Magnesium in PDB 5mpa: 26S Proteasome in Presence of Atp (S2)

All present enzymatic activity of 26S Proteasome in Presence of Atp (S2):
3.4.25.1;

The binding sites of Magnesium atom in the 26S Proteasome in Presence of Atp (S2) (pdb code 5mpa). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 6 binding sites of Magnesium where determined in the 26S Proteasome in Presence of Atp (S2), PDB code: 5mpa:
Jump to Magnesium binding site number: 1; 2; 3; 4; 5; 6;

Magnesium binding site 1 out of 6 in the 26S Proteasome in Presence of Atp (S2)


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of 26S Proteasome in Presence of Atp (S2) within 5.0Å range: probe atom residue distance (Å) B Occ H:Mg501 b:1.0 occ:1.00 OG1 H:THR257 1.9 1.0 1.0 O2B H:ATP502 2.6 1.0 1.0 O2G H:ATP502 2.6 1.0 1.0 CB H:THR257 3.3 1.0 1.0 N H:THR257 3.8 1.0 1.0 PB H:ATP502 3.9 1.0 1.0 PG H:ATP502 4.0 1.0 1.0 OE1 H:GLU310 4.1 1.0 1.0 CA H:THR257 4.1 1.0 1.0 CG2 H:THR257 4.2 1.0 1.0 CB H:LYS256 4.2 1.0 1.0 O3B H:ATP502 4.3 1.0 1.0 CE H:LYS256 4.5 1.0 1.0 C H:LYS256 4.6 1.0 1.0 O1B H:ATP502 4.6 1.0 1.0 CB H:ALA354 4.7 1.0 1.0 CA H:LYS256 4.9 1.0 1.0

Magnesium binding site 2 out of 6 in the 26S Proteasome in Presence of Atp (S2)


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of 26S Proteasome in Presence of Atp (S2) within 5.0Å range: probe atom residue distance (Å) B Occ I:Mg502 b:1.0 occ:1.00 OG1 I:THR230 1.8 1.0 1.0 CB I:THR230 2.9 1.0 1.0 O2B I:ATP501 2.9 1.0 1.0 CG2 I:THR230 3.2 1.0 1.0 O2G I:ATP501 3.2 1.0 1.0 CA I:THR230 3.7 1.0 1.0 N I:THR230 3.8 1.0 1.0 PB I:ATP501 4.1 1.0 1.0 PG I:ATP501 4.1 1.0 1.0 O3B I:ATP501 4.2 1.0 1.0 OD1 I:ASP282 4.2 1.0 1.0 OE1 J:GLU274 4.4 1.0 1.0 O3G I:ATP501 4.6 1.0 1.0 OD2 I:ASP282 4.7 1.0 1.0 O1A I:ATP501 4.8 1.0 1.0 C I:LYS229 4.8 1.0 1.0 CG I:ASP282 4.9 1.0 1.0 O3A I:ATP501 4.9 1.0 1.0 PA I:ATP501 4.9 1.0 1.0 O2A I:ATP501 5.0 1.0 1.0

Magnesium binding site 3 out of 6 in the 26S Proteasome in Presence of Atp (S2)


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of 26S Proteasome in Presence of Atp (S2) within 5.0Å range: probe atom residue distance (Å) B Occ K:Mg502 b:1.0 occ:1.00 O1G K:ATP501 2.0 1.0 1.0 OG1 K:THR220 2.3 1.0 1.0 O1B K:ATP501 2.9 1.0 1.0 PG K:ATP501 2.9 1.0 1.0 O3B K:ATP501 3.4 1.0 1.0 O2G K:ATP501 3.5 1.0 1.0 CB K:THR220 3.6 1.0 1.0 PB K:ATP501 3.7 1.0 1.0 O3A K:ATP501 4.1 1.0 1.0 O3G K:ATP501 4.2 1.0 1.0 N K:THR220 4.3 1.0 1.0 CA K:THR220 4.5 1.0 1.0 OE2 K:GLU273 4.5 1.0 1.0 CG2 K:THR220 4.6 1.0 1.0 O K:ASP272 4.6 1.0 1.0 O L:ASP313 4.8 1.0 1.0 CA L:GLY314 5.0 1.0 1.0

Magnesium binding site 4 out of 6 in the 26S Proteasome in Presence of Atp (S2)


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 4 of 26S Proteasome in Presence of Atp (S2) within 5.0Å range: probe atom residue distance (Å) B Occ L:Mg502 b:1.0 occ:1.00 OG1 L:THR229 2.1 1.0 1.0 O2G L:ATP501 2.7 1.0 1.0 O2B L:ATP501 2.8 1.0 1.0 CB L:THR229 3.3 1.0 1.0 CG2 L:THR229 3.6 1.0 1.0 OE2 L:GLU282 3.8 1.0 1.0 PG L:ATP501 4.1 1.0 1.0 PB L:ATP501 4.2 1.0 1.0 CA L:THR229 4.4 1.0 1.0 O1A L:ATP501 4.5 1.0 1.0 O3B L:ATP501 4.6 1.0 1.0 N L:THR229 4.6 1.0 1.0 O3G L:ATP501 4.6 1.0 1.0 CD L:GLU282 4.8 1.0 1.0

Magnesium binding site 5 out of 6 in the 26S Proteasome in Presence of Atp (S2)


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 5 of 26S Proteasome in Presence of Atp (S2) within 5.0Å range: probe atom residue distance (Å) B Occ M:Mg502 b:1.0 occ:1.00 OG1 M:THR229 1.8 1.0 1.0 CB M:THR229 2.5 1.0 1.0 O1B M:ATP501 2.6 1.0 1.0 O2G M:ATP501 2.7 1.0 1.0 CG2 M:THR229 3.3 1.0 1.0 CA M:THR229 3.8 1.0 1.0 N M:THR229 3.9 1.0 1.0 PB M:ATP501 4.0 1.0 1.0 OD2 H:ASP341 4.1 1.0 1.0 PG M:ATP501 4.1 1.0 1.0 OD1 M:ASP281 4.2 1.0 1.0 OD1 H:ASP341 4.3 1.0 1.0 CG H:ASP341 4.4 1.0 1.0 OE1 M:GLU282 4.5 1.0 1.0 O3B M:ATP501 4.5 1.0 1.0 O1G M:ATP501 4.7 1.0 1.0 O2A M:ATP501 4.8 1.0 1.0 O3A M:ATP501 4.8 1.0 1.0 O1A M:ATP501 4.8 1.0 1.0 PA M:ATP501 4.9 1.0 1.0 NZ M:LYS228 4.9 1.0 1.0 O2B M:ATP501 5.0 1.0 1.0

Magnesium binding site 6 out of 6 in the 26S Proteasome in Presence of Atp (S2)


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 6 of 26S Proteasome in Presence of Atp (S2) within 5.0Å range: probe atom residue distance (Å) B Occ J:Mg502 b:1.0 occ:1.00 OG1 J:THR196 2.0 1.0 1.0 O3B J:ADP501 2.1 1.0 1.0 CB J:THR196 3.4 1.0 1.0 PB J:ADP501 3.6 1.0 1.0 OD2 J:ASP248 3.9 1.0 1.0 CG2 J:THR196 4.2 1.0 1.0 N J:THR196 4.3 1.0 1.0 O1B J:ADP501 4.3 1.0 1.0 O3A J:ADP501 4.3 1.0 1.0 O2B J:ADP501 4.3 1.0 1.0 CA J:THR196 4.4 1.0 1.0 O2A J:ADP501 4.4 1.0 1.0 CE2 J:PHE246 4.5 1.0 1.0 CZ J:PHE246 4.7 1.0 1.0 PA J:ADP501 4.7 1.0 1.0 CE J:LYS195 4.7 1.0 1.0 O1A J:ADP501 4.9 1.0 1.0 CG J:ASP248 4.9 1.0 1.0

M.Wehmer, T.Rudack, F.Beck, A.Aufderheide, G.Pfeifer, J.M.Plitzko, F.Forster, K.Schulten, W.Baumeister, E.Sakata. Structural Insights Into the Functional Cycle of the Atpase Module of the 26S Proteasome. Proc. Natl. Acad. Sci. V. 114 1305 2017U.S.A..
ISSN: ESSN 1091-6490
PubMed: 28115689
DOI: 10.1073/PNAS.1621129114