Magnesium in PDB 4qli: A Novel Phospho-Switch in the Linker Region of the Snail Zinc Finger Protein Which Regulates 14-3-3 Association, Dna Binding and Epithelial-Mesenchymal Differentiation

The structure of A Novel Phospho-Switch in the Linker Region of the Snail Zinc Finger Protein Which Regulates 14-3-3 Association, Dna Binding and Epithelial-Mesenchymal Differentiation, PDB code: 4qli was solved by D.Bier, C.Ottmann, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	45.44 / 1.45
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	82.300, 111.900, 62.400, 90.00, 90.00, 90.00
R / Rfree (%)	16.9 / 20.3

The binding sites of Magnesium atom in the A Novel Phospho-Switch in the Linker Region of the Snail Zinc Finger Protein Which Regulates 14-3-3 Association, Dna Binding and Epithelial-Mesenchymal Differentiation (pdb code 4qli). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the A Novel Phospho-Switch in the Linker Region of the Snail Zinc Finger Protein Which Regulates 14-3-3 Association, Dna Binding and Epithelial-Mesenchymal Differentiation, PDB code: 4qli:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the A Novel Phospho-Switch in the Linker Region of the Snail Zinc Finger Protein Which Regulates 14-3-3 Association, Dna Binding and Epithelial-Mesenchymal Differentiation


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of A Novel Phospho-Switch in the Linker Region of the Snail Zinc Finger Protein Which Regulates 14-3-3 Association, Dna Binding and Epithelial-Mesenchymal Differentiation within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg301 b:13.2 occ:0.50 OE1 A:GLU2 2.3 18.6 1.0 O A:HOH555 2.4 34.5 1.0 O A:HOH483 2.4 31.6 1.0 O A:HOH408 2.5 18.3 1.0 CD A:GLU2 3.3 17.9 1.0 OE2 A:GLU2 3.7 16.4 1.0 O A:HOH413 4.2 17.3 1.0 CG A:GLU2 4.5 13.1 1.0 CA A:GLU2 4.8 11.0 1.0 O A:HOH456 4.8 24.5 1.0 CB A:GLU2 4.9 12.7 1.0 N A:ARG3 4.9 11.7 1.0

Magnesium binding site 2 out of 2 in the A Novel Phospho-Switch in the Linker Region of the Snail Zinc Finger Protein Which Regulates 14-3-3 Association, Dna Binding and Epithelial-Mesenchymal Differentiation


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of A Novel Phospho-Switch in the Linker Region of the Snail Zinc Finger Protein Which Regulates 14-3-3 Association, Dna Binding and Epithelial-Mesenchymal Differentiation within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg302 b:15.8 occ:1.00 O A:HOH556 2.4 26.3 1.0 OE2 A:GLU35 2.4 28.0 1.0 O A:HOH557 2.4 31.4 1.0 O A:GLU110 2.5 17.6 1.0 O A:HOH558 2.5 36.9 1.0 OE1 A:GLU35 2.8 35.5 1.0 CD A:GLU35 2.9 28.9 1.0 C A:GLU110 3.6 16.5 1.0 N A:GLY112 4.0 19.1 1.0 CG A:GLU35 4.4 18.8 1.0 CA A:GLU110 4.4 15.2 1.0 O A:HOH477 4.5 29.0 1.0 OE1 A:GLU110 4.5 25.6 0.7 CA A:ALA111 4.5 15.5 1.0 N A:ALA111 4.5 14.5 1.0 O A:HOH577 4.6 39.5 1.0 O A:HOH570 4.6 36.5 1.0 C A:ALA111 4.7 17.1 1.0 CB A:GLU110 4.7 15.3 1.0 CA A:GLY112 4.8 20.0 1.0

Y.Liu, J.W.Prokop, H.Peng, J.Karar, D.White, Z.Hou, Y.S.Qin, D.Bier, C.Ottmann, S.Waxman, T.D.Halazonetis, F.J.Rauscher Iii. A Novel Phospho-Switch in the Linker Region of the Snail Zinc Finger Protein Which Regulates 14-3-3 Association, Dna Binding and Epithelial-Mesenchymal Differentiation To Be Published.