Magnesium in PDB 5l6d: Crystal Structure of the Human METTL3-METTL14 Complex Bound to Sah

All present enzymatic activity of Crystal Structure of the Human METTL3-METTL14 Complex Bound to Sah:
2.1.1.62;

The structure of Crystal Structure of the Human METTL3-METTL14 Complex Bound to Sah, PDB code: 5l6d was solved by P.Sledz, M.Jinek, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.63 / 1.85
Space group	P 32 2 1
Cell size a, b, c (Å), α, β, γ (°)	63.822, 63.822, 225.626, 90.00, 90.00, 120.00
R / Rfree (%)	15.7 / 19.2

The binding sites of Magnesium atom in the Crystal Structure of the Human METTL3-METTL14 Complex Bound to Sah (pdb code 5l6d). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Crystal Structure of the Human METTL3-METTL14 Complex Bound to Sah, PDB code: 5l6d:

Magnesium binding site 1 out of 1 in the Crystal Structure of the Human METTL3-METTL14 Complex Bound to Sah


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of the Human METTL3-METTL14 Complex Bound to Sah within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg602 b:43.7 occ:1.00 O A:HOH853 2.1 39.3 1.0 O A:HOH705 2.1 33.1 1.0 O A:HOH825 2.5 31.3 1.0 H A:GLY493 3.8 28.8 1.0 OE1 A:GLN496 3.8 34.3 1.0 O A:PHE494 3.9 28.1 1.0 O A:HOH828 4.1 45.7 1.0 O B:HOH675 4.1 43.8 1.0 H A:PHE494 4.2 29.6 1.0 HA A:GLN492 4.3 27.2 1.0 CD A:GLN496 4.5 38.3 1.0 N A:GLY493 4.5 24.0 1.0 O A:PRO491 4.6 31.0 1.0 HG3 A:GLN496 4.7 36.3 1.0 HB2 A:GLN496 4.7 28.5 1.0 N A:PHE494 4.8 24.6 1.0 HB2 A:PHE494 4.8 21.7 1.0 H A:GLN496 4.9 29.9 1.0 O B:HOH660 5.0 51.6 1.0 C A:PHE494 5.0 30.0 1.0

P.Sledz, M.Jinek. Structural Insights Into the Molecular Mechanism of the M(6)A Writer Complex. Elife V. 5 2016.
ISSN: ESSN 2050-084X
PubMed: 27627798
DOI: 10.7554/ELIFE.18434