Magnesium in PDB 5btv: Crystal Structure of Human 14-3-3 Sigma in Complex with A Tau-Protein Peptide Surrounding PS324

The structure of Crystal Structure of Human 14-3-3 Sigma in Complex with A Tau-Protein Peptide Surrounding PS324, PDB code: 5btv was solved by C.Ottmann, B.Schumacher, M.Bartel, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	10.00 / 1.70
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	82.550, 112.310, 62.570, 90.00, 90.00, 90.00
R / Rfree (%)	16 / 20.3

The structure of Crystal Structure of Human 14-3-3 Sigma in Complex with A Tau-Protein Peptide Surrounding PS324 also contains other interesting chemical elements:

Calcium	(Ca)	1 atom
Chlorine	(Cl)	1 atom

The binding sites of Magnesium atom in the Crystal Structure of Human 14-3-3 Sigma in Complex with A Tau-Protein Peptide Surrounding PS324 (pdb code 5btv). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Crystal Structure of Human 14-3-3 Sigma in Complex with A Tau-Protein Peptide Surrounding PS324, PDB code: 5btv:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Crystal Structure of Human 14-3-3 Sigma in Complex with A Tau-Protein Peptide Surrounding PS324


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of Human 14-3-3 Sigma in Complex with A Tau-Protein Peptide Surrounding PS324 within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg301 b:8.6 occ:1.00 O A:HOH549 2.3 24.1 1.0 OE2 A:GLU188 2.4 19.7 1.0 CD A:GLU188 3.4 13.6 1.0 CG A:GLU188 3.9 12.4 1.0 OE1 A:GLU188 4.5 17.2 1.0 O A:HOH695 4.7 28.1 1.0

Magnesium binding site 2 out of 2 in the Crystal Structure of Human 14-3-3 Sigma in Complex with A Tau-Protein Peptide Surrounding PS324


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Crystal Structure of Human 14-3-3 Sigma in Complex with A Tau-Protein Peptide Surrounding PS324 within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg303 b:8.1 occ:0.50 O A:HOH627 2.3 30.9 1.0 OE1 A:GLU2 2.4 15.4 1.0 O A:HOH439 2.5 16.1 1.0 O A:HOH657 2.7 31.1 1.0 CD A:GLU2 3.4 15.7 1.0 OE2 A:GLU2 3.8 15.9 1.0 O A:HOH586 4.3 13.6 1.0 O A:HOH701 4.5 12.6 1.0 CG A:GLU2 4.7 12.2 1.0 CA A:GLU2 4.9 10.4 1.0 N A:ARG3 5.0 8.5 1.0 O A:HOH471 5.0 21.9 1.0

Y.Joo, B.Schumacher, I.Landrieu, M.Bartel, C.Smet-Nocca, A.Jang, H.S.Choi, N.L.Jeon, K.A.Chang, H.S.Kim, C.Ottmann, Y.H.Suh. Involvement of 14-3-3 in Tubulin Instability and Impaired Axon Development Is Mediated By Tau. Faseb J. V. 29 4133 2015.
ISSN: ESSN 1530-6860
PubMed: 26103986
DOI: 10.1096/FJ.14-265009