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Atomistry » Magnesium » PDB 4o5k-4ogq » 4ocz » |
Magnesium in PDB 4ocz: Crystal Structure of Human Soluble Epoxide Hydrolase Complexed with 1- (1-Isobutyrylpiperidin-4-Yl)-3-(4-(Trifluoromethyl)Phenyl)UreaEnzymatic activity of Crystal Structure of Human Soluble Epoxide Hydrolase Complexed with 1- (1-Isobutyrylpiperidin-4-Yl)-3-(4-(Trifluoromethyl)Phenyl)Urea
All present enzymatic activity of Crystal Structure of Human Soluble Epoxide Hydrolase Complexed with 1- (1-Isobutyrylpiperidin-4-Yl)-3-(4-(Trifluoromethyl)Phenyl)Urea:
3.1.3.76; 3.3.2.10; Protein crystallography data
The structure of Crystal Structure of Human Soluble Epoxide Hydrolase Complexed with 1- (1-Isobutyrylpiperidin-4-Yl)-3-(4-(Trifluoromethyl)Phenyl)Urea, PDB code: 4ocz
was solved by
K.S.S.Lee,
J.Liu,
K.M.Wagner,
S.Pakhomova,
H.Dong,
C.Morriseau,
S.H.Fu,
J.Yang,
P.Wang,
A.Ulu,
C.Mate,
L.Nguyen,
H.Wullf,
M.L.Eldin,
A.A.Mara,
M.E.Newcomer,
D.C.Zeldin,
B.D.Hammock,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4ocz:
The structure of Crystal Structure of Human Soluble Epoxide Hydrolase Complexed with 1- (1-Isobutyrylpiperidin-4-Yl)-3-(4-(Trifluoromethyl)Phenyl)Urea also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Crystal Structure of Human Soluble Epoxide Hydrolase Complexed with 1- (1-Isobutyrylpiperidin-4-Yl)-3-(4-(Trifluoromethyl)Phenyl)Urea
(pdb code 4ocz). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Crystal Structure of Human Soluble Epoxide Hydrolase Complexed with 1- (1-Isobutyrylpiperidin-4-Yl)-3-(4-(Trifluoromethyl)Phenyl)Urea, PDB code: 4ocz: Magnesium binding site 1 out of 1 in 4oczGo back to Magnesium Binding Sites List in 4ocz
Magnesium binding site 1 out
of 1 in the Crystal Structure of Human Soluble Epoxide Hydrolase Complexed with 1- (1-Isobutyrylpiperidin-4-Yl)-3-(4-(Trifluoromethyl)Phenyl)Urea
Mono view Stereo pair view
Reference:
K.S.Lee,
J.Y.Liu,
K.M.Wagner,
S.Pakhomova,
H.Dong,
C.Morisseau,
S.H.Fu,
J.Yang,
P.Wang,
A.Ulu,
C.A.Mate,
L.V.Nguyen,
S.H.Hwang,
M.L.Edin,
A.A.Mara,
H.Wulff,
M.E.Newcomer,
D.C.Zeldin,
B.D.Hammock.
Optimized Inhibitors of Soluble Epoxide Hydrolase Improve in Vitro Target Residence Time and in Vivo Efficacy. J.Med.Chem. V. 57 7016 2014.
Page generated: Mon Dec 14 19:17:21 2020
ISSN: ISSN 0022-2623 PubMed: 25079952 DOI: 10.1021/JM500694P |
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