Atomistry » Magnesium » PDB 5nol-5o5w » 5o26
Atomistry »
  Magnesium »
    PDB 5nol-5o5w »
      5o26 »

Magnesium in PDB 5o26: Crystal Structure of WNK3 Kinase Domain in A Diphosphorylated State and in Complex with Amp-Pnp/MG2+

Enzymatic activity of Crystal Structure of WNK3 Kinase Domain in A Diphosphorylated State and in Complex with Amp-Pnp/MG2+

All present enzymatic activity of Crystal Structure of WNK3 Kinase Domain in A Diphosphorylated State and in Complex with Amp-Pnp/MG2+:
2.7.11.1;

Protein crystallography data

The structure of Crystal Structure of WNK3 Kinase Domain in A Diphosphorylated State and in Complex with Amp-Pnp/MG2+, PDB code: 5o26 was solved by D.M.Pinkas, J.C.Bufton, J.A.Newman, J.Kopec, O.Borkowska, R.Chalk, N.A.Burgess-Brown, F.Von Delft, C.H.Arrowsmith, A.M.Edwards, C.Bountra, A.Bullock, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 47.66 / 2.38
Space group P 1
Cell size a, b, c (Å), α, β, γ (°) 36.163, 56.400, 71.236, 79.79, 80.73, 90.00
R / Rfree (%) 22.8 / 27.8

Magnesium Binding Sites:

The binding sites of Magnesium atom in the Crystal Structure of WNK3 Kinase Domain in A Diphosphorylated State and in Complex with Amp-Pnp/MG2+ (pdb code 5o26). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 4 binding sites of Magnesium where determined in the Crystal Structure of WNK3 Kinase Domain in A Diphosphorylated State and in Complex with Amp-Pnp/MG2+, PDB code: 5o26:
Jump to Magnesium binding site number: 1; 2; 3; 4;

Magnesium binding site 1 out of 4 in 5o26

Go back to Magnesium Binding Sites List in 5o26
Magnesium binding site 1 out of 4 in the Crystal Structure of WNK3 Kinase Domain in A Diphosphorylated State and in Complex with Amp-Pnp/MG2+


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of WNK3 Kinase Domain in A Diphosphorylated State and in Complex with Amp-Pnp/MG2+ within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mg502

b:11.7
occ:1.00
 OD1 A:ASN280 2.0 14.2 1.0
OD2 A:ASP294 2.1 12.5 1.0
O A:HOH615 2.1 13.1 1.0
O2G A:ANP501 2.2 19.3 1.0
O2A A:ANP501 2.2 18.2 1.0
O A:HOH645 2.4 12.2 1.0
CG A:ASP294 2.6 11.2 1.0
OD1 A:ASP294 3.0 10.4 1.0
CG A:ASN280 3.2 12.6 1.0
PG A:ANP501 3.5 16.4 1.0
PA A:ANP501 3.5 15.4 1.0
CB A:ASP294 3.7 10.8 1.0
O A:HOH621 3.8 17.4 1.0
O1A A:ANP501 3.9 19.6 1.0
ND2 A:ASN280 3.9 13.0 1.0
N3B A:ANP501 3.9 16.8 1.0
O A:ASP279 4.0 11.3 1.0
O3G A:ANP501 4.0 17.6 1.0
NZ A:LYS159 4.2 11.4 1.0
CB A:ASN280 4.4 11.8 1.0
O5' A:ANP501 4.4 18.4 1.0
CA A:ASN280 4.5 10.7 1.0
C8 A:ANP501 4.5 15.4 1.0
OD2 A:ASP279 4.5 15.7 1.0
C A:ASP279 4.5 13.3 1.0
O3A A:ANP501 4.6 18.6 1.0
O1G A:ANP501 4.7 16.5 1.0
N A:ASN280 4.7 11.4 1.0
N7 A:ANP501 4.8 18.0 1.0
CE A:LYS277 4.9 13.0 1.0
PB A:ANP501 4.9 21.4 1.0

Magnesium binding site 2 out of 4 in 5o26

Go back to Magnesium Binding Sites List in 5o26
Magnesium binding site 2 out of 4 in the Crystal Structure of WNK3 Kinase Domain in A Diphosphorylated State and in Complex with Amp-Pnp/MG2+


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Crystal Structure of WNK3 Kinase Domain in A Diphosphorylated State and in Complex with Amp-Pnp/MG2+ within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mg503

b:21.6
occ:1.00
 O1A A:ANP501 2.1 19.6 1.0
O3G A:ANP501 2.2 17.6 1.0
O2B A:ANP501 2.6 25.3 1.0
PA A:ANP501 3.5 15.4 1.0
PB A:ANP501 3.7 21.4 1.0
PG A:ANP501 3.7 16.4 1.0
O3A A:ANP501 3.8 18.6 1.0
O A:HOH613 4.0 20.3 1.0
NZ A:LYS277 4.1 14.9 1.0
O A:HOH615 4.2 13.1 1.0
O2A A:ANP501 4.3 18.2 1.0
N3B A:ANP501 4.3 16.8 1.0
OD2 A:ASP279 4.4 15.7 1.0
O2G A:ANP501 4.5 19.3 1.0
CA A:GLY156 4.5 22.9 1.0
O3' A:ANP501 4.6 22.3 1.0
O5' A:ANP501 4.6 18.4 1.0
O1G A:ANP501 4.7 16.5 1.0
C5' A:ANP501 4.7 19.7 1.0
CE A:LYS277 4.9 13.0 1.0
O1B A:ANP501 4.9 22.7 1.0

Magnesium binding site 3 out of 4 in 5o26

Go back to Magnesium Binding Sites List in 5o26
Magnesium binding site 3 out of 4 in the Crystal Structure of WNK3 Kinase Domain in A Diphosphorylated State and in Complex with Amp-Pnp/MG2+


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of Crystal Structure of WNK3 Kinase Domain in A Diphosphorylated State and in Complex with Amp-Pnp/MG2+ within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Mg502

b:15.8
occ:1.00
 OD1 B:ASN280 2.0 14.7 1.0
OD2 B:ASP294 2.0 15.5 1.0
O B:HOH629 2.2 21.5 1.0
O1G B:ANP501 2.3 12.1 1.0
O B:HOH602 2.4 13.4 1.0
O1A B:ANP501 3.0 15.0 1.0
CG B:ASP294 3.1 15.4 1.0
CG B:ASN280 3.1 16.2 1.0
O B:ASP279 3.5 16.4 1.0
PG B:ANP501 3.6 10.3 1.0
O2A B:ANP501 3.6 13.0 1.0
OD1 B:ASP294 3.8 12.4 1.0
PA B:ANP501 3.8 13.8 1.0
OD2 B:ASP279 3.9 22.1 1.0
O3G B:ANP501 3.9 13.9 1.0
ND2 B:ASN280 3.9 10.9 1.0
C B:ASP279 4.0 16.8 1.0
CA B:ASN280 4.1 15.2 1.0
CB B:ASP294 4.1 10.4 1.0
N B:ASN280 4.2 15.9 1.0
CB B:ASN280 4.2 12.1 1.0
CE B:LYS277 4.3 13.1 1.0
N3B B:ANP501 4.3 18.2 1.0
O B:HOH645 4.5 15.3 1.0
CG B:ASP279 4.5 20.6 1.0
CB B:ASP279 4.6 13.4 1.0
O3A B:ANP501 4.7 14.9 1.0
O2G B:ANP501 4.8 14.2 1.0
NZ B:LYS159 4.9 12.3 1.0
CA B:ASP279 5.0 12.9 1.0

Magnesium binding site 4 out of 4 in 5o26

Go back to Magnesium Binding Sites List in 5o26
Magnesium binding site 4 out of 4 in the Crystal Structure of WNK3 Kinase Domain in A Diphosphorylated State and in Complex with Amp-Pnp/MG2+


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 4 of Crystal Structure of WNK3 Kinase Domain in A Diphosphorylated State and in Complex with Amp-Pnp/MG2+ within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Mg503

b:17.5
occ:1.00
 O3G B:ANP501 2.1 13.9 1.0
O1B B:ANP501 2.1 11.9 1.0
O2A B:ANP501 2.2 13.0 1.0
O B:HOH602 3.3 13.4 1.0
PB B:ANP501 3.5 14.7 1.0
PA B:ANP501 3.5 13.8 1.0
NZ B:LYS277 3.6 10.1 1.0
PG B:ANP501 3.6 10.3 1.0
O3A B:ANP501 4.0 14.9 1.0
O B:HOH633 4.1 9.3 1.0
O5' B:ANP501 4.1 21.6 1.0
N3B B:ANP501 4.2 18.2 1.0
O2G B:ANP501 4.5 14.2 1.0
O1G B:ANP501 4.5 12.1 1.0
CA B:GLY156 4.5 20.6 1.0
CE B:LYS277 4.5 13.1 1.0
OD2 B:ASP279 4.5 22.1 1.0
O2B B:ANP501 4.6 18.7 1.0
N B:ALA157 4.7 18.4 1.0
O1A B:ANP501 4.7 15.0 1.0

Reference:

D.M.Pinkas, G.M.Daubner, J.C.Bufton, S.G.Bartual, C.E.Sanvitale, D.R.Alessi, A.Bullock. Crystal Structure of WNK3 Kinase Domain in A Diphosphorylated State and in Complex with Amp-Pnp/MG2+ To Be Published.
Page generated: Sun Sep 29 23:43:48 2024

Last articles

Zn in 9JPJ
Zn in 9JP7
Zn in 9JPK
Zn in 9JPL
Zn in 9GN6
Zn in 9GN7
Zn in 9GKU
Zn in 9GKW
Zn in 9GKX
Zn in 9GL0
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy