Magnesium in PDB 5o2l: Myosin VI Motor Domain in the Pre-Transition State

The structure of Myosin VI Motor Domain in the Pre-Transition State, PDB code: 5o2l was solved by T.Isabet, H.Benisty, A.Houdusse, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	22.18 / 2.20
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	72.340, 83.830, 177.660, 90.00, 90.00, 90.00
R / Rfree (%)	18.2 / 22.7

The structure of Myosin VI Motor Domain in the Pre-Transition State also contains other interesting chemical elements:

Fluorine

(F)

3 atoms

The binding sites of Magnesium atom in the Myosin VI Motor Domain in the Pre-Transition State (pdb code 5o2l). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Myosin VI Motor Domain in the Pre-Transition State, PDB code: 5o2l:

Magnesium binding site 1 out of 1 in the Myosin VI Motor Domain in the Pre-Transition State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Myosin VI Motor Domain in the Pre-Transition State within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg802 b:45.5 occ:1.00 F2 A:BEF803 1.7 52.6 1.0 OG1 A:THR158 2.0 44.3 1.0 O A:HOH902 2.1 39.9 1.0 OG A:SER204 2.1 50.9 1.0 O A:HOH937 2.2 38.1 1.0 O1B A:ADP801 2.2 42.5 1.0 CB A:THR158 3.1 45.0 1.0 CB A:SER204 3.1 44.6 1.0 BE A:BEF803 3.2 51.2 1.0 PB A:ADP801 3.4 45.5 1.0 O3B A:ADP801 3.4 39.8 1.0 N A:SER204 3.7 41.5 1.0 CG2 A:THR158 4.0 42.6 1.0 CA A:SER204 4.0 41.7 1.0 F1 A:BEF803 4.0 52.6 1.0 F3 A:BEF803 4.1 48.2 1.0 N A:THR158 4.1 41.0 1.0 O1A A:ADP801 4.1 43.9 1.0 CA A:THR158 4.1 40.8 1.0 OD1 A:ASP456 4.2 56.1 1.0 OD2 A:ASP456 4.3 63.5 1.0 O3A A:ADP801 4.3 45.8 1.0 O A:HOH921 4.4 47.4 1.0 O2B A:ADP801 4.5 44.2 1.0 O A:ASN202 4.6 43.1 1.0 PA A:ADP801 4.6 44.0 1.0 CG A:ASP456 4.7 57.4 1.0 ND2 A:ASN200 4.7 37.4 1.0 O2A A:ADP801 4.8 45.1 1.0 C A:SER203 4.8 43.7 1.0 O A:HOH1009 4.8 69.5 1.0 CE A:LYS157 4.9 39.8 1.0

F.Blanc, T.Isabet, H.Benisty, H.L.Sweeney, M.Cecchini, A.Houdusse. An Intermediate Along the Recovery Stroke of Myosin VI Revealed By X-Ray Crystallography and Molecular Dynamics. Proc. Natl. Acad. Sci. V. 115 6213 2018U.S.A..
ISSN: ESSN 1091-6490
PubMed: 29844196
DOI: 10.1073/PNAS.1711512115