Magnesium in PDB 5iy8: Human Holo-Pic in the Initial Transcribing State

All present enzymatic activity of Human Holo-Pic in the Initial Transcribing State:
2.7.7.48; 2.7.7.6; 3.6.4.12;

The structure of Human Holo-Pic in the Initial Transcribing State also contains other interesting chemical elements:

Zinc

(Zn)

11 atoms

The binding sites of Magnesium atom in the Human Holo-Pic in the Initial Transcribing State (pdb code 5iy8). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Human Holo-Pic in the Initial Transcribing State, PDB code: 5iy8:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Human Holo-Pic in the Initial Transcribing State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Human Holo-Pic in the Initial Transcribing State within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg2001 b:0.0 occ:1.00 OD2 A:ASP495 2.5 0.0 1.0 OD2 A:ASP499 2.9 0.0 1.0 CG A:ASP495 3.1 0.0 1.0 O A:ASN493 3.3 0.0 1.0 CB A:ASP495 3.5 0.0 1.0 N A:ASP495 3.6 0.0 1.0 C A:ALA494 3.9 0.0 1.0 CG A:ASP499 4.0 0.0 1.0 OD1 A:ASP495 4.1 0.0 1.0 CA A:ASP495 4.1 0.0 1.0 OD2 U:ASP282 4.2 0.0 1.0 C A:ASN493 4.4 0.0 1.0 CA A:ALA494 4.4 0.0 1.0 O A:ALA494 4.4 0.0 1.0 OD1 A:ASP497 4.5 0.0 1.0 OD1 A:ASP499 4.5 0.0 1.0 O U:ALA281 4.8 0.0 1.0 N A:ALA494 4.8 0.0 1.0 OD2 A:ASP497 4.8 0.0 1.0

Magnesium binding site 2 out of 2 in the Human Holo-Pic in the Initial Transcribing State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Human Holo-Pic in the Initial Transcribing State within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg2002 b:0.0 occ:1.00 OD1 U:ASP282 2.0 0.0 1.0 OD1 A:ASP495 2.1 0.0 1.0 OE2 B:GLU791 2.6 0.0 1.0 CG U:ASP282 3.2 0.0 1.0 CG A:ASP495 3.3 0.0 1.0 O A:ALA494 3.4 0.0 1.0 CD B:GLU791 3.4 0.0 1.0 OD2 A:ASP495 3.8 0.0 1.0 CG B:GLU791 3.9 0.0 1.0 OD2 U:ASP282 4.0 0.0 1.0 CB U:ASP282 4.2 0.0 1.0 OG1 A:THR489 4.2 0.0 1.0 O U:ALA281 4.3 0.0 1.0 OE1 B:GLU791 4.4 0.0 1.0 CB A:ASP495 4.5 0.0 1.0 C A:ALA494 4.5 0.0 1.0 CA U:ASP282 4.6 0.0 1.0 CA A:ASP495 4.7 0.0 1.0

Y.He, C.Yan, J.Fang, C.Inouye, R.Tjian, I.Ivanov, E.Nogales. Near-Atomic Resolution Visualization of Human Transcription Promoter Opening. Nature V. 533 359 2016.
ISSN: ESSN 1476-4687
PubMed: 27193682
DOI: 10.1038/NATURE17970