Magnesium in PDB 5ls9: Humanized Archaeal Ferritin

The structure of Humanized Archaeal Ferritin, PDB code: 5ls9 was solved by P.Baiocco, M.C.Trabuco, A.Boffi, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.69 / 2.93
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	185.797, 190.650, 176.537, 90.00, 90.00, 90.00
R / Rfree (%)	27.7 / 30.2

The binding sites of Magnesium atom in the Humanized Archaeal Ferritin (pdb code 5ls9). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Humanized Archaeal Ferritin, PDB code: 5ls9:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Humanized Archaeal Ferritin


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Humanized Archaeal Ferritin within 5.0Å range: probe atom residue distance (Å) B Occ F:Mg201 b:64.8 occ:1.00 OE1 F:GLU19 2.4 66.5 1.0 OE1 F:GLU52 2.5 67.4 1.0 OE2 F:GLU19 2.7 69.8 1.0 O F:HOH302 2.9 63.6 1.0 CD F:GLU19 2.9 68.4 1.0 OE1 F:GLN129 2.9 81.1 1.0 CD F:GLU52 3.3 66.9 1.0 ND1 F:HIS55 3.3 80.4 1.0 OE2 F:GLU52 3.4 63.7 1.0 CE1 F:HIS55 4.1 82.3 1.0 CD F:GLN129 4.1 78.8 1.0 CG1 F:VAL99 4.1 70.2 1.0 CG F:HIS55 4.3 81.3 1.0 CG F:GLU19 4.4 66.2 1.0 CB F:HIS55 4.5 77.0 1.0 OE1 F:GLU96 4.7 69.1 1.0 OE2 F:GLU132 4.7 74.0 1.0 CG F:GLU52 4.7 65.5 1.0 NE2 F:GLN129 5.0 77.7 1.0

Magnesium binding site 2 out of 2 in the Humanized Archaeal Ferritin


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Humanized Archaeal Ferritin within 5.0Å range: probe atom residue distance (Å) B Occ I:Mg201 b:51.7 occ:1.00 OE1 I:GLU52 2.3 74.0 1.0 O I:HOH301 2.5 40.5 1.0 OE2 I:GLU52 2.7 71.1 1.0 OE1 I:GLN129 2.7 63.1 1.0 CD I:GLU52 2.9 71.8 1.0 OE1 I:GLU19 3.1 68.6 1.0 OE2 I:GLU132 3.2 78.8 1.0 OE1 I:GLU96 3.3 72.6 1.0 OE2 I:GLU19 3.7 69.7 1.0 CD I:GLU19 3.8 67.5 1.0 CD I:GLN129 3.9 66.9 1.0 OE2 I:GLU96 3.9 66.0 1.0 CD I:GLU132 3.9 81.0 1.0 CD I:GLU96 4.0 68.7 1.0 CG1 I:VAL99 4.2 75.1 1.0 ND1 I:HIS55 4.2 66.5 1.0 OE1 I:GLU132 4.2 78.5 1.0 CG I:GLU52 4.3 68.2 1.0 NE2 I:GLN129 4.5 69.4 1.0 CE1 I:HIS55 4.8 66.6 1.0 CG I:GLU132 5.0 79.5 1.0

V.De Turris, M.Cardoso Trabuco, G.Peruzzi, A.Boffi, C.Testi, B.Vallone, L.Celeste Montemiglio, A.D.Georges, L.Calisti, I.Benni, A.Bonamore, P.Baiocco. Humanized Archaeal Ferritin As A Tool For Cell Targeted Delivery. Nanoscale V. 9 647 2017.
ISSN: ISSN 2040-3372
PubMed: 27942679
DOI: 10.1039/C6NR07129E