Magnesium in PDB 5fwl: Atomic Cryoem Structure of HSP90-CDC37-CDK4 Complex

The binding sites of Magnesium atom in the Atomic Cryoem Structure of HSP90-CDC37-CDK4 Complex (pdb code 5fwl). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Atomic Cryoem Structure of HSP90-CDC37-CDK4 Complex, PDB code: 5fwl:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Atomic Cryoem Structure of HSP90-CDC37-CDK4 Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Atomic Cryoem Structure of HSP90-CDC37-CDK4 Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1692 b:0.0 occ:1.00 OD1 A:ASN46 1.2 0.0 1.0 O2B A:ATP1691 2.0 0.0 1.0 O2A A:ATP1691 2.0 0.0 1.0 CG A:ASN46 2.3 0.0 1.0 O2G A:ATP1691 2.7 0.0 1.0 HD22 A:ASN46 2.8 0.0 1.0 ND2 A:ASN46 2.9 0.0 1.0 PA A:ATP1691 3.3 0.0 1.0 HA A:ASN46 3.3 0.0 1.0 PB A:ATP1691 3.4 0.0 1.0 CB A:ASN46 3.5 0.0 1.0 O5' A:ATP1691 3.5 0.0 1.0 CA A:ASN46 3.7 0.0 1.0 H A:ASN46 3.8 0.0 1.0 N A:ASN46 3.8 0.0 1.0 O A:GLU42 3.8 0.0 1.0 HB2 A:SER45 3.9 0.0 1.0 O3A A:ATP1691 3.9 0.0 1.0 HD21 A:ASN46 3.9 0.0 1.0 PG A:ATP1691 4.0 0.0 1.0 O3B A:ATP1691 4.1 0.0 1.0 HB3 A:ASN46 4.1 0.0 1.0 OD2 A:ASP49 4.1 0.0 1.0 OE1 A:GLU42 4.2 0.0 1.0 HB2 A:ASN46 4.3 0.0 1.0 HB3 A:SER45 4.3 0.0 1.0 C A:SER45 4.5 0.0 1.0 O1A A:ATP1691 4.5 0.0 1.0 HB3 A:GLU42 4.5 0.0 1.0 O1B A:ATP1691 4.6 0.0 1.0 HA3 A:GLY132 4.6 0.0 1.0 CB A:SER45 4.6 0.0 1.0 C5' A:ATP1691 4.6 0.0 1.0 O1G A:ATP1691 4.8 0.0 1.0 HA A:GLU42 4.8 0.0 1.0 O A:ILE126 4.8 0.0 1.0 C A:GLU42 4.9 0.0 1.0 O A:SER45 5.0 0.0 1.0 H A:PHE133 5.0 0.0 1.0

Magnesium binding site 2 out of 2 in the Atomic Cryoem Structure of HSP90-CDC37-CDK4 Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Atomic Cryoem Structure of HSP90-CDC37-CDK4 Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg1693 b:0.0 occ:1.00 OD1 B:ASN46 1.4 0.0 1.0 O2B B:ATP1692 2.0 0.0 1.0 O2A B:ATP1692 2.0 0.0 1.0 CG B:ASN46 2.2 0.0 1.0 O1B B:ATP1692 2.4 0.0 1.0 PB B:ATP1692 2.5 0.0 1.0 HD22 B:ASN46 2.6 0.0 1.0 ND2 B:ASN46 2.8 0.0 1.0 PA B:ATP1692 3.3 0.0 1.0 HA B:ASN46 3.4 0.0 1.0 O3A B:ATP1692 3.4 0.0 1.0 CB B:ASN46 3.5 0.0 1.0 O2G B:ATP1692 3.5 0.0 1.0 HD21 B:ASN46 3.6 0.0 1.0 HB3 B:ASN46 3.7 0.0 1.0 O3B B:ATP1692 3.8 0.0 1.0 CA B:ASN46 4.0 0.0 1.0 HG B:SER108 4.0 0.0 1.0 OD2 B:ASP49 4.0 0.0 1.0 HA3 B:GLY127 4.0 0.0 1.0 O5' B:ATP1692 4.1 0.0 1.0 HB2 B:ASN46 4.3 0.0 1.0 HA2 B:GLY127 4.4 0.0 1.0 PG B:ATP1692 4.4 0.0 1.0 HG1 B:THR110 4.4 0.0 1.0 N B:ASN46 4.5 0.0 1.0 O1A B:ATP1692 4.5 0.0 1.0 H B:ASN46 4.6 0.0 1.0 O B:ILE126 4.7 0.0 1.0 O B:GLU42 4.7 0.0 1.0 OG1 B:THR110 4.7 0.0 1.0 CA B:GLY127 4.8 0.0 1.0 OG B:SER108 4.8 0.0 1.0 HA3 B:GLY132 4.9 0.0 1.0

K.A.Verba, R.Y.Wang, A.Arakawa, Y.Liu, M.Shirouzu, S.Yokoyama, D.A.Agard. Atomic Structure of HSP90-CDC37-CDK4 Reveals That HSP90 Traps and Stabilizes An Unfolded Kinase. Science V. 352 1542 2016.
ISSN: ISSN 0036-8075
PubMed: 27339980
DOI: 10.1126/SCIENCE.AAF5023