Atomistry » Magnesium » PDB 5hr6-5i8q » 5hvk
Atomistry »
  Magnesium »
    PDB 5hr6-5i8q »
      5hvk »

Magnesium in PDB 5hvk: Crystal Structure of LIMK1 Mutant D460N in Complex with Full-Length Cofilin-1

Enzymatic activity of Crystal Structure of LIMK1 Mutant D460N in Complex with Full-Length Cofilin-1

All present enzymatic activity of Crystal Structure of LIMK1 Mutant D460N in Complex with Full-Length Cofilin-1:
2.7.11.1;

Protein crystallography data

The structure of Crystal Structure of LIMK1 Mutant D460N in Complex with Full-Length Cofilin-1, PDB code: 5hvk was solved by S.Hamill, T.J.Boggon, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 48.11 / 3.50
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 81.116, 102.283, 141.900, 90.00, 90.00, 90.00
R / Rfree (%) 27.3 / 31

Magnesium Binding Sites:

The binding sites of Magnesium atom in the Crystal Structure of LIMK1 Mutant D460N in Complex with Full-Length Cofilin-1 (pdb code 5hvk). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Crystal Structure of LIMK1 Mutant D460N in Complex with Full-Length Cofilin-1, PDB code: 5hvk:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in 5hvk

Go back to Magnesium Binding Sites List in 5hvk
Magnesium binding site 1 out of 2 in the Crystal Structure of LIMK1 Mutant D460N in Complex with Full-Length Cofilin-1


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of LIMK1 Mutant D460N in Complex with Full-Length Cofilin-1 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mg1002

b:19.4
occ:1.00
O3' A:ANP1001 2.1 36.0 1.0
O A:HIS464 2.4 37.6 1.0
C3' A:ANP1001 2.6 38.7 1.0
OD1 A:ASN465 3.1 20.3 1.0
C A:HIS464 3.6 25.3 1.0
C2' A:ANP1001 3.7 20.4 1.0
O2B A:ANP1001 3.8 70.1 1.0
C4' A:ANP1001 3.9 42.3 1.0
CG2 A:THR420 4.1 20.9 1.0
CA A:ASN465 4.2 19.4 1.0
C5' A:ANP1001 4.2 38.0 1.0
CG A:ASN465 4.2 21.1 1.0
O2' A:ANP1001 4.3 24.1 1.0
N A:ASN465 4.4 20.1 1.0
O3A A:ANP1001 4.4 62.7 1.0
PB A:ANP1001 4.5 70.1 1.0
O1B A:ANP1001 4.5 70.5 1.0
CA A:HIS464 4.6 18.3 1.0
CB A:HIS464 4.7 22.4 1.0
CB A:ASN465 4.8 18.0 1.0
O5' A:ANP1001 4.8 44.2 1.0
C1' A:ANP1001 4.9 24.9 1.0
O4' A:ANP1001 5.0 33.5 1.0

Magnesium binding site 2 out of 2 in 5hvk

Go back to Magnesium Binding Sites List in 5hvk
Magnesium binding site 2 out of 2 in the Crystal Structure of LIMK1 Mutant D460N in Complex with Full-Length Cofilin-1


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Crystal Structure of LIMK1 Mutant D460N in Complex with Full-Length Cofilin-1 within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Mg702

b:36.7
occ:1.00
OD1 C:ASN465 2.8 21.0 1.0
C3' C:ANP701 3.3 29.8 1.0
O C:HIS464 3.7 30.6 1.0
O3' C:ANP701 3.7 22.2 1.0
C5' C:ANP701 3.8 33.5 1.0
CG C:ASN465 3.8 20.6 1.0
O2B C:ANP701 3.9 65.1 1.0
C8 C:ANP701 3.9 22.9 1.0
C4' C:ANP701 4.1 28.3 1.0
CA C:ASN465 4.2 13.3 1.0
CB C:ASN465 4.3 14.3 1.0
C2' C:ANP701 4.4 30.6 1.0
O1B C:ANP701 4.5 80.6 1.0
PB C:ANP701 4.6 72.7 1.0
N7 C:ANP701 4.6 32.6 1.0
C C:HIS464 4.7 16.5 1.0
O3A C:ANP701 4.7 76.3 1.0
ND2 C:ASN465 4.8 30.1 1.0
CB C:ALA477 4.8 11.1 1.0
O2A C:ANP701 4.8 55.6 1.0
N9 C:ANP701 4.8 21.2 1.0
CB C:ASP478 4.8 21.7 1.0
O5' C:ANP701 4.8 39.0 1.0
N C:ASN465 4.9 13.5 1.0
NZ C:LYS368 5.0 52.5 1.0

Reference:

S.Hamill, H.J.Lou, B.E.Turk, T.J.Boggon. Structural Basis For Noncanonical Substrate Recognition of Cofilin/Adf Proteins By Lim Kinases. Mol.Cell V. 62 397 2016.
ISSN: ISSN 1097-2765
PubMed: 27153537
DOI: 10.1016/J.MOLCEL.2016.04.001
Page generated: Mon Dec 14 20:28:58 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy