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Atomistry » Magnesium » PDB 5mtv-5n77 » 5mwa » |
Magnesium in PDB 5mwa: Human Seh Phosphatase in Complex with 3-4-3,4-Dichlorophenyl-5-Phenyl- 1,3-Oxazol-2-Yl-Benzoic-AcidEnzymatic activity of Human Seh Phosphatase in Complex with 3-4-3,4-Dichlorophenyl-5-Phenyl- 1,3-Oxazol-2-Yl-Benzoic-Acid
All present enzymatic activity of Human Seh Phosphatase in Complex with 3-4-3,4-Dichlorophenyl-5-Phenyl- 1,3-Oxazol-2-Yl-Benzoic-Acid:
3.1.3.76; 3.3.2.10; Protein crystallography data
The structure of Human Seh Phosphatase in Complex with 3-4-3,4-Dichlorophenyl-5-Phenyl- 1,3-Oxazol-2-Yl-Benzoic-Acid, PDB code: 5mwa
was solved by
J.S.Kramer,
D.Pogoryelov,
F.J.Sorrell,
N.Fox,
A.Chaikuad,
S.Knapp,
E.Proschak,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5mwa:
The structure of Human Seh Phosphatase in Complex with 3-4-3,4-Dichlorophenyl-5-Phenyl- 1,3-Oxazol-2-Yl-Benzoic-Acid also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Human Seh Phosphatase in Complex with 3-4-3,4-Dichlorophenyl-5-Phenyl- 1,3-Oxazol-2-Yl-Benzoic-Acid
(pdb code 5mwa). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Human Seh Phosphatase in Complex with 3-4-3,4-Dichlorophenyl-5-Phenyl- 1,3-Oxazol-2-Yl-Benzoic-Acid, PDB code: 5mwa: Magnesium binding site 1 out of 1 in 5mwaGo back to Magnesium Binding Sites List in 5mwa
Magnesium binding site 1 out
of 1 in the Human Seh Phosphatase in Complex with 3-4-3,4-Dichlorophenyl-5-Phenyl- 1,3-Oxazol-2-Yl-Benzoic-Acid
Mono view Stereo pair view
Reference:
J.S.Kramer,
S.Woltersdorf,
T.Duflot,
K.Hiesinger,
F.F.Lillich,
F.Knoll,
S.K.Wittmann,
F.M.Klingler,
S.Brunst,
A.Chaikuad,
C.Morisseau,
B.D.Hammock,
C.Buccellati,
A.Sala,
G.E.Rovati,
M.Leuillier,
S.Fraineau,
J.Rondeaux,
V.Hernandez Olmos,
J.Heering,
D.Merk,
D.Pogoryelov,
D.Steinhilber,
S.Knapp,
J.Bellien,
E.Proschak.
Discovery of First in Vivo Active Inhibitors of Soluble Epoxide Hydrolase (Seh) Phosphatase Domain. J.Med.Chem. 2019.
Page generated: Sun Sep 29 23:01:52 2024
ISSN: ISSN 0022-2623 PubMed: 31436984 DOI: 10.1021/ACS.JMEDCHEM.9B00445 |
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