Magnesium in PDB 5of9: Crystal Structure of Human MORC2 (Residues 1-603)

The structure of Crystal Structure of Human MORC2 (Residues 1-603), PDB code: 5of9 was solved by C.H.Douse, M.Shamin, Y.Modis, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	64.91 / 1.81
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	66.170, 127.930, 80.190, 90.00, 101.22, 90.00
R / Rfree (%)	16.1 / 18.8

The structure of Crystal Structure of Human MORC2 (Residues 1-603) also contains other interesting chemical elements:

Zinc

(Zn)

2 atoms

The binding sites of Magnesium atom in the Crystal Structure of Human MORC2 (Residues 1-603) (pdb code 5of9). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Crystal Structure of Human MORC2 (Residues 1-603), PDB code: 5of9:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Crystal Structure of Human MORC2 (Residues 1-603)


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of Human MORC2 (Residues 1-603) within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg703 b:20.8 occ:1.00 O2G A:ANP702 2.0 19.6 1.0 O A:HOH872 2.1 20.4 1.0 O1B A:ANP702 2.1 22.8 1.0 OD1 A:ASN39 2.1 19.1 1.0 O1A A:ANP702 2.1 19.7 1.0 O A:HOH902 2.1 20.5 1.0 HD21 A:ASN39 3.0 22.8 1.0 CG A:ASN39 3.1 17.7 1.0 PB A:ANP702 3.1 21.6 1.0 HZ2 A:LYS89 3.2 24.1 1.0 PA A:ANP702 3.3 21.6 1.0 PG A:ANP702 3.3 20.7 1.0 ND2 A:ASN39 3.4 19.0 1.0 O3A A:ANP702 3.4 19.5 1.0 N3B A:ANP702 3.6 21.5 1.0 HA3 A:GLY103 3.7 26.3 1.0 O A:HOH891 3.9 26.1 1.0 NZ A:LYS89 3.9 20.1 1.0 HA3 A:GLY98 3.9 24.0 1.0 HA2 A:GLY98 3.9 24.0 1.0 H A:GLY103 4.0 23.7 1.0 O5' A:ANP702 4.0 19.9 1.0 HZ1 A:LYS89 4.0 24.1 1.0 HZ3 A:LYS89 4.0 24.1 1.0 HNB1 A:ANP702 4.1 25.8 1.0 H A:LEU104 4.1 22.6 1.0 OE1 A:GLU35 4.1 24.6 1.0 O3G A:ANP702 4.2 21.0 1.0 HD22 A:ASN39 4.3 22.8 1.0 HA A:ASN39 4.3 23.3 1.0 O1G A:ANP702 4.3 22.9 1.0 O A:GLU35 4.3 21.9 1.0 CA A:GLY98 4.4 19.9 1.0 HB2 A:ASP38 4.4 22.1 1.0 CB A:ASN39 4.4 20.1 1.0 CA A:GLY103 4.5 21.9 1.0 O2B A:ANP702 4.5 20.6 1.0 N A:GLY103 4.5 19.7 1.0 H3' A:ANP702 4.5 25.8 1.0 O2A A:ANP702 4.6 20.1 1.0 N A:LEU104 4.6 18.8 1.0 HB3 A:GLU35 4.7 30.6 1.0 HZ2 A:LYS427 4.7 36.5 1.0 H A:ASN39 4.7 22.4 1.0 CA A:ASN39 4.7 19.4 1.0 N A:ASN39 4.8 18.7 1.0 C A:GLY103 4.9 19.7 1.0 HB3 A:ASP38 4.9 22.1 1.0 HD2 A:LYS89 4.9 64.8 1.0 HB3 A:ASN39 4.9 24.2 1.0 OD2 A:ASP42 5.0 28.7 1.0 HB2 A:ASN39 5.0 24.2 1.0

Magnesium binding site 2 out of 2 in the Crystal Structure of Human MORC2 (Residues 1-603)


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Crystal Structure of Human MORC2 (Residues 1-603) within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg703 b:22.2 occ:1.00 O B:HOH865 2.0 19.6 1.0 O1G B:ANP702 2.0 23.5 1.0 OD1 B:ASN39 2.1 23.4 1.0 O B:HOH907 2.1 23.2 1.0 O1A B:ANP702 2.1 20.4 1.0 O1B B:ANP702 2.1 21.0 1.0 HD21 B:ASN39 3.0 29.0 1.0 CG B:ASN39 3.0 23.1 1.0 PB B:ANP702 3.2 20.9 1.0 HZ2 B:LYS89 3.3 27.2 1.0 PA B:ANP702 3.3 23.8 1.0 PG B:ANP702 3.3 25.6 1.0 ND2 B:ASN39 3.4 24.1 1.0 O3A B:ANP702 3.4 22.0 1.0 N3B B:ANP702 3.6 19.9 1.0 HA3 B:GLY103 3.7 25.9 1.0 H B:GLY103 3.9 25.2 1.0 HA3 B:GLY98 3.9 34.0 1.0 O B:HOH910 3.9 23.7 1.0 NZ B:LYS89 4.0 22.6 1.0 O5' B:ANP702 4.0 23.8 1.0 HA2 B:GLY98 4.0 34.0 1.0 H B:LEU104 4.0 25.3 1.0 HZ1 B:LYS89 4.0 27.2 1.0 HZ3 B:LYS89 4.1 27.2 1.0 OE2 B:GLU35 4.1 27.5 1.0 HD22 B:ASN39 4.2 29.0 1.0 HA B:ASN39 4.3 29.8 1.0 O3G B:ANP702 4.3 21.9 1.0 O B:GLU35 4.3 21.3 1.0 O2G B:ANP702 4.4 23.4 1.0 CB B:ASN39 4.4 20.8 1.0 CA B:GLY98 4.4 28.3 1.0 CA B:GLY103 4.4 21.6 1.0 N B:GLY103 4.4 21.0 1.0 HNB1 B:ANP702 4.5 24.0 1.0 HB2 B:ASP38 4.5 26.3 1.0 N B:LEU104 4.5 21.1 1.0 O2B B:ANP702 4.5 24.4 1.0 H3' B:ANP702 4.6 30.0 1.0 O2A B:ANP702 4.6 21.4 1.0 H B:ASN39 4.7 29.3 1.0 HB3 B:GLU35 4.7 25.2 1.0 CA B:ASN39 4.7 24.8 1.0 N B:ASN39 4.8 24.4 1.0 HZ2 B:LYS427 4.8 48.5 1.0 C B:GLY103 4.9 19.5 1.0 HB3 B:ASP38 4.9 26.3 1.0 HB3 B:ASN39 4.9 25.0 1.0 HB2 B:ASN39 4.9 25.0 1.0 OD2 B:ASP42 4.9 29.8 1.0 HB2 B:LEU104 5.0 24.2 1.0

C.H.Douse, S.Bloor, Y.Liu, M.Shamin, I.A.Tchasovnikarova, R.T.Timms, P.J.Lehner, Y.Modis. Neuropathic MORC2 Mutations Perturb Ghkl Atpase Dimerization Dynamics and Epigenetic Silencing By Multiple Structural Mechanisms. Nat Commun V. 9 651 2018.
ISSN: ESSN 2041-1723
PubMed: 29440755
DOI: 10.1038/S41467-018-03045-X