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Atomistry » Magnesium » PDB 4xtj-4y2p » 4xuc » |
Magnesium in PDB 4xuc: Synthesis and Evaluation of Heterocyclic Catechol Mimics As Inhibitors of Catechol-O-Methyltransferase (Comt): Structure with CMPD18 (1- (Biphenyl-3-Yl)-3-Hydroxypyridin-4(1H)-One)Enzymatic activity of Synthesis and Evaluation of Heterocyclic Catechol Mimics As Inhibitors of Catechol-O-Methyltransferase (Comt): Structure with CMPD18 (1- (Biphenyl-3-Yl)-3-Hydroxypyridin-4(1H)-One)
All present enzymatic activity of Synthesis and Evaluation of Heterocyclic Catechol Mimics As Inhibitors of Catechol-O-Methyltransferase (Comt): Structure with CMPD18 (1- (Biphenyl-3-Yl)-3-Hydroxypyridin-4(1H)-One):
2.1.1.6; Protein crystallography data
The structure of Synthesis and Evaluation of Heterocyclic Catechol Mimics As Inhibitors of Catechol-O-Methyltransferase (Comt): Structure with CMPD18 (1- (Biphenyl-3-Yl)-3-Hydroxypyridin-4(1H)-One), PDB code: 4xuc
was solved by
T.Allison,
S.Wolkenberg,
J.M.Sanders,
S.M.Soisson,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Synthesis and Evaluation of Heterocyclic Catechol Mimics As Inhibitors of Catechol-O-Methyltransferase (Comt): Structure with CMPD18 (1- (Biphenyl-3-Yl)-3-Hydroxypyridin-4(1H)-One)
(pdb code 4xuc). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Synthesis and Evaluation of Heterocyclic Catechol Mimics As Inhibitors of Catechol-O-Methyltransferase (Comt): Structure with CMPD18 (1- (Biphenyl-3-Yl)-3-Hydroxypyridin-4(1H)-One), PDB code: 4xuc: Magnesium binding site 1 out of 1 in 4xucGo back to Magnesium Binding Sites List in 4xuc
Magnesium binding site 1 out
of 1 in the Synthesis and Evaluation of Heterocyclic Catechol Mimics As Inhibitors of Catechol-O-Methyltransferase (Comt): Structure with CMPD18 (1- (Biphenyl-3-Yl)-3-Hydroxypyridin-4(1H)-One)
Mono view Stereo pair view
Reference:
S.T.Harrison,
M.S.Poslusney,
J.J.Mulhearn,
Z.Zhao,
N.R.Kett,
J.W.Schubert,
J.Y.Melamed,
T.J.Allison,
S.B.Patel,
J.M.Sanders,
S.Sharma,
R.F.Smith,
D.L.Hall,
R.G.Robinson,
N.A.Sachs,
P.H.Hutson,
S.E.Wolkenberg,
J.C.Barrow.
Synthesis and Evaluation of Heterocyclic Catechol Mimics As Inhibitors of Catechol-O-Methyltransferase (Comt). Acs Med.Chem.Lett. V. 6 318 2015.
Page generated: Mon Dec 14 19:48:24 2020
ISSN: ISSN 1948-5875 PubMed: 25815153 DOI: 10.1021/ML500502D |
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