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Magnesium in PDB 4yd1: Ternary Complex of Human Dna Polymerase Mu with 2-Nt Gapped Dna Substrate and An Incoming Nonhydrolyzable Dumpnpp
Enzymatic activity of Ternary Complex of Human Dna Polymerase Mu with 2-Nt Gapped Dna Substrate and An Incoming Nonhydrolyzable Dumpnpp
All present enzymatic activity of Ternary Complex of Human Dna Polymerase Mu with 2-Nt Gapped Dna Substrate and An Incoming Nonhydrolyzable Dumpnpp:
2.7.7.7;
2.7.7.7;
Protein crystallography data
The structure of Ternary Complex of Human Dna Polymerase Mu with 2-Nt Gapped Dna Substrate and An Incoming Nonhydrolyzable Dumpnpp, PDB code: 4yd1
was solved by
A.F.Moon,
R.A.Gosavi,
T.A.Kunkel,
L.C.Pedersen,
K.Bebenek,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 24.97 / 1.75 |
| Space group | P 21 21 21 |
| Cell size a, b, c (Å), α, β, γ (°) | 60.259, 69.042, 116.988, 90.00, 90.00, 90.00 |
| R / Rfree (%) | 16.3 / 19 |
Other elements in 4yd1:
The structure of Ternary Complex of Human Dna Polymerase Mu with 2-Nt Gapped Dna Substrate and An Incoming Nonhydrolyzable Dumpnpp also contains other interesting chemical elements:
| Chlorine | (Cl) | 4 atoms |
| Sodium | (Na) | 1 atom |
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Ternary Complex of Human Dna Polymerase Mu with 2-Nt Gapped Dna Substrate and An Incoming Nonhydrolyzable Dumpnpp
(pdb code 4yd1). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 3 binding sites of Magnesium where determined in the Ternary Complex of Human Dna Polymerase Mu with 2-Nt Gapped Dna Substrate and An Incoming Nonhydrolyzable Dumpnpp, PDB code: 4yd1:
Jump to Magnesium binding site number: 1; 2; 3;
In total 3 binding sites of Magnesium where determined in the Ternary Complex of Human Dna Polymerase Mu with 2-Nt Gapped Dna Substrate and An Incoming Nonhydrolyzable Dumpnpp, PDB code: 4yd1:
Jump to Magnesium binding site number: 1; 2; 3;
Magnesium binding site 1 out of 3 in 4yd1
Go back to
Magnesium Binding Sites List in 4yd1
Magnesium binding site 1 out
of 3 in the Ternary Complex of Human Dna Polymerase Mu with 2-Nt Gapped Dna Substrate and An Incoming Nonhydrolyzable Dumpnpp
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Magnesium with other atoms in the Mg binding
site number 1 of Ternary Complex of Human Dna Polymerase Mu with 2-Nt Gapped Dna Substrate and An Incoming Nonhydrolyzable Dumpnpp within 5.0Å range:
|
Magnesium binding site 2 out of 3 in 4yd1
Go back to
Magnesium Binding Sites List in 4yd1
Magnesium binding site 2 out
of 3 in the Ternary Complex of Human Dna Polymerase Mu with 2-Nt Gapped Dna Substrate and An Incoming Nonhydrolyzable Dumpnpp
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Magnesium with other atoms in the Mg binding
site number 2 of Ternary Complex of Human Dna Polymerase Mu with 2-Nt Gapped Dna Substrate and An Incoming Nonhydrolyzable Dumpnpp within 5.0Å range:
|
Magnesium binding site 3 out of 3 in 4yd1
Go back to
Magnesium Binding Sites List in 4yd1
Magnesium binding site 3 out
of 3 in the Ternary Complex of Human Dna Polymerase Mu with 2-Nt Gapped Dna Substrate and An Incoming Nonhydrolyzable Dumpnpp
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Magnesium with other atoms in the Mg binding
site number 3 of Ternary Complex of Human Dna Polymerase Mu with 2-Nt Gapped Dna Substrate and An Incoming Nonhydrolyzable Dumpnpp within 5.0Å range:
|
Reference:
A.F.Moon,
R.A.Gosavi,
T.A.Kunkel,
L.C.Pedersen,
K.Bebenek.
Creative Template-Dependent Synthesis By Human Polymerase Mu. Proc.Natl.Acad.Sci.Usa V. 112 E4530 2015.
ISSN: ESSN 1091-6490
PubMed: 26240373
DOI: 10.1073/PNAS.1505798112
Page generated: Sat Sep 28 23:14:11 2024
ISSN: ESSN 1091-6490
PubMed: 26240373
DOI: 10.1073/PNAS.1505798112
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