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Magnesium in PDB 5aix: Complex of Human Hematopoietic Prostagandin D2 Synthase (Hh- Pgds) in Complex with An Active Site Inhibitor.
Enzymatic activity of Complex of Human Hematopoietic Prostagandin D2 Synthase (Hh- Pgds) in Complex with An Active Site Inhibitor.
All present enzymatic activity of Complex of Human Hematopoietic Prostagandin D2 Synthase (Hh- Pgds) in Complex with An Active Site Inhibitor.:
2.5.1.18; 5.3.99.2;
2.5.1.18; 5.3.99.2;
Protein crystallography data
The structure of Complex of Human Hematopoietic Prostagandin D2 Synthase (Hh- Pgds) in Complex with An Active Site Inhibitor., PDB code: 5aix
was solved by
F.Edfeldt,
J.Evenas,
M.Lepisto,
A.Ward,
J.Petersen,
L.Wissler,
M.Rohman,
U.Sivars,
K.Svensson,
M.Perry,
I.Feierberg,
X.Zhou,
T.Hansson,
F.Narjes,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 38.65 / 2.10 |
| Space group | I 41 |
| Cell size a, b, c (Å), α, β, γ (°) | 122.228, 122.228, 106.023, 90.00, 90.00, 90.00 |
| R / Rfree (%) | 25.63 / 34.295 |
Other elements in 5aix:
The structure of Complex of Human Hematopoietic Prostagandin D2 Synthase (Hh- Pgds) in Complex with An Active Site Inhibitor. also contains other interesting chemical elements:
| Fluorine | (F) | 6 atoms |
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Complex of Human Hematopoietic Prostagandin D2 Synthase (Hh- Pgds) in Complex with An Active Site Inhibitor.
(pdb code 5aix). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Complex of Human Hematopoietic Prostagandin D2 Synthase (Hh- Pgds) in Complex with An Active Site Inhibitor., PDB code: 5aix:
Jump to Magnesium binding site number: 1; 2;
In total 2 binding sites of Magnesium where determined in the Complex of Human Hematopoietic Prostagandin D2 Synthase (Hh- Pgds) in Complex with An Active Site Inhibitor., PDB code: 5aix:
Jump to Magnesium binding site number: 1; 2;
Magnesium binding site 1 out of 2 in 5aix
Go back to
Magnesium Binding Sites List in 5aix
Magnesium binding site 1 out
of 2 in the Complex of Human Hematopoietic Prostagandin D2 Synthase (Hh- Pgds) in Complex with An Active Site Inhibitor.
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Magnesium with other atoms in the Mg binding
site number 1 of Complex of Human Hematopoietic Prostagandin D2 Synthase (Hh- Pgds) in Complex with An Active Site Inhibitor. within 5.0Å range:
|
Magnesium binding site 2 out of 2 in 5aix
Go back to
Magnesium Binding Sites List in 5aix
Magnesium binding site 2 out
of 2 in the Complex of Human Hematopoietic Prostagandin D2 Synthase (Hh- Pgds) in Complex with An Active Site Inhibitor.
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Magnesium with other atoms in the Mg binding
site number 2 of Complex of Human Hematopoietic Prostagandin D2 Synthase (Hh- Pgds) in Complex with An Active Site Inhibitor. within 5.0Å range:
|
Reference:
F.Edfeldt,
J.Even,
M.Lepisto,
A.Ward,
J.Petersen,
L.Wissler,
M.Rohman,
U.Sivars,
K.Svensson,
M.Perry,
I.Feierberg,
X.H.Zhou,
T.Hansson,
F.Narjes.
Identification of Indole Inhibitors of Human Hematopoietic Prostaglandin D2 Synthase (Hh-Pgds). Bioorg.Med.Chem.Lett. V. 25 2496 2015.
ISSN: ISSN 0960-894X
PubMed: 25978964
DOI: 10.1016/J.BMCL.2015.04.065
Page generated: Sun Sep 29 00:32:47 2024
ISSN: ISSN 0960-894X
PubMed: 25978964
DOI: 10.1016/J.BMCL.2015.04.065
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