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Atomistry » Magnesium » PDB 4xtj-4y2p » 4xy2 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Magnesium » PDB 4xtj-4y2p » 4xy2 » |
Magnesium in PDB 4xy2: Crystal Structure of PDE10A in Complex with ASP9436Enzymatic activity of Crystal Structure of PDE10A in Complex with ASP9436
All present enzymatic activity of Crystal Structure of PDE10A in Complex with ASP9436:
3.1.4.17; 3.1.4.35; Protein crystallography data
The structure of Crystal Structure of PDE10A in Complex with ASP9436, PDB code: 4xy2
was solved by
Y.Amano,
K.Honbou,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4xy2:
The structure of Crystal Structure of PDE10A in Complex with ASP9436 also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Crystal Structure of PDE10A in Complex with ASP9436
(pdb code 4xy2). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Crystal Structure of PDE10A in Complex with ASP9436, PDB code: 4xy2: Jump to Magnesium binding site number: 1; 2; Magnesium binding site 1 out of 2 in 4xy2Go back to Magnesium Binding Sites List in 4xy2
Magnesium binding site 1 out
of 2 in the Crystal Structure of PDE10A in Complex with ASP9436
Mono view Stereo pair view
Magnesium binding site 2 out of 2 in 4xy2Go back to Magnesium Binding Sites List in 4xy2
Magnesium binding site 2 out
of 2 in the Crystal Structure of PDE10A in Complex with ASP9436
Mono view Stereo pair view
Reference:
W.Hamaguchi,
N.Masuda,
S.Miyamoto,
S.Kikuchi,
F.Narazaki,
Y.Shiina,
R.Seo,
Y.Amano,
T.Mihara,
H.Moriguchi,
K.Hattori.
Addressing Phototoxicity Observed in A Novel Series of Biaryl Derivatives: Discovery of Potent, Selective and Orally Active Phosphodiesterase 10A Inhibitor ASP9436 Bioorg.Med.Chem. V. 23 3351 2015.
Page generated: Tue Aug 20 16:03:13 2024
ISSN: ESSN 1464-3391 PubMed: 25960322 DOI: 10.1016/J.BMC.2015.04.052 |
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