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Magnesium in PDB 5e41: Crystal Structure of the Large Fragment of Dna Polymerase I From Thermus Aquaticus in A Closed Ternary Complex with 5-(N-(10- Hydroxydecanoyl)-Aminopentenyl)-2'-Deoxyuridine-Triphosphate
Enzymatic activity of Crystal Structure of the Large Fragment of Dna Polymerase I From Thermus Aquaticus in A Closed Ternary Complex with 5-(N-(10- Hydroxydecanoyl)-Aminopentenyl)-2'-Deoxyuridine-Triphosphate
All present enzymatic activity of Crystal Structure of the Large Fragment of Dna Polymerase I From Thermus Aquaticus in A Closed Ternary Complex with 5-(N-(10- Hydroxydecanoyl)-Aminopentenyl)-2'-Deoxyuridine-Triphosphate:
2.7.7.7;
2.7.7.7;
Protein crystallography data
The structure of Crystal Structure of the Large Fragment of Dna Polymerase I From Thermus Aquaticus in A Closed Ternary Complex with 5-(N-(10- Hydroxydecanoyl)-Aminopentenyl)-2'-Deoxyuridine-Triphosphate, PDB code: 5e41
was solved by
A.Hottin,
K.Betz,
A.Marx,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 46.67 / 1.80 |
| Space group | P 31 2 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 107.774, 107.774, 89.614, 90.00, 90.00, 120.00 |
| R / Rfree (%) | 19.2 / 23.6 |
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Crystal Structure of the Large Fragment of Dna Polymerase I From Thermus Aquaticus in A Closed Ternary Complex with 5-(N-(10- Hydroxydecanoyl)-Aminopentenyl)-2'-Deoxyuridine-Triphosphate
(pdb code 5e41). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Crystal Structure of the Large Fragment of Dna Polymerase I From Thermus Aquaticus in A Closed Ternary Complex with 5-(N-(10- Hydroxydecanoyl)-Aminopentenyl)-2'-Deoxyuridine-Triphosphate, PDB code: 5e41:
Jump to Magnesium binding site number: 1; 2;
In total 2 binding sites of Magnesium where determined in the Crystal Structure of the Large Fragment of Dna Polymerase I From Thermus Aquaticus in A Closed Ternary Complex with 5-(N-(10- Hydroxydecanoyl)-Aminopentenyl)-2'-Deoxyuridine-Triphosphate, PDB code: 5e41:
Jump to Magnesium binding site number: 1; 2;
Magnesium binding site 1 out of 2 in 5e41
Go back to
Magnesium Binding Sites List in 5e41
Magnesium binding site 1 out
of 2 in the Crystal Structure of the Large Fragment of Dna Polymerase I From Thermus Aquaticus in A Closed Ternary Complex with 5-(N-(10- Hydroxydecanoyl)-Aminopentenyl)-2'-Deoxyuridine-Triphosphate
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Magnesium with other atoms in the Mg binding
site number 1 of Crystal Structure of the Large Fragment of Dna Polymerase I From Thermus Aquaticus in A Closed Ternary Complex with 5-(N-(10- Hydroxydecanoyl)-Aminopentenyl)-2'-Deoxyuridine-Triphosphate within 5.0Å range:
|
Magnesium binding site 2 out of 2 in 5e41
Go back to
Magnesium Binding Sites List in 5e41
Magnesium binding site 2 out
of 2 in the Crystal Structure of the Large Fragment of Dna Polymerase I From Thermus Aquaticus in A Closed Ternary Complex with 5-(N-(10- Hydroxydecanoyl)-Aminopentenyl)-2'-Deoxyuridine-Triphosphate
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Magnesium with other atoms in the Mg binding
site number 2 of Crystal Structure of the Large Fragment of Dna Polymerase I From Thermus Aquaticus in A Closed Ternary Complex with 5-(N-(10- Hydroxydecanoyl)-Aminopentenyl)-2'-Deoxyuridine-Triphosphate within 5.0Å range:
|
Reference:
A.Hottin,
K.Betz,
K.Diederichs,
A.Marx.
Structural Basis For the Klentaq Dna Polymerase Catalysed Incorporation of Alkene- Versus Alkyne-Modified Nucleotides. Chemistry V. 23 2109 2017.
ISSN: ISSN 1521-3765
PubMed: 27901305
DOI: 10.1002/CHEM.201604515
Page generated: Sun Sep 29 03:29:30 2024
ISSN: ISSN 1521-3765
PubMed: 27901305
DOI: 10.1002/CHEM.201604515
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