Magnesium in PDB 4q8h: Structure of the Saccharomyces Cerevisiae PAN2 Pseudoubiquitin- Hydrolase-Rnase Module

All present enzymatic activity of Structure of the Saccharomyces Cerevisiae PAN2 Pseudoubiquitin- Hydrolase-Rnase Module:
3.1.13.4;

The structure of Structure of the Saccharomyces Cerevisiae PAN2 Pseudoubiquitin- Hydrolase-Rnase Module, PDB code: 4q8h was solved by I.B.Schaefer, E.Conti, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.01 / 3.10
Space group	I 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	91.712, 115.505, 257.449, 90.00, 90.00, 90.00
R / Rfree (%)	23.9 / 27.5

The binding sites of Magnesium atom in the Structure of the Saccharomyces Cerevisiae PAN2 Pseudoubiquitin- Hydrolase-Rnase Module (pdb code 4q8h). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Structure of the Saccharomyces Cerevisiae PAN2 Pseudoubiquitin- Hydrolase-Rnase Module, PDB code: 4q8h:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Structure of the Saccharomyces Cerevisiae PAN2 Pseudoubiquitin- Hydrolase-Rnase Module


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Structure of the Saccharomyces Cerevisiae PAN2 Pseudoubiquitin- Hydrolase-Rnase Module within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1201 b:0.7 occ:1.00 MG A:MG1202 1.3 0.4 1.0 OD1 A:ASP910 2.1 0.1 1.0 OE2 A:GLU912 2.1 0.6 1.0 OD2 A:ASP910 2.2 0.2 1.0 CG A:ASP910 2.4 1.0 1.0 OD2 A:ASP1071 2.9 0.1 1.0 CD A:GLU912 3.2 0.5 1.0 CG A:ASP1071 3.7 0.8 1.0 CB A:ASP1071 3.7 1.0 1.0 CB A:ASP910 3.9 0.1 1.0 OE1 A:GLU912 3.9 0.8 1.0 CE1 A:HIS1066 4.0 0.4 1.0 O A:ALA911 4.2 0.4 1.0 CG A:GLU912 4.3 0.1 1.0 NE2 A:HIS1066 4.4 0.6 1.0 N A:ALA911 4.7 0.6 1.0 CA A:ASP910 4.8 0.8 1.0 OD1 A:ASP1071 4.8 0.4 1.0 C A:ALA911 4.8 0.4 1.0 C A:ASP910 4.9 0.2 1.0

Magnesium binding site 2 out of 2 in the Structure of the Saccharomyces Cerevisiae PAN2 Pseudoubiquitin- Hydrolase-Rnase Module


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Structure of the Saccharomyces Cerevisiae PAN2 Pseudoubiquitin- Hydrolase-Rnase Module within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1202 b:0.4 occ:1.00 MG A:MG1201 1.3 0.7 1.0 OE2 A:GLU912 2.0 0.6 1.0 OD2 A:ASP910 2.1 0.2 1.0 OD2 A:ASP1071 2.4 0.1 1.0 CE1 A:HIS1066 2.8 0.4 1.0 CG A:ASP910 2.9 1.0 1.0 CD A:GLU912 2.9 0.5 1.0 OD1 A:ASP910 3.0 0.1 1.0 CG A:ASP1071 3.1 0.8 1.0 NE2 A:HIS1066 3.4 0.6 1.0 CB A:ASP1071 3.5 1.0 1.0 OE1 A:GLU912 3.6 0.8 1.0 CG A:GLU912 3.7 0.1 1.0 OD1 A:ASP1071 4.0 0.4 1.0 ND1 A:HIS1066 4.0 0.7 1.0 CB A:ASP910 4.3 0.1 1.0 CA A:SER1068 4.3 0.1 1.0 O A:ASP1067 4.4 0.4 1.0 CD2 A:HIS1066 4.7 0.2 1.0 O A:ALA911 4.7 0.4 1.0 OG A:SER1068 4.8 0.9 1.0 CB A:SER1068 4.8 0.6 1.0 N A:SER1068 5.0 0.6 1.0 C A:ASP1067 5.0 0.6 1.0 O A:SER1068 5.0 0.2 1.0 CA A:ASP1071 5.0 0.1 1.0

I.B.Schafer, M.Rode, F.Bonneau, S.Schussler, E.Conti. The Structure of the PAN2-PAN3 Core Complex Reveals Cross-Talk Between Deadenylase and Pseudokinase. Nat.Struct.Mol.Biol. V. 21 591 2014.
ISSN: ISSN 1545-9993
PubMed: 24880344
DOI: 10.1038/NSMB.2834