Magnesium in PDB 4roe: Human Tfiib-Related Factor 2 (BRF2) and Tbp Bound to RPPH1 Promoter

The structure of Human Tfiib-Related Factor 2 (BRF2) and Tbp Bound to RPPH1 Promoter, PDB code: 4roe was solved by A.Vannini, J.Gouge, K.Satia, N.Guthertz, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.68 / 2.20
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	77.741, 91.926, 102.423, 90.00, 90.00, 90.00
R / Rfree (%)	19.2 / 22.2

The binding sites of Magnesium atom in the Human Tfiib-Related Factor 2 (BRF2) and Tbp Bound to RPPH1 Promoter (pdb code 4roe). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Human Tfiib-Related Factor 2 (BRF2) and Tbp Bound to RPPH1 Promoter, PDB code: 4roe:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Human Tfiib-Related Factor 2 (BRF2) and Tbp Bound to RPPH1 Promoter


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Human Tfiib-Related Factor 2 (BRF2) and Tbp Bound to RPPH1 Promoter within 5.0Å range: probe atom residue distance (Å) B Occ N:Mg101 b:63.2 occ:1.00 O N:HOH220 2.2 60.2 1.0 O N:HOH221 2.2 56.3 1.0 N7 N:DA18 2.6 48.2 1.0 O N:HOH205 2.6 50.8 1.0 C8 N:DA18 3.5 48.9 1.0 C5 N:DA18 3.6 47.6 1.0 N6 N:DA18 3.7 47.6 1.0 O N:HOH233 4.0 58.0 1.0 C6 N:DA18 4.1 47.9 1.0 N7 N:DG19 4.1 53.3 1.0 N7 N:DA17 4.2 48.4 1.0 O6 N:DG19 4.2 52.4 1.0 C8 N:DA17 4.4 48.4 1.0 N9 N:DA18 4.7 49.4 1.0 C4 N:DA18 4.8 48.4 1.0 C5 N:DG19 4.9 53.4 1.0 C6 N:DG19 4.9 52.4 1.0 OP1 N:DA18 4.9 52.3 1.0

Magnesium binding site 2 out of 2 in the Human Tfiib-Related Factor 2 (BRF2) and Tbp Bound to RPPH1 Promoter


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Human Tfiib-Related Factor 2 (BRF2) and Tbp Bound to RPPH1 Promoter within 5.0Å range: probe atom residue distance (Å) B Occ T:Mg101 b:62.3 occ:1.00 O T:HOH228 2.3 72.0 1.0 O T:HOH227 2.4 67.9 1.0 O T:HOH234 2.5 67.4 1.0 O T:HOH222 2.6 59.3 1.0 N7 T:DA17 2.7 45.4 1.0 C8 T:DA17 3.6 45.5 1.0 C5 T:DA17 3.7 45.4 1.0 N6 T:DA17 3.7 44.5 1.0 O6 T:DG18 4.0 45.8 1.0 C6 T:DA17 4.1 45.0 1.0 N7 T:DA16 4.2 43.2 1.0 C8 T:DA16 4.5 44.5 1.0 O T:HOH210 4.5 75.1 1.0 N7 T:DG18 4.6 45.3 1.0 O T:HOH229 4.8 59.2 1.0 N9 T:DA17 4.8 46.7 1.0 C4 T:DA17 4.9 46.2 1.0 C6 T:DG18 4.9 45.1 1.0

J.Gouge, K.Satia, N.Guthertz, M.Widya, A.J.Thompson, P.Cousin, O.Dergai, N.Hernandez, A.Vannini. Redox Signaling By the Rna Polymerase III Tfiib-Related Factor BRF2. Cell(Cambridge,Mass.) V. 163 1375 2015.
ISSN: ISSN 0092-8674
PubMed: 26638071
DOI: 10.1016/J.CELL.2015.11.005