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Magnesium in PDB 4zdq: Crystal Structure of 2-C-Methyl-D-Erythritol 4-Phosphate Cytidylyltransferase (Ispd) From Burkholderia Thailandensis Complexed with Ctp

Enzymatic activity of Crystal Structure of 2-C-Methyl-D-Erythritol 4-Phosphate Cytidylyltransferase (Ispd) From Burkholderia Thailandensis Complexed with Ctp

All present enzymatic activity of Crystal Structure of 2-C-Methyl-D-Erythritol 4-Phosphate Cytidylyltransferase (Ispd) From Burkholderia Thailandensis Complexed with Ctp:
2.7.7.60;

Protein crystallography data

The structure of Crystal Structure of 2-C-Methyl-D-Erythritol 4-Phosphate Cytidylyltransferase (Ispd) From Burkholderia Thailandensis Complexed with Ctp, PDB code: 4zdq was solved by Seattle Structural Genomics Center For Infectious Disease (Ssgcid), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 26.93 / 2.30
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 45.900, 138.950, 76.920, 90.00, 101.94, 90.00
R / Rfree (%) 20.5 / 25.7

Other elements in 4zdq:

The structure of Crystal Structure of 2-C-Methyl-D-Erythritol 4-Phosphate Cytidylyltransferase (Ispd) From Burkholderia Thailandensis Complexed with Ctp also contains other interesting chemical elements:

Arsenic (As) 1 atom

Magnesium Binding Sites:

The binding sites of Magnesium atom in the Crystal Structure of 2-C-Methyl-D-Erythritol 4-Phosphate Cytidylyltransferase (Ispd) From Burkholderia Thailandensis Complexed with Ctp (pdb code 4zdq). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Crystal Structure of 2-C-Methyl-D-Erythritol 4-Phosphate Cytidylyltransferase (Ispd) From Burkholderia Thailandensis Complexed with Ctp, PDB code: 4zdq:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in 4zdq

Go back to Magnesium Binding Sites List in 4zdq
Magnesium binding site 1 out of 2 in the Crystal Structure of 2-C-Methyl-D-Erythritol 4-Phosphate Cytidylyltransferase (Ispd) From Burkholderia Thailandensis Complexed with Ctp


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of 2-C-Methyl-D-Erythritol 4-Phosphate Cytidylyltransferase (Ispd) From Burkholderia Thailandensis Complexed with Ctp within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mg302

b:32.2
occ:1.00
O A:HOH448 2.3 29.1 1.0
O2A A:CTP301 2.3 43.9 1.0
O2B A:CTP301 2.4 26.3 1.0
O3G A:CTP301 2.4 44.0 1.0
O A:HOH454 2.6 55.7 1.0
PB A:CTP301 3.5 38.3 1.0
PG A:CTP301 3.6 45.8 1.0
PA A:CTP301 3.6 46.3 1.0
O3B A:CTP301 3.9 43.6 1.0
O3A A:CTP301 4.0 50.6 1.0
O2G A:CTP301 4.0 44.5 1.0
NH2 A:ARG17 4.1 35.2 1.0
O5' A:CTP301 4.2 47.6 1.0
O A:HOH449 4.3 40.0 1.0
C6 A:CTP301 4.5 24.5 1.0
C5 A:CTP301 4.6 25.4 1.0
O1B A:CTP301 4.8 35.7 1.0
O1A A:CTP301 4.8 34.4 1.0
O1G A:CTP301 4.8 52.1 1.0
CZ A:ARG17 5.0 44.2 1.0

Magnesium binding site 2 out of 2 in 4zdq

Go back to Magnesium Binding Sites List in 4zdq
Magnesium binding site 2 out of 2 in the Crystal Structure of 2-C-Methyl-D-Erythritol 4-Phosphate Cytidylyltransferase (Ispd) From Burkholderia Thailandensis Complexed with Ctp


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Crystal Structure of 2-C-Methyl-D-Erythritol 4-Phosphate Cytidylyltransferase (Ispd) From Burkholderia Thailandensis Complexed with Ctp within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Mg302

b:57.5
occ:1.00
O2B D:CTP301 2.2 83.8 1.0
O2A D:CTP301 2.4 85.8 1.0
PA D:CTP301 3.5 84.6 1.0
O2G D:CTP301 3.5 91.7 1.0
PB D:CTP301 3.6 85.6 1.0
O5' D:CTP301 3.9 84.8 1.0
O1G D:CTP301 3.9 89.3 1.0
O3A D:CTP301 4.0 86.5 1.0
PG D:CTP301 4.2 91.0 1.0
O D:HOH426 4.2 42.5 1.0
C6 D:CTP301 4.2 79.2 1.0
C5 D:CTP301 4.3 79.5 1.0
O3B D:CTP301 4.3 88.8 1.0
O D:HOH437 4.6 47.0 1.0
O1B D:CTP301 4.7 82.6 1.0
O1A D:CTP301 4.8 81.5 1.0

Reference:

Seattle Structural Genomics Center For Infectious Disease(Ssgcid), D.M.Dranow, J.W.Fairman, P.G.Pierce, D.Lorimer, T.E.Edwards. Crystal Structure of 2-C-Methyl-D-Erythritol 4-Phosphate Cytidylyltransferase (Ispd) From Burkholderia Thailandensis Complexed with Ctp To Be Published.
Page generated: Mon Dec 14 19:56:52 2020

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