Magnesium in PDB 4oau: Complete Human Rnase L in Complex with Biological Activators.

The structure of Complete Human Rnase L in Complex with Biological Activators., PDB code: 4oau was solved by Y.Han, J.Donovan, S.Rath, G.Whitney, A.Chitrakar, A.Korennykh, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	53.44 / 2.60
Space group	P 21 2 21
Cell size a, b, c (Å), α, β, γ (°)	60.130, 116.600, 162.400, 90.00, 90.00, 90.00
R / Rfree (%)	21.1 / 25.1

The binding sites of Magnesium atom in the Complete Human Rnase L in Complex with Biological Activators. (pdb code 4oau). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Complete Human Rnase L in Complex with Biological Activators., PDB code: 4oau:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Complete Human Rnase L in Complex with Biological Activators.


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Complete Human Rnase L in Complex with Biological Activators. within 5.0Å range: probe atom residue distance (Å) B Occ C:Mg802 b:61.6 occ:1.00 O1B C:ADP801 2.1 66.6 1.0 OD1 C:ASN490 2.1 65.4 1.0 OD2 C:ASP503 2.2 63.8 1.0 O C:HOH923 2.2 45.8 1.0 O2A C:ADP801 2.5 59.9 1.0 CG C:ASN490 2.9 64.9 1.0 ND2 C:ASN490 3.0 63.9 1.0 CG C:ASP503 3.3 64.8 1.0 NE2 C:GLN487 3.4 0.7 1.0 PB C:ADP801 3.4 69.3 1.0 MG C:MG803 3.7 70.0 1.0 OD2 C:ASP485 3.8 77.3 1.0 PA C:ADP801 3.8 62.6 1.0 CB C:ASP503 3.9 64.2 1.0 O3B C:ADP801 3.9 81.8 1.0 O3A C:ADP801 4.1 61.8 1.0 OD1 C:ASP503 4.3 71.0 1.0 CB C:ASN490 4.4 66.4 1.0 CD C:GLN487 4.5 0.4 1.0 O2B C:ADP801 4.6 68.8 1.0 C5' C:ADP801 4.8 61.4 1.0 O1A C:ADP801 4.8 63.9 1.0 O5' C:ADP801 4.8 62.9 1.0 CG C:ASP485 4.8 80.4 1.0 CA C:ASN490 4.9 70.3 1.0

Magnesium binding site 2 out of 2 in the Complete Human Rnase L in Complex with Biological Activators.


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Complete Human Rnase L in Complex with Biological Activators. within 5.0Å range: probe atom residue distance (Å) B Occ C:Mg803 b:70.0 occ:1.00 O3B C:ADP801 2.1 81.8 1.0 OD2 C:ASP503 2.3 63.8 1.0 OD1 C:ASP505 2.3 80.0 1.0 OD1 C:ASP503 2.5 71.0 1.0 CG C:ASP503 2.7 64.8 1.0 PB C:ADP801 3.2 69.3 1.0 O1B C:ADP801 3.3 66.6 1.0 CG C:ASP505 3.3 80.6 1.0 OD2 C:ASP505 3.6 85.2 1.0 MG C:MG802 3.7 61.6 1.0 OD2 C:ASP485 3.7 77.3 1.0 O2B C:ADP801 4.2 68.8 1.0 CB C:ASP503 4.2 64.2 1.0 NH1 C:ARG400 4.3 77.3 1.0 CG C:LYS506 4.3 95.0 1.0 O3A C:ADP801 4.3 61.8 1.0 CD C:LYS506 4.4 0.8 1.0 NZ C:LYS392 4.5 60.9 1.0 O C:HOH949 4.5 57.3 1.0 O2A C:ADP801 4.6 59.9 1.0 CE C:LYS506 4.6 0.1 1.0 CB C:ASP505 4.7 75.2 1.0 N C:ASP505 4.7 66.2 1.0 ND2 C:ASN490 4.7 63.9 1.0 CG C:ASP485 4.8 80.4 1.0 N C:LYS506 4.9 76.8 1.0 PA C:ADP801 4.9 62.6 1.0 CB C:LYS506 4.9 85.9 1.0 CA C:ASP505 5.0 73.9 1.0 C C:ASP505 5.0 79.9 1.0 C C:ASP503 5.0 66.8 1.0

Y.Han, J.Donovan, S.Rath, G.Whitney, A.Chitrakar, A.Korennykh. Structure of Human Rnase L Reveals the Basis For Regulated Rna Decay in the Ifn Response. Science V. 343 1244 2014.
ISSN: ISSN 0036-8075
PubMed: 24578532
DOI: 10.1126/SCIENCE.1249845