Magnesium in PDB 5g15: Structure Aurora A (122-403) Bound to Activating Monobody MB1 and Amppcp

All present enzymatic activity of Structure Aurora A (122-403) Bound to Activating Monobody MB1 and Amppcp:
2.7.11.1;

The structure of Structure Aurora A (122-403) Bound to Activating Monobody MB1 and Amppcp, PDB code: 5g15 was solved by A.Zorba, S.Kutter, D.Kern, S.Koide, A.Koide, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	77.10 / 2.06
Space group	I 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	75.339, 91.361, 143.715, 90.00, 90.00, 90.00
R / Rfree (%)	22.7 / 27.4

The binding sites of Magnesium atom in the Structure Aurora A (122-403) Bound to Activating Monobody MB1 and Amppcp (pdb code 5g15). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Structure Aurora A (122-403) Bound to Activating Monobody MB1 and Amppcp, PDB code: 5g15:

Magnesium binding site 1 out of 1 in the Structure Aurora A (122-403) Bound to Activating Monobody MB1 and Amppcp


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Structure Aurora A (122-403) Bound to Activating Monobody MB1 and Amppcp within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1392 b:44.7 occ:1.00 O3G A:ACP1391 2.4 63.6 1.0 OD1 A:ASP274 2.5 30.9 1.0 O A:HOH2026 2.7 28.9 1.0 O A:HOH2019 2.8 38.7 1.0 CG A:ASP274 3.4 32.2 1.0 OE2 A:GLU181 3.5 36.0 1.0 PG A:ACP1391 3.6 79.3 1.0 OE1 A:GLU181 3.6 31.8 1.0 CB A:ASP274 3.6 27.1 1.0 NZ A:LYS162 3.7 32.5 1.0 CA A:ASP274 3.8 23.1 1.0 O1G A:ACP1391 3.9 67.2 1.0 CD A:GLU181 3.9 31.4 1.0 O A:HOH2132 4.2 41.2 1.0 C3B A:ACP1391 4.3 58.7 1.0 OD2 A:ASP274 4.6 37.6 1.0 O1A A:ACP1391 4.7 40.1 1.0 N A:ASP274 4.7 20.5 1.0 C A:ASP274 4.8 20.8 1.0 O2G A:ACP1391 4.8 60.2 1.0 CE A:LYS162 4.9 28.9 1.0

A.Zorba, V.Nguyen, A.Koide, M.Hoemberger, Y.Zheng, S.Kutter, C.Kim, S.Koide, D.Kern. Allosteric Modulation of A Human Protein Kinase with Monobodies. Proc.Natl.Acad.Sci.Usa V. 116 13937 2019.
ISSN: ESSN 1091-6490
PubMed: 31239342
DOI: 10.1073/PNAS.1906024116