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Magnesium in PDB 5k0k: Crystal Structure of the Catalytic Domain of the Proto-Oncogene Tyrosine-Protein Kinase Mer in Complex with Inhibitor UNC2434Enzymatic activity of Crystal Structure of the Catalytic Domain of the Proto-Oncogene Tyrosine-Protein Kinase Mer in Complex with Inhibitor UNC2434
All present enzymatic activity of Crystal Structure of the Catalytic Domain of the Proto-Oncogene Tyrosine-Protein Kinase Mer in Complex with Inhibitor UNC2434:
2.7.10.1; Protein crystallography data
The structure of Crystal Structure of the Catalytic Domain of the Proto-Oncogene Tyrosine-Protein Kinase Mer in Complex with Inhibitor UNC2434, PDB code: 5k0k
was solved by
X.Wang,
J.Liu,
W.Zhang,
M.A.Stashko,
J.Nichols,
D.Deryckere,
M.J.Miley,
J.Norris-Drouin,
Z.Chen,
M.Machius,
E.Wood,
D.K.Graham,
H.S.Earp,
K.Graham,
D.Kireev,
S.V.Frye,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5k0k:
The structure of Crystal Structure of the Catalytic Domain of the Proto-Oncogene Tyrosine-Protein Kinase Mer in Complex with Inhibitor UNC2434 also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Crystal Structure of the Catalytic Domain of the Proto-Oncogene Tyrosine-Protein Kinase Mer in Complex with Inhibitor UNC2434
(pdb code 5k0k). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Crystal Structure of the Catalytic Domain of the Proto-Oncogene Tyrosine-Protein Kinase Mer in Complex with Inhibitor UNC2434, PDB code: 5k0k: Magnesium binding site 1 out of 1 in 5k0kGo back to Magnesium Binding Sites List in 5k0k
Magnesium binding site 1 out
of 1 in the Crystal Structure of the Catalytic Domain of the Proto-Oncogene Tyrosine-Protein Kinase Mer in Complex with Inhibitor UNC2434
Mono view Stereo pair view
Reference:
X.Wang,
J.Liu,
W.Zhang,
M.A.Stashko,
J.Nichols,
M.J.Miley,
J.Norris-Drouin,
Z.Chen,
M.Machius,
D.Deryckere,
E.Wood,
D.K.Graham,
H.S.Earp,
D.Kireev,
S.V.Frye.
Design and Synthesis of Novel Macrocyclic Mer Tyrosine Kinase Inhibitors. Acs Med Chem Lett V. 7 1044 2016.
Page generated: Mon Dec 14 20:36:39 2020
ISSN: ISSN 1948-5875 PubMed: 27994735 DOI: 10.1021/ACSMEDCHEMLETT.6B00221 |
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