] - 1,2-Dihydropyridin-2-One Bound to Influenza 2009 H1N1 EndonucleaseProtein crystallography data
The structure of 6-(4-Fluorophenyl)-3-Hydroxy-5-[4-(1H-1,2,3,4-Tetrazol-5-Yl)Phenyl] - 1,2-Dihydropyridin-2-One Bound to Influenza 2009 H1N1 Endonuclease, PDB code: 4m4q
was solved by
J.D.Bauman,
D.Patel,
K.Das,
E.Arnold,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4m4q:
The structure of 6-(4-Fluorophenyl)-3-Hydroxy-5-[4-(1H-1,2,3,4-Tetrazol-5-Yl)Phenyl] - 1,2-Dihydropyridin-2-One Bound to Influenza 2009 H1N1 Endonuclease also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the 6-(4-Fluorophenyl)-3-Hydroxy-5-[4-(1H-1,2,3,4-Tetrazol-5-Yl)Phenyl] - 1,2-Dihydropyridin-2-One Bound to Influenza 2009 H1N1 Endonuclease
(pdb code 4m4q). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the 6-(4-Fluorophenyl)-3-Hydroxy-5-[4-(1H-1,2,3,4-Tetrazol-5-Yl)Phenyl] - 1,2-Dihydropyridin-2-One Bound to Influenza 2009 H1N1 Endonuclease, PDB code: 4m4q: Magnesium binding site 1 out of 1 in 4m4qGo back to![]() ![]()
Magnesium binding site 1 out
of 1 in the 6-(4-Fluorophenyl)-3-Hydroxy-5-[4-(1H-1,2,3,4-Tetrazol-5-Yl)Phenyl] - 1,2-Dihydropyridin-2-One Bound to Influenza 2009 H1N1 Endonuclease
![]() Mono view ![]() Stereo pair view
Reference:
J.D.Bauman,
D.Patel,
S.F.Baker,
R.S.Vijayan,
A.Xiang,
A.K.Parhi,
L.Martinez-Sobrido,
E.J.Lavoie,
K.Das,
E.Arnold.
Crystallographic Fragment Screening and Structure-Based Optimization Yields A New Class of Influenza Endonuclease Inhibitors. Acs Chem.Biol. V. 8 2501 2013.
Page generated: Mon Aug 19 20:18:02 2024
ISSN: ISSN 1554-8929 PubMed: 23978130 DOI: 10.1021/CB400400J |
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