Magnesium in PDB 5hem: Crystal Structure of the N-Terminus D161Y Bromodomain Mutant of Human BRD2

The structure of Crystal Structure of the N-Terminus D161Y Bromodomain Mutant of Human BRD2, PDB code: 5hem was solved by C.Tallant, C.Lori, A.Pasquo, R.Chiaraluce, V.Consalvi, J.A.Newman, F.Vondelft, C.H.Arrowsmith, A.M.Edwards, C.Bountra, S.Knapp, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.67 / 1.65
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	68.730, 68.730, 113.364, 90.00, 90.00, 90.00
R / Rfree (%)	16.7 / 19.9

The binding sites of Magnesium atom in the Crystal Structure of the N-Terminus D161Y Bromodomain Mutant of Human BRD2 (pdb code 5hem). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Crystal Structure of the N-Terminus D161Y Bromodomain Mutant of Human BRD2, PDB code: 5hem:

Magnesium binding site 1 out of 1 in the Crystal Structure of the N-Terminus D161Y Bromodomain Mutant of Human BRD2


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of the N-Terminus D161Y Bromodomain Mutant of Human BRD2 within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg201 b:12.6 occ:1.00 O A:HOH338 2.3 8.8 1.0 O A:HOH331 2.4 12.4 1.0 O A:HOH366 3.4 10.6 1.0 CE2 A:TYR153 4.3 8.0 1.0 OE1 A:GLU170 4.3 9.5 1.0 CD2 A:TYR153 4.5 8.3 1.0 OE2 A:GLU170 4.6 10.7 1.0 CD A:GLU170 4.9 9.2 1.0 CZ A:TYR153 4.9 7.8 1.0

C.Tallant, C.Lori, A.Pasquo, R.Chiaraluce, V.Consalvi, J.A.Newman, F.Von Delft, C.H.Arrowsmith, A.M.Edwards, C.Bountra, S.Knapp. Crystal Structure of the N-Terminus D161Y Bromodomain Mutant of Human BRD2 To Be Published.