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Magnesium in PDB 4nu1: Crystal Structure of A Transition State Mimic of the Gsk-3/Axin Complex Bound to Phosphorylated N-Terminal Auto-Inhibitory PS9 Peptide
Enzymatic activity of Crystal Structure of A Transition State Mimic of the Gsk-3/Axin Complex Bound to Phosphorylated N-Terminal Auto-Inhibitory PS9 Peptide
All present enzymatic activity of Crystal Structure of A Transition State Mimic of the Gsk-3/Axin Complex Bound to Phosphorylated N-Terminal Auto-Inhibitory PS9 Peptide:
2.7.11.1; 2.7.11.26;
2.7.11.1; 2.7.11.26;
Protein crystallography data
The structure of Crystal Structure of A Transition State Mimic of the Gsk-3/Axin Complex Bound to Phosphorylated N-Terminal Auto-Inhibitory PS9 Peptide, PDB code: 4nu1
was solved by
M.L.-H.Chu,
J.L.Stamos,
M.D.Enos,
N.Shah,
W.I.Weis,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 40.50 / 2.50 |
| Space group | P 61 2 2 |
| Cell size a, b, c (Å), α, β, γ (°) | 80.997, 80.997, 280.530, 90.00, 90.00, 120.00 |
| R / Rfree (%) | 19.1 / 24.5 |
Other elements in 4nu1:
The structure of Crystal Structure of A Transition State Mimic of the Gsk-3/Axin Complex Bound to Phosphorylated N-Terminal Auto-Inhibitory PS9 Peptide also contains other interesting chemical elements:
| Fluorine | (F) | 3 atoms |
| Aluminium | (Al) | 1 atom |
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Crystal Structure of A Transition State Mimic of the Gsk-3/Axin Complex Bound to Phosphorylated N-Terminal Auto-Inhibitory PS9 Peptide
(pdb code 4nu1). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Crystal Structure of A Transition State Mimic of the Gsk-3/Axin Complex Bound to Phosphorylated N-Terminal Auto-Inhibitory PS9 Peptide, PDB code: 4nu1:
Jump to Magnesium binding site number: 1; 2;
In total 2 binding sites of Magnesium where determined in the Crystal Structure of A Transition State Mimic of the Gsk-3/Axin Complex Bound to Phosphorylated N-Terminal Auto-Inhibitory PS9 Peptide, PDB code: 4nu1:
Jump to Magnesium binding site number: 1; 2;
Magnesium binding site 1 out of 2 in 4nu1
Go back to
Magnesium Binding Sites List in 4nu1
Magnesium binding site 1 out
of 2 in the Crystal Structure of A Transition State Mimic of the Gsk-3/Axin Complex Bound to Phosphorylated N-Terminal Auto-Inhibitory PS9 Peptide
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Magnesium with other atoms in the Mg binding
site number 1 of Crystal Structure of A Transition State Mimic of the Gsk-3/Axin Complex Bound to Phosphorylated N-Terminal Auto-Inhibitory PS9 Peptide within 5.0Å range:
|
Magnesium binding site 2 out of 2 in 4nu1
Go back to
Magnesium Binding Sites List in 4nu1
Magnesium binding site 2 out
of 2 in the Crystal Structure of A Transition State Mimic of the Gsk-3/Axin Complex Bound to Phosphorylated N-Terminal Auto-Inhibitory PS9 Peptide
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Magnesium with other atoms in the Mg binding
site number 2 of Crystal Structure of A Transition State Mimic of the Gsk-3/Axin Complex Bound to Phosphorylated N-Terminal Auto-Inhibitory PS9 Peptide within 5.0Å range:
|
Reference:
J.L.Stamos,
M.L.Chu,
M.D.Enos,
N.Shah,
W.I.Weis.
Structural Basis of Gsk-3 Inhibition By N-Terminal Phosphorylation and By the Wnt Receptor LRP6. Elife V. 3 01998 2014.
ISSN: ESSN 2050-084X
PubMed: 24642411
Page generated: Mon Aug 19 23:46:43 2024
ISSN: ESSN 2050-084X
PubMed: 24642411
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