Magnesium in PDB 4ydh: The Structure of Human FMNL1 N-Terminal Domains Bound to CDC42

The structure of The Structure of Human FMNL1 N-Terminal Domains Bound to CDC42, PDB code: 4ydh was solved by S.Kuhn, K.Anand, M.Geyer, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.70 / 3.80
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	87.600, 102.100, 170.600, 90.00, 90.00, 90.00
R / Rfree (%)	20.8 / 28.1

The binding sites of Magnesium atom in the The Structure of Human FMNL1 N-Terminal Domains Bound to CDC42 (pdb code 4ydh). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the The Structure of Human FMNL1 N-Terminal Domains Bound to CDC42, PDB code: 4ydh:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the The Structure of Human FMNL1 N-Terminal Domains Bound to CDC42


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of The Structure of Human FMNL1 N-Terminal Domains Bound to CDC42 within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg202 b:73.2 occ:1.00 OG1 B:THR17 2.0 84.0 1.0 O2G B:GNP201 2.1 9.2 1.0 OG1 B:THR35 2.1 95.9 1.0 O2B B:GNP201 2.3 8.4 1.0 CG2 B:THR35 2.8 0.8 1.0 CB B:THR35 3.0 0.8 1.0 PG B:GNP201 3.2 10.6 1.0 OD2 B:ASP57 3.3 97.8 1.0 CB B:THR17 3.4 86.2 1.0 PB B:GNP201 3.4 8.2 1.0 N B:THR35 3.6 0.9 1.0 O3G B:GNP201 3.7 11.5 1.0 N3B B:GNP201 3.7 8.8 1.0 CA B:THR35 3.9 0.9 1.0 CG2 B:THR17 4.1 86.0 1.0 CG B:ASP57 4.1 87.7 1.0 O B:VAL33 4.1 0.4 1.0 OD1 B:ASP57 4.1 80.0 1.0 N B:THR17 4.3 85.5 1.0 O1B B:GNP201 4.3 7.9 1.0 CA B:THR17 4.4 83.0 1.0 O B:THR58 4.4 94.9 1.0 O1G B:GNP201 4.5 12.4 1.0 O3A B:GNP201 4.7 8.8 1.0 O B:THR35 4.7 94.7 1.0 C B:THR35 4.8 0.9 1.0 O1A B:GNP201 4.8 10.3 1.0 C B:PRO34 4.8 0.0 1.0 CE B:LYS16 5.0 82.3 1.0

Magnesium binding site 2 out of 2 in the The Structure of Human FMNL1 N-Terminal Domains Bound to CDC42


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of The Structure of Human FMNL1 N-Terminal Domains Bound to CDC42 within 5.0Å range: probe atom residue distance (Å) B Occ D:Mg202 b:92.7 occ:1.00 OG1 D:THR35 1.9 1.0 1.0 OG1 D:THR17 2.0 0.2 1.0 OD2 D:ASP57 2.5 0.9 1.0 O1G D:GNP201 2.6 9.2 1.0 O1B D:GNP201 2.7 8.4 1.0 CB D:THR35 2.8 0.7 1.0 CG2 D:THR35 2.8 0.5 1.0 CG D:ASP57 3.2 0.4 1.0 OD1 D:ASP57 3.2 97.0 1.0 CB D:THR17 3.4 99.4 1.0 PG D:GNP201 3.7 10.6 1.0 O D:THR58 3.8 80.0 1.0 N D:THR17 3.9 88.4 1.0 PB D:GNP201 3.9 8.2 1.0 CA D:THR17 4.0 88.4 1.0 CG2 D:THR17 4.0 99.2 1.0 O3G D:GNP201 4.1 11.5 1.0 CA D:THR35 4.1 0.0 1.0 CB D:LYS16 4.3 91.8 1.0 N D:THR35 4.3 0.5 1.0 N3B D:GNP201 4.3 8.8 1.0 CB D:ASP57 4.7 90.4 1.0 O2B D:GNP201 4.7 7.9 1.0 C D:LYS16 4.7 92.8 1.0 O D:THR35 4.8 94.3 1.0 C D:THR35 4.8 98.0 1.0 C D:THR58 4.8 81.6 1.0 CD D:LYS16 5.0 80.4 1.0

S.Kuhn, C.Erdmann, F.Kage, J.Block, L.Schwenkmezger, A.Steffen, K.Rottner, M.Geyer. The Structure of FMNL2-CDC42 Yields Insights Into the Mechanism of Lamellipodia and Filopodia Formation. Nat Commun V. 6 7088 2015.
ISSN: ESSN 2041-1723
PubMed: 25963737
DOI: 10.1038/NCOMMS8088