Magnesium in PDB 4xeo: Crystal Structure of Human Alars Catalytic Domain with R329H Mutation

All present enzymatic activity of Crystal Structure of Human Alars Catalytic Domain with R329H Mutation:
6.1.1.7;

The structure of Crystal Structure of Human Alars Catalytic Domain with R329H Mutation, PDB code: 4xeo was solved by H.Zhou, W.He, X.L.Yang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	33.96 / 1.38
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	64.848, 121.172, 68.012, 90.00, 118.47, 90.00
R / Rfree (%)	18.3 / 21.4

The binding sites of Magnesium atom in the Crystal Structure of Human Alars Catalytic Domain with R329H Mutation (pdb code 4xeo). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Crystal Structure of Human Alars Catalytic Domain with R329H Mutation, PDB code: 4xeo:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Crystal Structure of Human Alars Catalytic Domain with R329H Mutation


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of Human Alars Catalytic Domain with R329H Mutation within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg506 b:18.0 occ:1.00 O A:HOH863 1.9 30.3 1.0 OE2 A:GLU213 2.0 21.5 1.0 OE2 A:GLU189 2.0 17.7 1.0 O A:HOH784 2.0 25.6 1.0 O A:HOH1016 2.0 32.0 1.0 O A:HOH820 2.1 34.6 1.0 CD A:GLU213 3.0 16.6 1.0 CD A:GLU189 3.1 16.3 1.0 OE1 A:GLU213 3.4 17.1 1.0 CG A:GLU189 3.8 16.2 1.0 O A:HOH849 4.1 28.6 1.0 OE1 A:GLU189 4.1 18.5 1.0 O A:ASP173 4.2 19.9 1.0 OD1 A:ASN205 4.2 24.7 1.0 CG A:GLU213 4.3 13.7 1.0 ND2 A:ASN205 4.7 22.9 1.0 O2S A:A5A501 4.7 12.2 1.0 CB A:GLU213 4.7 12.3 1.0 CB A:GLU189 4.8 14.0 1.0 CG A:ASN205 4.9 21.7 1.0

Magnesium binding site 2 out of 2 in the Crystal Structure of Human Alars Catalytic Domain with R329H Mutation


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Crystal Structure of Human Alars Catalytic Domain with R329H Mutation within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg506 b:19.3 occ:1.00 O B:HOH771 1.9 29.6 1.0 OE2 B:GLU213 2.0 22.0 1.0 OE2 B:GLU189 2.0 19.4 1.0 O B:HOH714 2.0 22.7 1.0 O B:HOH977 2.1 31.3 1.0 O B:HOH976 2.1 42.3 1.0 CD B:GLU213 3.0 16.9 1.0 CD B:GLU189 3.1 18.2 1.0 OE1 B:GLU213 3.4 18.1 1.0 CG B:GLU189 3.7 17.9 1.0 OE1 B:GLU189 4.1 19.1 1.0 O B:HOH826 4.2 31.3 1.0 O B:ASP173 4.2 21.3 1.0 ND2 B:ASN205 4.2 23.2 1.0 CG B:GLU213 4.3 15.3 1.0 O B:HOH843 4.4 32.2 1.0 OD1 B:ASN205 4.7 26.0 1.0 CB B:GLU213 4.7 14.5 1.0 CB B:GLU189 4.8 15.9 1.0 O2S B:A5A501 4.8 13.9 1.0 CG B:ASN205 4.9 24.5 1.0

X.L.Yang, H.Zhou, W.He, X.L.Yang. N/A N/A.