Magnesium in PDB 5ftm: Cryo-Em Structure of Human P97 Bound to Atpgs (Conformation II)

All present enzymatic activity of Cryo-Em Structure of Human P97 Bound to Atpgs (Conformation II):
3.6.4.6;

The binding sites of Magnesium atom in the Cryo-Em Structure of Human P97 Bound to Atpgs (Conformation II) (pdb code 5ftm). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 6 binding sites of Magnesium where determined in the Cryo-Em Structure of Human P97 Bound to Atpgs (Conformation II), PDB code: 5ftm:
Jump to Magnesium binding site number: 1; 2; 3; 4; 5; 6;

Magnesium binding site 1 out of 6 in the Cryo-Em Structure of Human P97 Bound to Atpgs (Conformation II)


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Cryo-Em Structure of Human P97 Bound to Atpgs (Conformation II) within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg903 b:30.0 occ:1.00 OG1 A:THR525 2.3 25.0 1.0 O3B A:AGS901 2.5 46.3 1.0 O1A A:AGS901 2.6 46.1 1.0 O1B A:AGS901 3.4 39.1 1.0 O3G A:AGS901 3.4 47.6 1.0 CB A:THR525 3.4 29.6 1.0 PG A:AGS901 3.5 60.5 1.0 PB A:AGS901 3.5 41.9 1.0 PA A:AGS901 3.9 44.6 1.0 OD1 A:ASP577 4.1 63.1 1.0 OD2 A:ASP577 4.1 54.7 1.0 CG2 A:THR525 4.2 29.8 1.0 NH1 F:ARG635 4.2 64.6 1.0 O3A A:AGS901 4.2 41.4 1.0 CG A:ASP577 4.5 55.5 1.0 S1G A:AGS901 4.6 49.9 1.0 CA A:THR525 4.6 23.7 1.0 CD F:ARG635 4.6 59.3 1.0 N A:THR525 4.7 23.7 1.0 O5' A:AGS901 4.7 47.1 1.0 O2B A:AGS901 4.7 43.0 1.0 O2G A:AGS901 4.8 60.4 1.0 CZ F:ARG635 5.0 64.3 1.0

Magnesium binding site 2 out of 6 in the Cryo-Em Structure of Human P97 Bound to Atpgs (Conformation II)


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Cryo-Em Structure of Human P97 Bound to Atpgs (Conformation II) within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg903 b:30.0 occ:1.00 OG1 B:THR525 2.3 25.0 1.0 O3B B:AGS901 2.5 46.3 1.0 O1A B:AGS901 2.6 46.1 1.0 O1B B:AGS901 3.4 39.1 1.0 O3G B:AGS901 3.4 47.6 1.0 CB B:THR525 3.4 29.6 1.0 PG B:AGS901 3.5 60.5 1.0 PB B:AGS901 3.5 41.9 1.0 PA B:AGS901 3.9 44.6 1.0 OD1 B:ASP577 4.1 63.1 1.0 OD2 B:ASP577 4.1 54.7 1.0 CG2 B:THR525 4.2 29.8 1.0 NH1 A:ARG635 4.2 64.6 1.0 O3A B:AGS901 4.2 41.4 1.0 CG B:ASP577 4.5 55.5 1.0 S1G B:AGS901 4.6 49.9 1.0 CA B:THR525 4.6 23.7 1.0 CD A:ARG635 4.6 59.3 1.0 N B:THR525 4.7 23.7 1.0 O5' B:AGS901 4.7 47.1 1.0 O2B B:AGS901 4.7 43.0 1.0 O2G B:AGS901 4.8 60.4 1.0 CZ A:ARG635 5.0 64.3 1.0

Magnesium binding site 3 out of 6 in the Cryo-Em Structure of Human P97 Bound to Atpgs (Conformation II)


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of Cryo-Em Structure of Human P97 Bound to Atpgs (Conformation II) within 5.0Å range: probe atom residue distance (Å) B Occ C:Mg903 b:30.0 occ:1.00 OG1 C:THR525 2.3 25.0 1.0 O3B C:AGS901 2.5 46.3 1.0 O1A C:AGS901 2.6 46.1 1.0 O1B C:AGS901 3.4 39.1 1.0 O3G C:AGS901 3.4 47.6 1.0 CB C:THR525 3.4 29.6 1.0 PG C:AGS901 3.5 60.5 1.0 PB C:AGS901 3.5 41.9 1.0 PA C:AGS901 3.9 44.6 1.0 OD1 C:ASP577 4.1 63.1 1.0 OD2 C:ASP577 4.1 54.7 1.0 CG2 C:THR525 4.2 29.8 1.0 NH1 B:ARG635 4.2 64.6 1.0 O3A C:AGS901 4.2 41.4 1.0 CG C:ASP577 4.5 55.5 1.0 S1G C:AGS901 4.6 49.9 1.0 CA C:THR525 4.6 23.7 1.0 CD B:ARG635 4.6 59.3 1.0 N C:THR525 4.7 23.7 1.0 O5' C:AGS901 4.7 47.1 1.0 O2B C:AGS901 4.7 43.0 1.0 O2G C:AGS901 4.8 60.4 1.0 CZ B:ARG635 5.0 64.3 1.0

Magnesium binding site 4 out of 6 in the Cryo-Em Structure of Human P97 Bound to Atpgs (Conformation II)


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 4 of Cryo-Em Structure of Human P97 Bound to Atpgs (Conformation II) within 5.0Å range: probe atom residue distance (Å) B Occ D:Mg903 b:30.0 occ:1.00 OG1 D:THR525 2.3 25.0 1.0 O3B D:AGS901 2.5 46.3 1.0 O1A D:AGS901 2.6 46.1 1.0 O1B D:AGS901 3.4 39.1 1.0 O3G D:AGS901 3.4 47.6 1.0 CB D:THR525 3.4 29.6 1.0 PG D:AGS901 3.5 60.5 1.0 PB D:AGS901 3.5 41.9 1.0 PA D:AGS901 3.9 44.6 1.0 OD1 D:ASP577 4.1 63.1 1.0 OD2 D:ASP577 4.1 54.7 1.0 CG2 D:THR525 4.2 29.8 1.0 NH1 C:ARG635 4.2 64.6 1.0 O3A D:AGS901 4.2 41.4 1.0 CG D:ASP577 4.5 55.5 1.0 S1G D:AGS901 4.6 49.9 1.0 CA D:THR525 4.6 23.7 1.0 CD C:ARG635 4.6 59.3 1.0 N D:THR525 4.7 23.7 1.0 O5' D:AGS901 4.7 47.1 1.0 O2B D:AGS901 4.7 43.0 1.0 O2G D:AGS901 4.8 60.4 1.0 CZ C:ARG635 5.0 64.3 1.0

Magnesium binding site 5 out of 6 in the Cryo-Em Structure of Human P97 Bound to Atpgs (Conformation II)


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 5 of Cryo-Em Structure of Human P97 Bound to Atpgs (Conformation II) within 5.0Å range: probe atom residue distance (Å) B Occ E:Mg903 b:30.0 occ:1.00 OG1 E:THR525 2.3 25.0 1.0 O3B E:AGS901 2.5 46.3 1.0 O1A E:AGS901 2.6 46.1 1.0 O1B E:AGS901 3.4 39.1 1.0 O3G E:AGS901 3.4 47.6 1.0 CB E:THR525 3.4 29.6 1.0 PG E:AGS901 3.5 60.5 1.0 PB E:AGS901 3.5 41.9 1.0 PA E:AGS901 3.9 44.6 1.0 OD1 E:ASP577 4.1 63.1 1.0 OD2 E:ASP577 4.1 54.7 1.0 CG2 E:THR525 4.2 29.8 1.0 NH1 D:ARG635 4.2 64.6 1.0 O3A E:AGS901 4.2 41.4 1.0 CG E:ASP577 4.5 55.5 1.0 S1G E:AGS901 4.6 49.9 1.0 CA E:THR525 4.6 23.7 1.0 CD D:ARG635 4.6 59.3 1.0 N E:THR525 4.7 23.7 1.0 O5' E:AGS901 4.7 47.1 1.0 O2B E:AGS901 4.7 43.0 1.0 O2G E:AGS901 4.8 60.4 1.0 CZ D:ARG635 5.0 64.3 1.0

Magnesium binding site 6 out of 6 in the Cryo-Em Structure of Human P97 Bound to Atpgs (Conformation II)


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 6 of Cryo-Em Structure of Human P97 Bound to Atpgs (Conformation II) within 5.0Å range: probe atom residue distance (Å) B Occ F:Mg903 b:30.0 occ:1.00 OG1 F:THR525 2.3 25.0 1.0 O3B F:AGS901 2.5 46.3 1.0 O1A F:AGS901 2.6 46.1 1.0 O1B F:AGS901 3.4 39.1 1.0 O3G F:AGS901 3.4 47.6 1.0 CB F:THR525 3.4 29.6 1.0 PG F:AGS901 3.5 60.5 1.0 PB F:AGS901 3.5 41.9 1.0 PA F:AGS901 3.9 44.6 1.0 OD1 F:ASP577 4.1 63.1 1.0 OD2 F:ASP577 4.1 54.7 1.0 CG2 F:THR525 4.2 29.8 1.0 NH1 E:ARG635 4.2 64.6 1.0 O3A F:AGS901 4.2 41.4 1.0 CG F:ASP577 4.5 55.5 1.0 S1G F:AGS901 4.6 49.9 1.0 CA F:THR525 4.6 23.7 1.0 CD E:ARG635 4.6 59.3 1.0 N F:THR525 4.7 23.7 1.0 O5' F:AGS901 4.7 47.1 1.0 O2B F:AGS901 4.7 43.0 1.0 O2G F:AGS901 4.8 60.4 1.0 CZ E:ARG635 5.0 64.3 1.0

S.Banerjee, A.Bartesaghi, A.Merk, P.Rao, S.L.Bulfer, Y.Yan, N.Green, B.Mroczkowski, R.J.Neitz, P.Wipf, V.Falconieri, R.J.Deshaies, J.L.S.Milne, D.Huryn, M.Arkin, S.Subramaniam. 2.3 A Resolution Cryo-Em Structure of Human P97 and Mechanism of Allosteric Inhibition Science V. 351 871 2016.
ISSN: ISSN 0036-8075
PubMed: 26822609
DOI: 10.1126/SCIENCE.AAD7974