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Atomistry » Magnesium » PDB 4nlz-4nxm » 4nw7 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Magnesium » PDB 4nlz-4nxm » 4nw7 » |
Magnesium in PDB 4nw7: PDE4 Catalytic DomainEnzymatic activity of PDE4 Catalytic Domain
All present enzymatic activity of PDE4 Catalytic Domain:
3.1.4.17; Protein crystallography data
The structure of PDE4 Catalytic Domain, PDB code: 4nw7
was solved by
D.Fox Iii,
T.E.Edwards,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4nw7:
The structure of PDE4 Catalytic Domain also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the PDE4 Catalytic Domain
(pdb code 4nw7). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the PDE4 Catalytic Domain, PDB code: 4nw7: Magnesium binding site 1 out of 1 in 4nw7Go back to Magnesium Binding Sites List in 4nw7
Magnesium binding site 1 out
of 1 in the PDE4 Catalytic Domain
Mono view Stereo pair view
Reference:
T.J.Hagen,
X.Mo,
A.B.Burgin,
D.Fox,
Z.Zhang,
M.E.Gurney.
Discovery of Triazines As Selective PDE4B Versus PDE4D Inhibitors. Bioorg.Med.Chem.Lett. V. 24 4031 2014.
Page generated: Mon Dec 14 19:15:35 2020
ISSN: ISSN 0960-894X PubMed: 24998378 DOI: 10.1016/J.BMCL.2014.06.002 |
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