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Magnesium in PDB 5m4k: Application of Off-Rate Screening in the Identification of Novel Pan- Isoform Inhibitors of Pyruvate Dehydrogenase KinaseEnzymatic activity of Application of Off-Rate Screening in the Identification of Novel Pan- Isoform Inhibitors of Pyruvate Dehydrogenase Kinase
All present enzymatic activity of Application of Off-Rate Screening in the Identification of Novel Pan- Isoform Inhibitors of Pyruvate Dehydrogenase Kinase:
2.7.11.2; Protein crystallography data
The structure of Application of Off-Rate Screening in the Identification of Novel Pan- Isoform Inhibitors of Pyruvate Dehydrogenase Kinase, PDB code: 5m4k
was solved by
L.M.Baker,
P.Brough,
A.Surgenor,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5m4k:
The structure of Application of Off-Rate Screening in the Identification of Novel Pan- Isoform Inhibitors of Pyruvate Dehydrogenase Kinase also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Application of Off-Rate Screening in the Identification of Novel Pan- Isoform Inhibitors of Pyruvate Dehydrogenase Kinase
(pdb code 5m4k). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Application of Off-Rate Screening in the Identification of Novel Pan- Isoform Inhibitors of Pyruvate Dehydrogenase Kinase, PDB code: 5m4k: Magnesium binding site 1 out of 1 in 5m4kGo back to Magnesium Binding Sites List in 5m4k
Magnesium binding site 1 out
of 1 in the Application of Off-Rate Screening in the Identification of Novel Pan- Isoform Inhibitors of Pyruvate Dehydrogenase Kinase
Mono view Stereo pair view
Reference:
P.A.Brough,
L.Baker,
S.Bedford,
K.Brown,
S.Chavda,
V.Chell,
J.D'alessandro,
N.G.Davies,
B.Davis,
L.Le Strat,
A.T.Macias,
D.Maddox,
P.C.Mahon,
A.J.Massey,
N.Matassova,
S.Mckenna,
J.W.Meissner,
J.D.Moore,
J.B.Murray,
C.J.Northfield,
C.Parry,
R.Parsons,
S.D.Roughley,
T.Shaw,
H.Simmonite,
S.Stokes,
A.Surgenor,
E.Stefaniak,
A.Robertson,
Y.Wang,
P.Webb,
N.Whitehead,
M.Wood.
Application of Off-Rate Screening in the Identification of Novel Pan-Isoform Inhibitors of Pyruvate Dehydrogenase Kinase. J. Med. Chem. V. 60 2271 2017.
Page generated: Mon Dec 14 20:50:18 2020
ISSN: ISSN 1520-4804 PubMed: 28199108 DOI: 10.1021/ACS.JMEDCHEM.6B01478 |
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