Magnesium in PDB 4myo: Crystal Structure of Streptogramin Group A Antibiotic Acetyltransferase Vata From Staphylococcus Aureus

The structure of Crystal Structure of Streptogramin Group A Antibiotic Acetyltransferase Vata From Staphylococcus Aureus, PDB code: 4myo was solved by P.J.Stogios, G.Minasov, A.Dong, E.Evdokimova, V.Yim, M.Krishnamoorthy, R.Dileo, P.Courvalin, A.Savchenko, W.F.Anderson, Center For Structuralgenomics Of Infectious Diseases (Csgid), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	24.67 / 2.70
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	91.836, 184.037, 96.909, 90.00, 90.00, 90.00
R / Rfree (%)	19 / 25.4

The structure of Crystal Structure of Streptogramin Group A Antibiotic Acetyltransferase Vata From Staphylococcus Aureus also contains other interesting chemical elements:

Chlorine

(Cl)

11 atoms

The binding sites of Magnesium atom in the Crystal Structure of Streptogramin Group A Antibiotic Acetyltransferase Vata From Staphylococcus Aureus (pdb code 4myo). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Crystal Structure of Streptogramin Group A Antibiotic Acetyltransferase Vata From Staphylococcus Aureus, PDB code: 4myo:

Magnesium binding site 1 out of 1 in the Crystal Structure of Streptogramin Group A Antibiotic Acetyltransferase Vata From Staphylococcus Aureus


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of Streptogramin Group A Antibiotic Acetyltransferase Vata From Staphylococcus Aureus within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg301 b:58.4 occ:1.00 O A:HOH432 2.1 30.9 1.0 O B:HOH430 2.1 39.5 1.0 O B:HOH429 2.1 21.5 1.0 O A:ASN164 2.2 47.1 1.0 O B:ASN164 2.2 43.5 1.0 O C:ASN164 2.2 44.6 1.0 C B:ASN164 3.1 45.1 1.0 C A:ASN164 3.1 42.8 1.0 C C:ASN164 3.2 36.9 1.0 N B:ASN164 3.8 44.4 1.0 N B:PRO165 3.9 44.1 1.0 N C:PRO165 3.9 41.0 1.0 CD C:PRO165 3.9 30.4 1.0 N A:PRO165 3.9 42.3 1.0 N A:ASN164 3.9 49.8 1.0 CA B:ASN164 4.0 45.3 1.0 N C:ASN164 4.0 41.5 1.0 CD B:PRO165 4.0 38.1 1.0 CD A:PRO165 4.0 31.6 1.0 CA A:ASN164 4.1 41.1 1.0 CA C:ASN164 4.1 37.1 1.0 CB B:ASN164 4.6 44.8 1.0 O B:PRO165 4.6 38.0 1.0 CB A:ASN164 4.7 37.4 1.0 O A:PRO165 4.7 46.0 1.0 O C:PRO165 4.7 45.8 1.0 CB C:ASN164 4.8 37.3 1.0 C B:GLY163 4.9 43.6 1.0

P.J.Stogios, M.L.Kuhn, E.Evdokimova, P.Courvalin, W.F.Anderson, A.Savchenko. Potential For Reduction of Streptogramin A Resistance Revealed By Structural Analysis of the Vata Acetyltransferase. Antimicrob.Agents Chemother. 2014.
ISSN: ESSN 1098-6596
PubMed: 25223995
DOI: 10.1128/AAC.03743-14