Magnesium in PDB 5jxs: Mutant GC216/7AA of 3D Polymerase From Foot-and-Mouth Disease Virus

All present enzymatic activity of Mutant GC216/7AA of 3D Polymerase From Foot-and-Mouth Disease Virus:
2.7.7.48;

The structure of Mutant GC216/7AA of 3D Polymerase From Foot-and-Mouth Disease Virus, PDB code: 5jxs was solved by N.Verdaguer, C.Ferrer-Orta, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	43.10 / 2.80
Space group	P 32 2 1
Cell size a, b, c (Å), α, β, γ (°)	95.778, 95.778, 100.875, 90.00, 90.00, 120.00
R / Rfree (%)	20.5 / 26.4

The binding sites of Magnesium atom in the Mutant GC216/7AA of 3D Polymerase From Foot-and-Mouth Disease Virus (pdb code 5jxs). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Mutant GC216/7AA of 3D Polymerase From Foot-and-Mouth Disease Virus, PDB code: 5jxs:

Magnesium binding site 1 out of 1 in the Mutant GC216/7AA of 3D Polymerase From Foot-and-Mouth Disease Virus


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Mutant GC216/7AA of 3D Polymerase From Foot-and-Mouth Disease Virus within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg501 b:61.8 occ:1.00 O A:HOH604 2.1 60.5 1.0 OD1 A:ASP240 2.7 74.5 1.0 O A:HOH603 2.7 48.1 1.0 OD1 A:ASP339 2.9 48.6 1.0 O A:VAL239 2.9 54.6 1.0 OD1 A:ASP238 3.1 81.7 1.0 O A:ILE340 3.8 53.7 1.0 CG A:ASP339 3.8 44.5 1.0 CG A:ASP240 3.9 69.0 1.0 N A:ILE340 3.9 60.9 1.0 C A:VAL239 4.0 51.2 1.0 CA A:ASP339 4.2 39.2 1.0 CG A:ASP238 4.2 76.6 1.0 O A:THR384 4.4 53.3 1.0 CA A:ASP240 4.5 50.9 1.0 OD2 A:ASP339 4.6 46.2 1.0 C A:ASP339 4.6 52.6 1.0 CB A:ASP339 4.6 34.3 1.0 N A:ASP240 4.7 51.7 1.0 N A:VAL239 4.7 54.0 1.0 OD2 A:ASP240 4.7 78.3 1.0 OD2 A:ASP238 4.7 80.5 1.0 C A:ILE340 4.7 47.4 1.0 CG2 A:ILE340 4.8 59.0 1.0 CB A:ASP240 4.8 50.9 1.0 CA A:ILE340 4.9 52.2 1.0 C A:ASP238 4.9 61.7 1.0

M.R.Herod, C.Ferrer-Orta, E.A.Loundras, J.C.Ward, N.Verdaguer, D.J.Rowlands, N.J.Stonehouse. Both Cis and Trans Activities of Foot-and-Mouth Disease Virus 3D Polymerase Are Essential For Viral Rna Replication. J.Virol. V. 90 6864 2016.
ISSN: ESSN 1098-5514
PubMed: 27194768
DOI: 10.1128/JVI.00469-16