Magnesium in PDB 5n96: Crystal Structure of Drosophila DHX36 Helicase in Complex with Agggtttttt

All present enzymatic activity of Crystal Structure of Drosophila DHX36 Helicase in Complex with Agggtttttt:
3.6.1.3;

The structure of Crystal Structure of Drosophila DHX36 Helicase in Complex with Agggtttttt, PDB code: 5n96 was solved by W.-F.Chen, S.Rety, H.-L.Guo, W.-Q.Wu, N.-N.Liu, Q.-W.Liu, Y.-X.Dai, X.-G.Xi, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	56.65 / 2.72
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	303.389, 51.316, 164.602, 90.00, 114.57, 90.00
R / Rfree (%)	18 / 24.8

The binding sites of Magnesium atom in the Crystal Structure of Drosophila DHX36 Helicase in Complex with Agggtttttt (pdb code 5n96). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Crystal Structure of Drosophila DHX36 Helicase in Complex with Agggtttttt, PDB code: 5n96:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Crystal Structure of Drosophila DHX36 Helicase in Complex with Agggtttttt


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of Drosophila DHX36 Helicase in Complex with Agggtttttt within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1001 b:44.6 occ:1.00 OD2 A:ASP266 2.8 41.1 1.0 CG A:ASP266 3.6 43.5 1.0 CB A:ASP266 3.8 34.9 1.0 CD2 A:LEU272 3.8 51.9 1.0 O A:ASP266 4.0 48.2 1.0 CB A:GLN262 4.0 38.1 1.0 CD1 A:LEU259 4.1 29.9 1.0 O A:GLN262 4.3 36.0 1.0 CA A:MET269 4.4 42.8 1.0 OE1 A:GLN262 4.5 49.5 1.0 C A:GLN262 4.5 35.0 1.0 CG A:MET269 4.7 46.6 1.0 OD1 A:ASP266 4.7 50.8 1.0 CB A:ASN271 4.8 35.1 1.0 CA A:ASP266 4.8 36.3 1.0 C A:ASP266 4.8 38.9 1.0 CB A:MET269 4.9 36.1 1.0 N A:LEU263 4.9 29.2 1.0 CA A:GLN262 5.0 31.1 1.0

Magnesium binding site 2 out of 2 in the Crystal Structure of Drosophila DHX36 Helicase in Complex with Agggtttttt


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Crystal Structure of Drosophila DHX36 Helicase in Complex with Agggtttttt within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg1001 b:76.6 occ:1.00 OD2 B:ASP266 2.7 51.5 1.0 CG B:ASP266 3.6 55.2 1.0 CD2 B:LEU272 3.8 49.2 1.0 CB B:ASP266 3.9 52.4 1.0 CB B:GLN262 4.0 33.2 1.0 CD1 B:LEU259 4.0 27.1 1.0 OE1 B:GLN262 4.1 53.9 1.0 O B:ASP266 4.3 47.5 1.0 O B:GLN262 4.4 37.2 1.0 CA B:MET269 4.6 44.0 1.0 C B:GLN262 4.6 35.7 1.0 O B:HOH1138 4.7 42.2 1.0 OD1 B:ASP266 4.8 49.2 1.0 CD B:GLN262 4.8 46.9 1.0 CB B:ASN271 4.9 38.4 1.0 CG B:MET269 4.9 46.5 1.0 CG B:GLN262 5.0 45.3 1.0 CD2 B:LEU263 5.0 41.0 1.0

W.F.Chen, S.Rety, H.L.Guo, Y.X.Dai, W.Q.Wu, N.N.Liu, D.Auguin, Q.W.Liu, X.M.Hou, S.X.Dou, X.G.Xi. Molecular Mechanistic Insights Into Drosophila DHX36-Mediated G-Quadruplex Unfolding: A Structure-Based Model. Structure V. 26 403 2018.
ISSN: ISSN 1878-4186
PubMed: 29429875
DOI: 10.1016/J.STR.2018.01.008