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Magnesium in PDB 5no1: Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Complex with Magnesium and the Insti XZ407 (Compound 5G)Enzymatic activity of Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Complex with Magnesium and the Insti XZ407 (Compound 5G)
All present enzymatic activity of Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Complex with Magnesium and the Insti XZ407 (Compound 5G):
2.7.7.49; 2.7.7.7; 3.1.26.4; Protein crystallography data
The structure of Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Complex with Magnesium and the Insti XZ407 (Compound 5G), PDB code: 5no1
was solved by
V.E.Pye,
P.Cherepanov,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5no1:
The structure of Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Complex with Magnesium and the Insti XZ407 (Compound 5G) also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Complex with Magnesium and the Insti XZ407 (Compound 5G)
(pdb code 5no1). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 3 binding sites of Magnesium where determined in the Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Complex with Magnesium and the Insti XZ407 (Compound 5G), PDB code: 5no1: Jump to Magnesium binding site number: 1; 2; 3; Magnesium binding site 1 out of 3 in 5no1Go back to Magnesium Binding Sites List in 5no1
Magnesium binding site 1 out
of 3 in the Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Complex with Magnesium and the Insti XZ407 (Compound 5G)
Mono view Stereo pair view
Magnesium binding site 2 out of 3 in 5no1Go back to Magnesium Binding Sites List in 5no1
Magnesium binding site 2 out
of 3 in the Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Complex with Magnesium and the Insti XZ407 (Compound 5G)
Mono view Stereo pair view
Magnesium binding site 3 out of 3 in 5no1Go back to Magnesium Binding Sites List in 5no1
Magnesium binding site 3 out
of 3 in the Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Complex with Magnesium and the Insti XZ407 (Compound 5G)
Mono view Stereo pair view
Reference:
X.Z.Zhao,
S.J.Smith,
D.P.Maskell,
M.Metifiot,
V.E.Pye,
K.Fesen,
C.Marchand,
Y.Pommier,
P.Cherepanov,
S.H.Hughes,
T.R.Burke.
Structure-Guided Optimization of Hiv Integrase Strand Transfer Inhibitors. J. Med. Chem. V. 60 7315 2017.
Page generated: Mon Dec 14 20:56:10 2020
ISSN: ISSN 1520-4804 PubMed: 28737946 DOI: 10.1021/ACS.JMEDCHEM.7B00596 |
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